[Pseudohiponatremia secondary to hypertriglyceridemia during the treatment of lymphoblastic lymphoma with corticoids and L-asparaginase].

Unlabelled: L-asparaginase (L-asp) is an antineoplastic drug used in Leukemia and Lymphoma treatment protocols. Alterations in lipid metabolism have been reported in 10-50% of children treated with L-Asp.

Objective: To report an unusual complication of lipid metabolism associated with the use of L-Asp.

[Benefits of home-based administration of palivizumab in high-risk groups].

Unlabelled: Palivizumab, a humanized monoclonal antibody against the respiratory syncytial virus (RSV), currently is indicated in groups at higher risk of developing severe RSV disease, such as extreme premature infants and patients with hemodynamically significant heart disease. In Chile, this strategy is guaranteed by Law 20850 (Ricarte Soto Law). Nevertheless, barriers to its administration included the need to transfer these labile patients and exposure to other users, with the risk of contagion in waiting rooms.

[Validation and cross-cultural adaptation of the Pediatric Sleep Questionnaire Sleep-Related Breathing Disorder Scale (PSQ-SRBD) to spanish language].

Unlabelled: In the Chilean pediatric population, to date, there is no validated screening instrument for sleep-related breathing disorders (SRBD).

Objective: to develop and validate a cross-cultural adaptation of the Pediatric Sleep Questionnaire - sleep-related breathing disorder scale (PSQ-SRBD), by creating the Chilean Spanish version (PSQ-CL).

Patients And Method: The PSQ-SRBD was translated from English into Chilean Spanish, obtaining the PSQ-CL, which was subsequently validated.

[Exploring the sexual and reproductive health of migrant adolescents in Chile: insights from the 10th National Youth Survey].

Unlabelled: Migration is a phenomenon with an impact on the health of adolescents. Barriers to accessing health services expose them to risks such as sexual violence, unwanted pregnancies, and sexually transmitted infections/HIV.

Objective: To analyze variables of sexual and reproductive health in migrant and Chilean adolescents.

[Health Related Quality of Life in retinoblastoma patients].

Unlabelled: Retinoblastoma (Rb) is the most common intraocular cancer in children and, along with its treatment, can negatively impact the Quality of Life (QoL). Few studies have explored this subject in these patients; none in Latin America.

Objective: To evaluate the general, physical, emotional, social, and school quality of life of patients treated for Rb and to analyze which patient, disease, or treatment factors are associated with worse outcomes.

[Estimation of cardiorespiratory fitness from the Six-Minute Walk Test in schoolchildren].

Unlabelled: Cardiorespiratory fitness can be assessed by direct, indirect, maximal, and moderate effort, running, cycling, or walking methods.

Objective: To predict maximum oxygen consumption (V O2max) from the six-minute walk test in schoolchildren.

Patients And Method: 459 students were included, 215 were male and 244 were female, aged 11.

[Properties of the Test of Early Learning and Development, second edition "TADI", in the context of scale validation policies for children under 6 years of age in Chile and Latin America].

Unlabelled: In Latin America, scales have been built to assess Early Child Development (EChD), most of them for direct evaluations. In Chile, the Psychomotor Development Evaluation Scale (EEDP) and the Test of Psychomotor Development (TEPSI) were developed in the 70's and 80's and are still used in different Spanish-speaking countries, but have not been updated or revalidated. In response to the need for a new instrument built in Chile for the evaluation of EChD on a large scale, the Test of Early Learning and Development (TADI-2, for its acronym in Spanish) was built and standardized between 2009 and 2012.

[Paroxysmal Nocturnal Hemoglobinuria: A Rare but Treatable Cause of Acute Kidney Injury. Case Report].

Early recognition of acute kidney injury is essential to prevent progression to chronic kidney disease. We present the case of a 19-year-old man with multiple emergency department visits for fatigue, abdominal pain, and intermittent dark urine. Upon admission, he had pancytopenia with elements suggestive of hemolysis and acute kidney injury.

[Case Report: Guillain-Barré Syndrome with Difficult-to-manage Pain and Persistent Urinary Retention].

Guillain-Barré Syndrome (GBS) is an acute inflammatory polyradiculoneuropathy that affects the peripheral nervous system, predominantly impairing motor function. Pain, both somatic and neuropathic, is reported in 89% of cases and is refractory to first-line analgesics in most of these. We present the case of a 75-year-old woman with an acute presentation of areflexic flaccid tetraparesis compatible with GBS.

[Consensus Recommendations for Lung Cancer Screening in Chile].

Unlabelled: Lung cancer is the leading cause of cancer death worldwide, also in Chile, where the main risk factor is smoking. Early detection using low-dose computed tomography has been shown to reduce mortality from this cause, but there are still no formal screening recommendations in Chile.

Aim: This initiative aimed to develop recommendations for lung cancer screening in Chile through an expert consensus process.

[Workplace Inclusion for Individuals with Psychiatric Disabilities under Law 21.015: A Narrative Review to Understand Its Implications for Healthcare Teams].

Unlabelled: Individuals with psychiatric disabilities face significant challenges in achieving workforce inclusion, presenting a critical public health issue. The enactment of Law 21.015 on this matter offers an opportunity for improvement.

[Tacrolimus in Difficult to Treat Proteinuria Associated with Lupus Nephritis. Experience of 3 Centers].

Unlabelled: The management of proteinuria in patients with lupus nephritis represents a challenge for the specialist. Recently, Calcineurin Inhibitors have been positioned as an effective alternative in these patients, but their use is not widespread in our country. We report the experience of three centers in this regard.

[Association of the 5HTTLPR/rs25531 Genetic Variant with Depression in a Cohort of Primary Care Patients].

Unlabelled: Serotonin plays a central role in mood regulation and the development of depressive disorders. The serotonin transporter, the primary regulator of serotonin levels, presents genetic variants that affect its functionality.

Aim: To study whether functional bi-allelic 5-HTTLPR or tri-allelic 5-HTTLPR/rs25531 polymorphisms in the serotonin transporter gene are associated with the diagnosis of depression.

[Characteristics of Hospitalized Adults with Severe Hyponatremia: A Comparison of Patients with Severe and Very Severe Hyponatremia in Terms of Etiology, Symptoms, Treatment Response, and Mortality].

Unlabelled: Hyponatremia is the most common hydroelectrolyte disorder in hospitalized patients. It is unclear whether there are differences between severe hyponatremia (<125 mEq/L) and very severe hyponatremia (<115 mEq/L) in terms of etiology, response to therapy, and mortality.

Aim: Describe the etiology, symptoms, response to treatment and mortality of hospitalized adults with severe and very severe hyponatremia.