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IGF2BP2 attenuates intestinal epithelial cell ferroptosis in colitis by stabilizing mA-modified GPX4 mRNA.

Cytokine

January 2024

Department of Pediatric Gastroenterology, Children's Hospital of The First People's Hospital of Chenzhou City, Chenzhou 423000, Hunan Province, PR China. Electronic address:

Background: Ulcerative colitis (UC) is a chronic and uncontrolled inflammatory bowel disease. N-methyladenine (mA) is a reversible mRNA modification method. IGF2BP2 is an RNA-binding protein regulated by mA methylation.

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