Prolonged Transcriptional Consequences in Survivors of Sepsis.

Survivors of sepsis often suffer from prolonged post-critical illness syndrome secondary to the immune system's reprogramming. It is unclear if this process is static and pervasive due to methodological difficulties studying long-term outcomes of sepsis. The purpose of this study is to evaluate transcriptional profiles longitudinally in in the aftermath of sepsis to provide preliminary data for targets playing a role in post-sepsis immunostasis.