4 results match your criteria: "Chengdu University of Traditional Chinese Medicine Chengdu 611130[Affiliation]"
[Assay of amino acids in leaves of Eucommia ulmoides under arbor forest mode and leaf-oriented cultivation mode by pre-column derivatization HPLC].
Zhongguo Zhong Yao Za Zhi
April 2023
State Key Laboratory of Southwest Characteristic Traditional Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611130, China.
This study aims to develop the pre-column derivatization high performance liquid chromatography(HPLC) method for the determination of 16 kinds of amino acids in Eucommia ulmoides leaves, and compare the content of amino acids in the leaves harvested at different time and under leaf-oriented cultivation mode(LCM) and arbor forest mode(AFM). The HPLC conditions are as below: phenyl isothiocyanate(PITC) as pre-column derivatization agent, Agilent ZORBAX C_(18 )column(4.6 mm×250 mm, 5 μm), mobile phase A of acetonitrile-water(80∶20), mobile phase B of 0.
View Article and Find Full Text PDF[Study on metabolites in vivo of Dangefentong Capsules based on UHPLC-Q/Orbitrap-MS/MS].
Zhongguo Zhong Yao Za Zhi
September 2022
Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia Medica,Sichuan Academy of Chinese Medicine Sciences Chengdu 610041, China School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611130, China.
Article Synopsis
- Dangefentong Capsules are a new traditional Chinese medicine aimed at treating diabetic peripheral neuropathy, combining key herbs Salviae Miltiorrhizae and Puerariae Lobatae with active components like salvianolic acids and flavonoids.
- A study used UHPLC-Q/Orbitrap-MS/MS technology to analyze the capsules' chemical composition and metabolites in Beagle dogs, focusing on their presence in plasma, urine, and feces after administration.
- The analysis identified 107 chemical components, including 58 prototypes and 49 metabolites, revealing metabolic transformations such as methylation and hydroxylation, which will help understand the capsules' pharmacodynamic mechanisms.
[Content determination of phenolic acids in fresh Salvia miltiorrhiza and effect of polyphenol oxidase on content].
Zhongguo Zhong Yao Za Zhi
March 2021
Sichuan Provincial Key Laboratory of Quality and Innovation Research of Chinese Materia,Sichuan Academy of Chinese Medicine Sciences Chengdu 610041, China School of Pharmacy of Chengdu University of Traditional Chinese Medicine Chengdu 611130,China.
There is no consensus on the content, accumulation, transformation and content determination methods of phenolic acids in fresh Salvia miltiorrhiza. In order to find out the true content of phenolic acids in fresh S. miltiorrhiza, a variety of treatment me-thods were used in this study to prepare sample solution.
View Article and Find Full Text PDF[Research progress on production districts of Sichuan Dao-di herbs].
Zhongguo Zhong Yao Za Zhi
February 2020
Dao-di herbs are the Chinese herbs which have high quality and best clinic effects. Sichuan is one of the proviences most rich in Chinese herb resources,which has 7 290 species of Chinese herbs, such as Curcumae Longae Rhizoma, Chuanxiong Rhizoma, Aconiti Lateralis Radix Praeparata, Ophiopogonis Radix, Coptidis Rhizoma, Gentianae Radix, Rhei Radix et Rhizoma, Curcumae Rhizoma, Gardeniae Fructus, ect. After textual research on materia medica of the 7 290 Chinese herbs, we find there are 86 Dao-di herbs in Sichuan, such as Chuanxiong Rhizoma from Dujiangyan, Aconiti Lateralis Radix Praeparata from Jiangyou, Fritillariae Radix, Notoptergii Rhizoma et Radix, Angelicae Dahuricae Radix from Suining, Ophiopogonis Radix from Santai, Salviae Miltiorrhizae Radix et Rhizoma from Zhongjiang, Magnoliae Officinalis Cortex from Pingwu.
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