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Systematic Review: Issues in Measuring Clinically Meaningful Change in Self-Reported Chronic Pediatric Pain Intensity.

J Pediatr Psychol

August 2016

Department of Child and Adolescent Psychiatry, Ann & Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, and Mary Ann and J. Milburn Smith Child Health Research Program, Children's Hospital of Chicago Research Center

Objective: This report examined limitations in our ability to assess clinically significant change (CSC) in randomized controlled trials of treatments of self-reported pediatric chronic pain intensity.

Methods: The following were reviewed: (a) approaches to assessing CSC; (b) approaches to assessing CSC used in psychological treatment studies of self-reported pediatric chronic pain intensity included in a recent systematic review; (c) the role of test-retest reliability in distribution-based CSC measures; (d) the test-retest reliability of recommended chronic pain measures.

Results And Conclusions: Existing studies do not assess whether a CSC occurred or use procedures that did not account for measurement error and true score fluctuations unrelated to treatment, possibly resulting in overestimating CSCs.

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