53 results match your criteria: "Chengdu Medical College Chengdu[Affiliation]"
Characterization of carbapenem-resistant Acinetobacter baumannii isolates in a Chinese teaching hospital.
Front Microbiol
September 2015
Small Molecule Drugs Sichuan Key Laboratory, Institute of Materia Medica, Chengdu Medical College Chengdu, China.
Article Synopsis
- Carbapenem-resistant Acinetobacter baumannii (CRAB) poses significant challenges in treatment and infection control, particularly in a hospital in western China.
- A study examined 110 clinical isolates, revealing that 60.9% were resistant to carbapenems and most (80.60%) carried the bla OXA-23 gene, primarily belonging to clone complex 92 (CC92).
- The research highlights the need for careful antibiotic use to combat the increase of CRAB infections and drug resistance spread.
Casitas B-Lineage Lymphoma RING Domain Inhibitors Protect Mice against High-Fat Diet-Induced Obesity and Insulin Resistance.
PLoS One
May 2016
Department of Pharmacy, Chengdu Medical College. Chengdu, Sichuan Province, China.
The casitas b-lineage lymphoma (c-Cbl) is an important adaptor protein with an intrinsic E3 ubiquitin ligase activity that interacts with E2 proteins such as UbCH7. c-Cbl plays a vital role in regulating receptor tyrosine kinase signaling. c-Cbl involves in whole-body energy homeostasis, which makes it a potential target for the treatment of type 2 diabetes and obesity.
View Article and Find Full Text PDFLoss of expression of MHC class I-related chain A (MICA) is a frequent event and predicts poor survival in patients with hepatocellular carcinoma.
Int J Clin Exp Pathol
May 2015
State Key Laboratory of Cancer Biology, Experimental Teaching Center of Basic Medicine, Fourth Military Medical University Xi'an 710032, China.
Natural killer (NK) cells are important effector cells for the first line of defense against tumor. Distant MHC class I homolog MICA has been identified as human ligand for NK cell activating receptor NKG2D. Engagement of MICA triggers NK cells and augments antigen-specific CTL anti-tumor immunity.
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