Idiopathic scoliosis, growth zones, magnetic therapy.

Background: The study has been performed to investigate the influence of pulsed magnetic field on the bone growth plates to get new grounds of magneto therapy in AIS treatment.

Materials And Methods: Were used methods of "strong" and "weak" pulsed magnetic fields influence.

Results: Application of pulsed magnetic field causes an authentic inhibition of chondrocytes' active proliferation processes, decreases the index of labeled nuclei, indicating the suppression of DNA synthesis, takes place an increase in the unit weight of the more "mature" differentiated chondrocytes.

Corrective exercises in multimodality therapy of idiopathic scoliosis in children - analysis of six weeks efficiency - pilot study.

The program of the special corrective exercises according to Schroth method in H.R. Weiss modification was carried out in multimodality conservative therapy of idiopathic scoliosis in our clinic.

Photodynamic impact on the epiphyseal plates.

This study was carried out to prove the possibility of inhibition of long bones epiphyseal plates activity with photodynamic impact. Comparative analysis of the Chlorin E6 accumulation with transcutaneous and intraperitoneal administration mode, carried out on 175 laboratory mice showed the drug accumulates selectively in the epiphyseal plates of long bones, regardless of the mode of administration. 15 mice (males and females) at the age of active grownig were subjected to the single laser radiation impact on the knee joints area: 5 ones with transcutaneous Chlorine E6 administration, another 5 ones with intraperitoneal administration and the rest 5 without the drug.

Neurohumoral regulation in children with idiopathic scoliosis.

Biotesting of blood serum in children aged 8-15 with adolescent idiopathic scoliosis (0°-60° by Cobb) showed the change of neurohumoral regulation in comparison with the age norm. The degree and direction of changes in the biotesting give the indication of the progression of spinal deformity. The effectiveness of treatment can be judged by control biotesting.

Typical and atypical AIS. Pathogenesis.

AIS hypothesis has the right to recognition, if it explains the transition of "healthy" vertebra column into status of "scoliotic" one. AIS is the most investigated disease in the history of orthopedics, but up the present time there is no clear explanation of some its phenomena: vertebra column mono-form deformation along with its poly etiology character, interrelation of its origin and development and child's growth process etc. The key for authors' view at AIS was scoliosis with non-standard (concave side) rotation.

Peculiarities of brain functioning in children with adolescence idiopathic scoliosis (AIS) according to EEG studies.

Brain structures with bioelectric activity (BA) different from BA of the same structures in healthy peers were revealed using an original 3DLocEEG analysis of EEGs that solves so-called "reverse EEG task". These were the following structures: thalamus, pineal gland, hypothalamic area, including suprahiasmatic nuclei, and infratemporal cortex. The shift of BA focus to structures of the left hemisphere including left thalamus was recorded in patients with AIS; the shift increased both with worsening of deformation and increasing progression activity.

Integrated assessment of back muscles bioelectrical activity and H-reflex research in AIS.

The study of the back muscles bioelectric activity in 216 children in the age between 10-15 years showed that the total paravertebral muscles bioelectrical activity on the convex side of the proximal curve and on the concave side of its distal part is higher compared with that on the opposite side. Analysis of H-reflex and M-responses in 302 patients in the age between 10-15 years created a normative database. This allows, in comparison with the total individual electrophysiological parameters, to determine patient's progression risk.