1 results match your criteria: "Children's Hospital Affiliate to Xi'an Jiaotong University[Affiliation]"
Long noncoding RNA SNHG4 remits lipopolysaccharide-engendered inflammatory lung damage by inhibiting METTL3 - Mediated mA level of STAT2 mRNA.
Mol Immunol
November 2021
Neonatal Department, Children's Hospital Affiliate to Xi'an Jiaotong University, Xi'an, Shaanxi Province, 710003, China. Electronic address:
Background: Emerging evidence suggests that long non coding RNA (lncRNA) small nucleolar RNA host gene 4 (SNHG4) has become a new insight into lipopolysaccharide (LPS)-induced microglia inflammation, its role in neonatal pneumonia (NP) remains to be largely unrevealed.
Methods: RT-qPCR was used to determine the expression of SNHG4 and METTL3 in the serum from NP patients and normal volunteers, as well as in LPS treated-WI-38 cells. The SNHG4 overexpression vector (pcDNA-SNHG4) was transfected into LPS-treated cells.