1 results match your criteria: "Children's Hospital SAMIC Prof. Dr. Juan P. Garrahan[Affiliation]"
Neonates Effects and Tolerability of Treprostinil in Hypertension with Persistent Pulmonary.
Am J Perinatol
July 2020
Neonatal Intensive Care Unit, Children's Hospital SAMIC Prof. Dr. Juan P. Garrahan, Buenos Aires, Argentina.
Article Synopsis
- The study investigated the effects of treprostinil on neonates with congenital diaphragmatic hernia and persistent pulmonary hypertension after one week of treatment, focusing on changes in the oxygenation index and other clinical outcomes.
- In a quasi-experimental design, 17 neonates were treated and monitored; results showed significant improvement in oxygenation, with 15 out of 17 patients surviving post-treatment, although some still had severe pulmonary hypertension.
- While treprostinil was generally well tolerated, some patients experienced adverse effects, and it suggested the need for further research to identify which patients might benefit the most from the treatment.