201 results match your criteria: "Chicago Center for HIV Elimination[Affiliation]"

Sexually minoritized men (SMM), transgender women (TW), and particularly Black SMM and Black TW may be disproportionately impacted by alcohol-related problems. Few studies have empirically examined neighborhood factors that may contribute to alcohol use, specifically among these populations. Using data from the N2 longitudinal cohort study in Chicago, IL, survey data from the second wave of longitudinal assessment (n = 126) and GPS mobility data from enrollment were used to evaluate neighborhood alcohol outlet availability, neighborhood disorder, and neighborhood poverty as correlates of individual alcohol use.

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Background: People living with mental illness (PLWMI) experience a disproportionate prevalence and incidence of HIV. Preventing HIV among PLWMI is a priority for multiple domestic public health agencies. As key clinicians for this group, psychiatrists may have an important role to play in increasing PrEP use among PLWMI.

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Agent-Based Model of Combined Community- and Jail-Based Take-Home Naloxone Distribution.

JAMA Netw Open

December 2024

Decision and Infrastructure Sciences Division, Argonne National Laboratory, Lemont, Illinois.

Importance: Opioid-related overdose accounts for almost 80 000 deaths annually across the US. People who use drugs leaving jails are at particularly high risk for opioid-related overdose and may benefit from take-home naloxone (THN) distribution.

Objective: To estimate the population impact of THN distribution at jail release to reverse opioid-related overdose among people with opioid use disorders.

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Introduction: Recovery support workers (RSWs) who provide social support interventions for people who use drugs (PWUD) often face challenges that can jeopardize the well-being, efficacy and sustainability of this essential workforce. To date, little has been reported on the types of implementation strategies used to support RSWs. We describe and evaluate a multifaceted implementation strategy package to support Reducing Opioid Mortality in Illinois (ROMI), a paired peer recovery coach and case manager (PRC-CM) intervention for PWUD with recent criminal-legal involvement in urban and rural settings.

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Article Synopsis
  • Rates of congenital syphilis (CS) have significantly increased in the U.S., with limited research on the experiences of affected birthing parents and prenatal providers in Chicago and the Midwest.
  • Semistructured interviews and retrospective data were collected from birthing parents of infants with CS and their prenatal providers to understand factors contributing to the rise in cases.
  • Identified barriers included inadequate access to treatment, poor communication, lack of patient knowledge, and stigma, highlighting the complex challenges in the syphilis care continuum.
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Social support has been associated with viral suppression among persons living with HIV (PWH). We examined cross-sectional data from young Black men who have sex with men to see if sociodemographic factors, medical history, and egocentric Facebook social support measures are related to viral suppression. Differences between participants were examined using Chi-square, Fisher's exact, or Wilcoxon Rank Sum Tests, with significance set at = 0.

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Background: The Ryan White Medical Case Management System, which serves more than half of people living with HIV (PLWH) in the USA, is an opportune setting for identifying and addressing depression among PLWH. A growing body of research suggests that interventions that promote positive emotion may lessen symptoms of depression and improve physical and psychological well-being among people experiencing a variety of health-related stress, including living with HIV. Research on how best to integrate standardized mental health screening and referral to evidence-based interventions in Ryan White Medical Case Management settings has the potential to improve the health and wellbeing of PLWH.

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Accessibility of Naloxone in Pharmacies Registered Under the Illinois Standing Order.

West J Emerg Med

July 2024

University of Chicago, Department of Medicine, Section of Infectious Diseases and Global Health, Chicago, Illinois.

Introduction: To expand access to naloxone, the state of Illinois implemented a standing order allowing registered pharmacies to dispense the drug without an individual prescription. To participate under the standing order, pharmacies were required to opt in through a formal registration process. In our study we aimed to evaluate the availability and price of naloxone at registered pharmacies.

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Purpose: HIV biomedical intervention uptake is suboptimal among Black sexually minoritized men (SMM) and transgender women (TW). Venues where people meet and interact shape HIV-related risk and prevention behaviors. We aimed to construct GPS-defined venue-based affiliation networks and identify the unique set of venues that could maximize reach of HIV biomedical interventions among Black SMM and TW.

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Introduction: Young sexual minority men (SMM) bear the greatest burden of anal human papillomavirus (HPV) infections. We assessed anal HPV genotype discordance between the Linear Array (LA) and SPF10 PCR-DEIA-LiPA25 (LiPA25).

Methods: Discordance was assessed between LA and LiPA25 using self-collected anal swabs from 120 SMM aged 18-29 who were recruited in 2014-2016.

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Electronic patient portals represent a promising means of integrating mental health assessments into HIV care where anxiety and depression are highly prevalent. Patient attitudes toward portal-based mental health screening within HIV clinics have not been well described. The aim of this formative qualitative study is to characterize the patient-perceived facilitators and barriers to portal-based anxiety and depression screening within HIV care in order to inform implementation strategies for mental health screening.

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Background: Long-acting injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) offers a novel drug delivery option for persons with human immunodeficiency virus (PWH) but requires administration every 4 or 8 weeks by a medical professional.

Methods: To facilitate LAI antiretroviral therapy (ART) scale-up, we evaluated patient interest in alternative administration approaches via a mixed-methods, serial cross-sectional study across 3 US HIV clinics. We surveyed PWH (December 2021 to May 2022) on appeal of self- or partner/friend/family-administered LAI-CAB/RPV; multivariable ordinal logistic regression explored associated characteristics.

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Transgender women of color (TWOC) experience high rates of police violence and victimization compared to other sexual and gender minority groups, as well as compared to other White transgender and cisgender women. While past studies have demonstrated how frequent police harassment is associated with higher psychological distress, the effect of neighborhood safety and neighborhood police violence on TWOC's mental health is rarely studied. In this study, we examine the association between neighborhood safety and neighborhood police violence with psychological distress among TWOC.

