1,467 results match your criteria: "Chicago College of Medicine[Affiliation]"

Article Synopsis
  • This study investigates post-renal transplant (RT) medical management for heart failure with reduced ejection fraction (HFrEF) in patients with end-stage renal disease, highlighting a gap in research on this topic.* -
  • Out of 750 RT recipients studied, only 6.3% had a prior diagnosis of HFrEF, yet a significant portion improved in heart function before the transplant and received essential medications like beta blockers and RAAS inhibitors.* -
  • Results show low rates of cardiology follow-up and RAAS inhibitor usage post-transplant, indicating the need for better collaboration between cardiology and transplant teams to enhance care for these patients.*
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Adherence to Guidelines and Federal Psychotropic Medication Labels for the Treatment of Medicaid-Insured Children With ADHD.

Psychiatr Serv

November 2024

H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta (Kim, Keskinocak, Serban); Department of Psychiatry, University of Florida College of Medicine-Jacksonville, Jacksonville (Cuffe); Department of Psychiatry, University of Illinois Chicago College of Medicine, Chicago (Naylor).

Objective: This study examined adherence to clinical practice guidelines (CPGs) and U.S. Food and Drug Administration (FDA) medication labels when prescribing psychotropic medications to Medicaid-insured children with attention-deficit hyperactivity disorder (ADHD).

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Predictors of time to achieve clinically significant improvements following lateral lumbar interbody fusion.

J Clin Neurosci

December 2024

Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL 60612, United States. Electronic address:

Background: As lateral lumbar interbody fusions (LLIF) are increasingly performed, our understanding of postoperative clinical trajectories is important in informing preoperative patient expectations. While minimum clinically important difference (MCID) rates are widely utilized in spine surgery literature, there is less published on how long it takes for patients to achieve MCID following LLIF.

Objective: To evaluate the length of time it takes for patients to report MCID achievement for back pain, leg pain, disability, and physical function and evaluate predictors of time to achieve MCID.

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The transcription factor NRF2 plays an important role in many biological processes and is a promising therapeutic target for many disease states. NRF2 is highly expressed in the skin and is known to play a critical role in diabetic wound healing, a serious disease process for which treatment options are limited. However, many existing NRF2 activators display off-target effects due to their electrophilic mechanism, underscoring the need for alternative approaches.

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Introduction: With the growing population of pancreas transplant recipients followed long-term, some female recipients are going to require surgical intervention for gynecologic symptoms and pathologies. Currently, there is a lack of literature describing how to approach this population and whether pelvic gynecologic procedures (GYN) can be performed safely given the proximity of the pancreatic (and possibly renal) allograft. In this single-center retrospective analysis, all pancreas transplant recipients that subsequently underwent GYN were reviewed.

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Background: Perioperative adrenergic vasopressors in kidney transplantation have been linked to negative outcomes and arrhythmias. Synthetic angiotensin II (AT2S) could improve renal hemodynamics, preserve allograft function, and reduce arrhythmias.

Objective: We aimed to compare the effectiveness and safety of AT2S to adrenergic vasopressors when used for perioperative hypotension in kidney transplant.

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Few biological or clinical predictors guide medication selection and/or dosing for attention-deficit/hyperactivity disorder (ADHD). Accumulating data suggest that genetic factors may contribute to clinically relevant pharmacodynamic (e.g.

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Article Synopsis
  • The study aimed to evaluate how patient safety culture affects the overuse of cesarean deliveries in maternity care hospitals in Michigan.
  • Data was collected through an electronic survey completed by 3,091 clinicians across 54 hospitals, allowing for the analysis of factors influencing cesarean rates.
  • Findings suggest that while the culture promoting vaginal births is the strongest predictor for reducing cesarean deliveries, aspects of safety culture—like teamwork and communication—also play a significant role in lowering these rates.
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Background: Peritoneal metastases due to gastric adenocarcinoma (GCPM) carry a dismal prognosis. A promising treatment strategy is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), but clear eligibility criteria for GCPM are lacking. We sought to identify factors associated with overall survival (OS) following CRS-HIPEC for GCPM to help optimize patient selection and clinical outcomes.

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Objectives: Pediatric epistaxis is a common, often non-operative condition encountered by Otolaryngologists. The present study seeks to (1) describe our outcomes of epistaxis management, (2) estimate the associated healthcare burden, and (3) propose a clinical model to optimize care coordination with primary care and advanced practice providers.

Methods: Retrospective case series of pediatric patients treated outpatient for epistaxis by a single otolaryngologist from 2021 to 2022.

