2 results match your criteria: "Chengdu University of Traditional Chinese Medicine Chengdu 611100[Affiliation]"
[Experimental research progress in traditional Chinese medicine prevention and treatment of diabetic peripheral neuropathy based on autophagy].
Zhongguo Zhong Yao Za Zhi
December 2023
School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine Chengdu 611100, China.
Diabetic peripheral neuropathy(DPN) is a chronic complication resulted from peripheral nerve injury in the late stage of diabetes. It involves a variety of pathological changes such as oxidative stress, endoplasmic reticulum stress, neuroinflammation, and apoptosis of Schwann cells(SCs). DPN is the main factor leading to lower limb disability or amputation in diabetic patients, with high incidence, long disease course, and poor prognosis.
View Article and Find Full Text PDF[Mechanism of Huanglian Houpo Decoction in treatment of ulcerative colitis in mice based on brain-gut axis].
Zhongguo Zhong Yao Za Zhi
June 2022
School of Pharmacy, Chengdu University of Traditional Chinese Medicine Chengdu 611100,China.
Article Synopsis
- The study examined the effects of Huanglian Houpo Decoction (HLHPD) on ulcerative colitis by focusing on the brain-gut axis and the regulation of neurotransmitters like 5-HT, SP, and VIP in mice.
- Sixty male mice were divided into groups, with one group receiving a model for UC and others being treated with varying doses of HLHPD or a known medication (sulfasalazine) over ten days.
- Results showed that HLHPD improved colitis symptoms by increasing body weight, reducing inflammation markers, and altering neurotransmitter levels, suggesting its potential as a treatment for UC.