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Preexposure Prophylaxis (PrEP) for HIV Prevention at Outpatient Substance Use Treatment Facilities, United States, 2021.

Am J Public Health

August 2024

Samuel Bunting is with the Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL. Nitin Vidyasagar is with the Pritzker School of Medicine, University of Chicago. Allison Wilson and Aniruddha Hazra are with the Chicago Center for HIV Elimination, University of Chicago. Aniruddha Hazra is also with the Section of Infectious Diseases, Department of Medicine, University of Chicago.

To determine the percentage of US outpatient substance use treatment facilities that offer HIV preexposure prophylaxis (PrEP). We used a retrospective cross-sectional design with data from the National Substance Use and Mental Health Services Survey, which was administered to directors of US outpatient substance use treatment facilities in 2021. We evaluated the percentage of outpatient substance use treatment facilities offering PrEP and factors associated with the likelihood of offering PrEP.

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Article Synopsis
  • - The study investigates how exposure to violent and property crime affects HIV prevention and care outcomes for Young Black Sexually Minoritized Men (YBSMM) and Transgender Women (TGW), who are at high risk for HIV.
  • - Using GPS technology, researchers analyzed the activity spaces of 286 individuals in Chicago to find links between crime exposure and various HIV-related outcomes, including PrEP use.
  • - Results showed that individuals in higher-crime areas were significantly less likely to use PrEP for HIV prevention, highlighting crime as a potential barrier to healthcare access for these vulnerable groups.
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Understanding the acceptability of long-acting injectable antiretroviral therapy (LAI-ART) among people with HIV (PWH), especially priority populations, is essential for effective implementation. We conducted semi-structured interviews with patients in three Ryan White-funded HIV clinics in San Francisco, Chicago, and Atlanta. We employed maximal variation sampling across age, gender, race, ethnicity, and time living with HIV and oversampled for individuals with suboptimal clinical engagement.

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Introduction: Bacterial vaginosis (BV) is associated with non-optimal changes in the vaginal microbiome and increased susceptibility to STIs and HIV in cisgender women. Much less is known about the sexual health of transmasculine people and susceptibility to BV, STIs, and HIV. This study's objective was to assess BV testing and outcomes of transmasculine and cisgender women patient populations at a large, LGBTQ + federally qualified health center.

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Health equity for Black sexually minoritised men through status-neutral HIV care.

Lancet HIV

April 2024

Section of Infectious Diseases & Global Health, Department of Medicine, University of Chicago, Chicago, IL, USA; Chicago Center for HIV Elimination, University of Chicago, Chicago, IL, USA; Department of Public Health Sciences, University of Chicago, Chicago, IL, USA.

Current strategies (both biomedical and barrier methods) for HIV elimination in the USA do not best serve those who are most affected by HIV. Improving healthc are for individuals most affected by HIV requires restructuring of care delivery to improve their HIV outcomes. The transformation of clinical care delivery is crucial to address the needs of one of the most affected populations along the HIV care continuum: Black sexually minoritised men (BSMM).

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Accurate, timely human immunodeficiency virus (HIV) diagnosis is critical. Routine HIV screening program data were examined before and after reflex HIV type 1 RNA testing. Reflex testing facilitated confirmation of reactive HIV screening assays (as true or false positives) (odds ratio, 23.

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Background: Sex workers, those who trade sex for monetary or nonmonetary items, experience high rates of HIV transmission but have not been adequately included in HIV prevention and Pre-Exposure Prophylaxis (PrEP) adherence program development research. Community-empowered (C.E.

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Article Synopsis
  • Black cisgender gay, bisexual, and other sexual minority men (SMM) and transgender women (TW) are disproportionately impacted by HIV, highlighting the need for more research focused on the effects of substance use and sleep health in this demographic.* -
  • The N2 Part 2 (N2P2) study builds on the original Neighborhoods and Networks (N2) study, aiming to identify socioenvironmental factors that influence HIV prevention and treatment in Black SMM and TW across Chicago.* -
  • Utilizing a longitudinal cohort design, N2P2 will engage 600 participants over 18 months, collecting various data types to assess neighborhood influences and factors like substance use and sleep on health outcomes.*
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Background: Stigma contributes to health disparities including increased HIV vulnerability among minority communities. Black transgender women experience multiple forms of stigma (e.g.

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Article Synopsis
  • Long-acting injectable antiretroviral therapy (LAI-ART) is the latest development in HIV treatment, requiring research to improve access for all individuals living with HIV.
  • Focus group discussions were held with healthcare providers in major US cities to identify barriers and facilitators for implementing LAI-ART, emphasizing organizational readiness and participant insights.
  • Key findings showed a strong commitment to equitable access to LAI-ART, the need for clinics to take on more responsibility for patient adherence, and highlighted the importance of strengthening existing systems and resources to facilitate broader implementation.
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Experiences of stigma in health care encounters among LGBTQ+ populations (lesbian, gay, bisexual, transgender, and queer and questioning) have long been a barrier to care. Marginalization and historically grounded fears of stigmatization have contributed to a reluctance to disclose sexual behavior and/or gender identity to health care providers. We reflect on how student nurses grappled with the ethics of patient disclosure while providing mobile outreach in Chicago for mpox (formerly monkeypox) from fall 2022 to spring 2023.

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While rare in the larger population, anal cancer incidence is significantly higher in groups such as sexual minority men and people living with HIV. This qualitative analysis examined participants' experiences and perceptions of barriers to anal self-examination and anal companion examination through interviews completed as a part of a larger clinical trial. Interviews were conducted online with participants ( = 131) within a week of their baseline appointment between January 2020 and October 2021.

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