77 results match your criteria: "Children's Hospital Augsburg[Affiliation]"

Article Synopsis
  • Rhabdoid tumors primarily affect infants and very young children, who are at high risk for severe treatment side effects from invasive therapies like surgery, high dose chemotherapy, and radiotherapy.
  • Radiotherapy is a promising treatment for these tumors, especially in infants, as recent data indicate it can significantly improve mean survival time and overall survival rates, despite concerns about long-term side effects.
  • The study suggests that a more hopeful approach to treatment is warranted for young infants, as the potential benefits of radiotherapy may outweigh the risks.
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High-dose chemotherapy (HDCT) with auto-SCT in children with atypical teratoid/rhabdoid tumors (AT/RT): a report from the European Rhabdoid Registry (EU-RHAB).

Bone Marrow Transplant

March 2014

1] Swabian Children's Cancer Center, Children's Hospital Augsburg, Augsburg, Germany [2] Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.

A retrospective analysis of data from the European Rhabdoid Registry (EU-RHAB) was performed to describe the outcome of children with atypical teratoid/rhabdoid tumors (AT/RT) who underwent high-dose chemotherapy (HDCT) with auto-SCT. Nineteen patients (male, n=15; median age at diagnosis 21 months) were identified. Nine patients presented with metastatic disease at diagnosis.

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