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We investigated the associations between sociodemographic factors, religiosity traits, and the perception of discrimination among Muslim Americans in both everyday life and medical settings. A self-administered web-based questionnaire, comprising validated measures of discrimination and religiosity, was completed by a convenience sample of English-speaking adult Muslim Americans, recruited through both in-person and online channels. Among the 1281 respondents, less than half were born in the USA (46%), and a significant portion displayed visible religious markers, such as wearing a hijab or having a beard (61%).

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To estimate differences in breastfeeding initiation and duration across dimensions of migration history (migration to the U.S. 50 states/District of Columbia [DC] in childhood, adulthood, or not at all) in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

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Returning individual research results to participants: Values, preferences, and expectations.

J Clin Transl Sci

September 2024

Breathe Chicago Center, Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois Chicago, Chicago, IL, USA.

Background/objective: Disclosing individual research results to participants is not standard practice. The return of individual research results to participants may increase recruitment, retention, and engagement in research. This study's objective was to explore the preferences, expectations, and experiences of research participants receiving individual research results.

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Introduction: Technology and internet access have become increasingly integrated into healthcare as the primary platform for health-related information and provider-patient communication. Disparities in access to digital resources exist in the United States and have been shown to impact health outcomes in various head and neck malignancies. Our objective is to evaluate the associations of digital inequity on health outcomes in patients with salivary gland cancer (SGC).

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Background: Healthcare provided without attending to patients' religious/spiritual needs contributes to inequities.

Objective: Assess Muslim American views on the importance and accessibility of religious/spiritual resources in hospitals.

Design/participants/main Measures: A survey was distributed at community events and online to self-reported Muslim adults.

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Purpose: Currently, 40% of counties in the United States do not have an obstetrician or midwife, and in rural areas the likelihood of childbirth being attended to by a family medicine (FM) physician is increasing. We sought to characterize the effect of the FM presence on unit culture and a key perinatal quality metric in Iowa hospital intrapartum units.

Methods: Using a cross-sectional design, we surveyed Iowa physicians, nurses, and midwives delivering intrapartum care at hospitals participating in a quality improvement initiative to decrease the incidence of cesarean delivery.

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The SARS-CoV-2 coronavirus (COVID-19) pandemic has had widespread implications on various aspects of life; however, there is a paucity of longitudinal data regarding its impact on sexual behavior. To assess the impact of the COVID-19 pandemic on changes in frequency of sexual activity and partner dynamics in the United States, we utilized data from the General Social Survey (GSS). This biannual survey of adults in the United States, provided responses from 12,791 participants, enabling a comparative analysis of sexual behaviors between pre-COVID-19 (2016 and 2018, n = 5215 respondents) and COVID-19 periods (2021 and 2022, n = 7576 respondents).

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Cowden syndrome (CS) is an autosomal dominant genetic disorder characterized by multiple hamartomas across various tissues and an elevated risk of several types of cancer, including breast, thyroid, and endometrial cancers. Skin findings can precede more serious malignancies, making early detection and diagnosis crucial. In this report, we detail four individual patient histories, including their initial dermatological symptoms or concerns.

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Introduction: For authors, selecting a target journal to submit a manuscript is a critical decision with career implications. In the discipline of medical education, research conducted in 2016 found that authors were influenced by multiple factors such as a journal's prestige and its mission. However, since this research was conducted the publishing landscape has shifted to include a broader variety of journals, an increased threat of predatory journals, and new publishing models.

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Purpose: The current study examined associations of social and built features of neighborhood environments with psychological distress 6 years later and whether these associations were explained by stress and social factors, among Hispanic/Latino adults from the HCHS/SOL and SOL CASAS Ancillary Study.

Methods: In the SOL CASAS Ancillary Study, HCHS/SOL San Diego participants' baseline (2008-2011) home addresses were geocoded, neighborhoods were defined using 800 m radial buffers, and variables representing neighborhood socioeconomic deprivation, social disorder, walkability, and greenness were created. Psychological distress (anxiety and depression symptoms) and proposed pathway variables chronic stress, social support, and family cohesion were assessed at HCHS/SOL Visit 2 (2014-2017).

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Interpersonal management of homophobic stigma (e.g., selectively constructing one's social network; confronting stigma) is an understudied area of resilience among sexual minority people.

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Article Synopsis
  • Ocular predominant mucous membrane pemphigoid (oMMP) is a severe condition that can lead to scarring and blindness; diagnosing it is challenging due to a high false-negative rate (up to 40%) in conjunctival biopsies that use direct immunofluorescence (DIF).
  • Serologic testing offers a less invasive diagnostic method but often shows low levels of autoantibodies in oMMP patients, making it less reliable.
  • The autoantigens involved, like integrin β4 and BP180, have shown mixed results in their specificity for diagnosing oMMP, prompting a need for better understanding and improvement in serological diagnostic approaches.
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