924 results match your criteria: "Children's Heart Center[Affiliation]"
Fetal Diagn Ther
October 2024
Children's Heart Center Linz, Department of Pediatric Cardiology, Kepler University Hospital, Linz, Austria.
Introduction: Fetuses with hypoplastic left heart syndrome (HLHS) and intact atrial septum (IAS) have an overall poor prognosis and a high risk of neonatal death due to severe secondary lung damage. Intrauterine stenting of the atrial septum was introduced in these patients to enable survival.
Case Presentation: We present a case of a HLHS fetus with IAS and signs of incipient nutmeg lung, in whom at 30 weeks gestation an atrial stent was successfully placed but continuously developed subtotal stent-obstruction over the next weeks.
Radiol Case Rep
December 2024
The Children's Heart Center, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, 100 Hongkong Road, Jiangan District, Wuhan, Hubei, China.
JACC Adv
September 2024
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Int J Biol Macromol
November 2024
Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, 325027 Wenzhou, Zhejiang, China; Children's Heart Center, Institute of Cardiovascular Development and Translational Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China. Electronic address:
Cardiol Young
October 2024
Department of Pediatric Cardiology, Children's Heart Center, Nagoya University Hospital, Nagoya, Japan.
Hereditary connective tissue diseases have different risks of aortic dissection depending on the causative gene. We report a family with no extravascular phenotype and a clinical diagnosis of familial thoracic aortic aneurysm and dissection, but genetic testing confirmed p.Tyr470Cys in , which is typically the responsible gene for Loeys-Dietz syndrome.
View Article and Find Full Text PDFJ Pediatr Clin Pract
December 2024
Division of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
Objectives: Pulse oximetry screening of newborns detects critical congenital heart disease (CCHD). Rural birth location is known to affect timing and management of when infants with CHD undergo surgery, but its association with CCHD screening is unknown. We assess the relationship between rural location and postnatal CCHD diagnosis and describe lesion-specific modes of diagnosis.
View Article and Find Full Text PDFCancer Res
December 2024
Dana-Farber Cancer Institute, Boston, Massachusetts.
MYC deregulation occurs in the majority of multiple myeloma cases and is associated with progression and worse prognosis. Enhanced MYC expression occurs in about 70% of patients with multiple myeloma, but it is known to be driven by translocation or amplification events in only ∼40% of myelomas. Here, we used CRISPR interference to uncover an epigenetic mechanism of MYC regulation whereby increased accessibility of a plasma cell-type-specific enhancer leads to increased MYC expression.
View Article and Find Full Text PDFPediatr Cardiol
September 2024
Pediatric Neurodevelopmental Center, Atlanta, GA, USA.
To evaluate the association between initial management strategy of neonatal symptomatic Tetralogy of Fallot (sTOF) and later health-related quality of life (HRQOL) outcomes. We performed a multicenter, cross-sectional evaluation of a previously assembled cohort of infants with sTOF who underwent initial intervention at ≤ 30 days of age, between 2005 and 2017. Eligible patients' parents/guardians completed an age-appropriate Pediatric Quality of Life Inventory, a Pediatric Quality of Life Inventory Cardiac Module Heart Disease Symptoms Scale, and a parental survey.
View Article and Find Full Text PDFPediatr Cardiol
September 2024
Department of Pediatrics and Adolescent Medicine, Children's Heart Center, American University of Beirut Medical Center, Riad-El Solh1107 2020, PO Box 11-0236, Beirut, Lebanon.
Double-outlet right atrium is an extremely rare congenital cardiac defect, in which the right atrium drains into both ventricles. Here in, we present a peculiar case involving an 8-year-old female with double-outlet right atrium characterized by three distinct atrioventricular valves and a membranous ventricular septal defect. This is associated with right atrium to left ventricular flow through the accessory atrioventricular valve while maintaining adequate size of the right ventricle.
View Article and Find Full Text PDFJ Affect Disord
January 2025
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China. Electronic address:
Background: Previous observational studies have suggested that there appears to be a close association between mitochondrial function and psychiatric disorders, but whether a causal role exists remains unclear.
Methods: We extracted genetic instruments for 67 mitochondrial-related proteins and 10 psychiatric disorders from publicly available genome-wide association studies, and employed five distinct MR methods and false discovery rate correction to detect causal associations between them. Additionally, we conducted a series of sensitivity tests and additional model analysis to ensure the robustness of the results.
Front Public Health
September 2024
Department of Child Healthcare, Wenzhou People's Hospital, Wenzhou, China.
Background: The association between exposure to cadmium (Cd) and cardiovascular health (CVH) has received considerable scientific interest. However, findings thus far have been inconclusive, particularly regarding sex-specific effects and dose-response relationships. The aim of our study was to investigate the relationships of blood Cd levels with the overall and component CVH scores.
View Article and Find Full Text PDFEur Respir J
October 2024
Developmental Lung Biology and Cardiovascular Pulmonary Research Laboratories, University of Colorado, Denver, CO, USA.
Ecotoxicol Environ Saf
October 2024
Department of Nephrology, Henan Provincial Key Laboratory of Kidney Disease and Immunology, Henan Provincial Clinical Research Center for Kidney Disease, People's Hospital of Zhengzhou University and Henan Provincial People's Hospital, 7 Weiwu Road, Jinshui District, Zhengzhou, Henan 450053, China. Electronic address:
World J Pediatr Congenit Heart Surg
November 2024
Division of Pediatric Cardiology and Division of Cardiac Critical Care, Department of Pediatrics, Children's National Hospital, Washington, DC, USA.
The challenges of present-day healthcare are urgent; there is a shortage of clinicians, patient care is increasingly complex, resources are limited, clinician turnover seems ever-increasing, and the expectations of providers and patients are monumental. To transform problems into innovative opportunities, diverse perspectives and a sense of possibility are needed. The following is a collaborative manuscript authored by the speakers of the 8th World Congress of Pediatric Cardiology and Cardiac Surgery session, "Teamwork, Culture Change, and Strategy.
View Article and Find Full Text PDFJTCVS Tech
August 2024
Department of Pediatric Cardiovascular Surgery, Children's Heart Center, West China Second University Hospital, Sichuan University, Chengdu, China.
BMJ Open
August 2024
Institute of Health and Care Sciences, University of Gothenburg, Goteborg, Sweden.
Background: Young people with congenital heart disease (CHD) are frequently affected by discontinued follow-up when transferring from paediatric to adult care. Identified predictors for discontinuation include mostly patient-related factors, and further knowledge of hospital and healthcare system factors is needed.
Aim: This study aims to explore patient-related, hospital-related and healthcare system-related factors affecting continued follow-up care after transfer, as perceived and experienced by paediatric cardiology and adult CHD (ACHD) healthcare providers (HCPs) in Sweden and Belgium.
Cell Genom
September 2024
Institute for Molecular Medicine Finland, FIMM, Helsinki Institute of Life Science - HiLIFE, University of Helsinki, Helsinki, Finland; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
Kardiol Pol
August 2024
Children's Heart Center, American University of Beirut, Beirut, Lebanon.
J Arrhythm
August 2024
Division of Pediatric Cardiology, Department of Pediatrics West Virginia University School of Medicine and West Virginia University Children's Heart Center Morgantown West Virginia USA.
Masking of preexcitation from a slow-conducting, decremental AP due to preexcitation via an FV pathway.
View Article and Find Full Text PDFCirc Genom Precis Med
August 2024
Center for Cardiovascular Innovation (B.D., A.K., Z.L.), The University of British Columbia, Vancouver, Canada.
Arch Med Sci
June 2024
Department of Child Healthcare, Wenzhou People's Hospital, Wenzhou, Zhejiang Province, China.
Introduction: In this study, we investigated the effect of depression on the interaction between lung disease and cardiovascular health (CVH).
Methods: Utilising data from the National Health and Nutrition Examination Survey (2013-2018), we employed multivariate regression and bootstrap mediation analysis to explore the relationships among lung diseases, depression, and CVH scores.
Results: Complex and significant associations were identified among lung diseases, depression, and CVH scores, with depression mediating 9.
Int J Cardiol
October 2024
Pediatric Research Institute, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325027, Wenzhou, Zhejiang, China; Key Laboratory of Structural Malformations in Childern of Zhejiang Province, 325027, Wenzhou, Zhejiang, China; Children's Heart Center, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 325027 Wenzhou, China. Electronic address:
Background: Kawasaki disease (KD) is a kind of pediatric vasculitis, whose pathogenesis has not been elucidated until now. Many scholars believe that KD is one type of infectious diseases in the susceptible groups. However, no recognized pathogens are confirmed.
View Article and Find Full Text PDFFront Cardiovasc Med
July 2024
Department of Children's Heart Center, Fuwai Central China Cardiovascular Hospital, Fuwai Central China Hospital of Zhengzhou University, Henan Provincial People's Hospital Heart Center, Zhengzhou, Henan, China.
Objects: The aim of this study was to investigate the morphologic changes of a novel fully biodegradable implantable device after closing a perimembranous ventricular septal defect (Pm-VSD) and to evaluate the effect of the occluder on the myocardial function in patients during a 3-year follow-up period.
Methods: One-year, 2-year, and 3-year follow-ups were carried out after implantation with a total of 30 Pm-VSD patients who had successful closure by the fully biodegradable occluder. In total, 30 healthy children were enrolled as controls.
Pediatr Cardiol
July 2024
Pediatrics and Human Development, Michigan State University College of Human Medicine, East Lansing and Grand Rapids, MI, USA.
Bicuspid aortic valve (BAV) is the most common congenital heart defect. It can be accompanied by aortic regurgitation or stenosis with aortopathies. Studies in adults showed a sex difference, but there are limited number of reports in the pediatric population.
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