117 results match your criteria: "Chengde Central Hospital.[Affiliation]"

LncRNA EBLN3P attributes methotrexate resistance in osteosarcoma cells through miR-200a-3p/O-GlcNAc transferase pathway.

J Orthop Surg Res

December 2022

Department of Orthopaedics, Chengde Central Hospital, No. 11 Guangren Street, Shuangqiao District, Chengde, 067000, Hebei, China.

Article Synopsis
  • * The study measured EBLN3P levels in osteosarcoma tissues based on their response to methotrexate (MTX) and established MTX-resistant cell lines to investigate related targets and pathways through bioinformatics.
  • * Results showed that higher EBLN3P levels correlate with MTX resistance; targeting EBLN3P reduces resistance by impacting the microRNA miR-200a-3p and its target, O-
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Introduction: There is a dearth of comprehensive studies on the association between serum electrolyte and adverse short-term prognosis of Chinese patients with acute decompensated heart failure (ADHF).

Patients And Methods: A total of 5166 patients with ADHF were divided into four serum electrolyte-related study populations (potassium ( = 5145), sodium ( = 5135), chloride ( = 4966), serum total calcium (STC) ( = 4143)) under corresponding exclusions. Different logistic regression models were utilized to gauge the association between these electrolytes or the number of electrolyte abnormalities and the risk of a composite of all-cause mortality or 30-day heart failure (HF) readmission.

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Objective: To assess the effect of long-term nursing intervention on the quality of life and social support of patients after percutaneous coronary intervention (PCI).

Methods: A randomised controlled trial was designed. A total of 60 patients with coronary heart disease treated with PCI were randomly divided into the control group and the intervention group.

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Background: Verruca plana is a benign proliferation of the skin caused by human papilloma virus (HPV) infection. Fresh garlic can serve as an alternative therapy, and it has shown considerable effectiveness as a topical treatment for verruca plana. However, topical garlic treatment for verruca plana triggered Koebner phenomenon (KP), which has not been previously reported.

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Background: Cri du chat syndrome (CdCS), also known as 5p deletion syndrome (5p-) is a syndrome caused by partial deletion of the 5p chromosome in human beings. The incidence accounts for 1/50000 and the cause of CdCS is related to partial deletion of chromosome 5 short arm (p). CdCS is a sporadic event.

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SRRM1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the JAK/STAT signaling pathway.

Tissue Cell

December 2022

Cardiothoracic Interventional Vascular Surgery, Chengde Central Hospital, Chengde, Hebei 067000, China. Electronic address:

Background: To explore the regulatory effect of serine/arginine repetitive matrix 1 (SRRM1) on hepatocellular carcinoma (HCC) and its potential pathway.

Methods: SRRM1 level in the tissue was tested by western blot and immunohistochemistry. Cells proliferation, apoptosis, migration, and invasion were tested by EdU, flow cytometry, wound healing assay, and Transwell, respectively.

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Background: There is scant data on the association of the Pulsed wave-Doppler tissue imaging (PW-DTI)-derived tricuspid lateral annular peak systolic velocity (S') and poor short-term prognosis of patients with acute decompensated heart failure (ADHF).

Patients And Methods: A total number of 732 participants from the Heb-ADHF registry in China were divided into three groups according to the corresponding status of tricuspid S'. Demographic characteristics, comorbidities, physical examinations, lab tests, and medications were compared among the different groups.

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Ectopic papillary thyroid carcinoma mimicking distant metastatic tissue.

J Int Med Res

September 2022

Deparatment of Medical Imaging, Chengde Central Hospital, No. 11 Guangren Road, Chengde, Hebei, People's Republic of China.

We report a case of a 50-year-old woman presenting with a solid nodule in each lung. She was previously suspected of having lung cancer and distant pulmonary metastasis on the basis of imaging findings. Surgical pathology revealed that the left lung nodule was adenocarcinoma, but the contralateral nodule was papillary thyroid carcinoma (PTC).

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Background: Intracranial atherosclerotic stenosis (ICAS) is one of the leading causes of stroke worldwide. Current diagnostic evaluations and treatments remain insufficient to assess the vulnerability of intracranial plaques and reduce the recurrence of stroke in symptomatic ICAS. On the other hand, asymptomatic ICAS is associated with an increased risk of cognitive impairment.

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Objectives: To evaluate the clinical efficacy of early postoperative intensity-modulated radiotherapy (IMRT) combined with temozolomide chemotherapy in the treatment of patients with malignant glioma.

Methods: In this retrospective cohort study 80 patients with glioma surgery admitted to Chengde Central Hospital from January 2019 to January 2021 were selected and divided into two groups according to postoperative treatment: the experimental group and the control group, with 40 cases in each group. Patients in the experimental group received IMRT combined with temozolomide chemotherapy postoperatively, while those in the control group received IMRT alone.

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Objective: To analyze the risk factors for osteochondral fracture (OCF) of first-time acute patellar dislocation (APD) through measurements of patellofemoral anatomy in adolescents.

Methods: In this prospective study, all patients were divided into two groups according to whether OCF was detected on magnetic resonance imaging (MRI): Group A (associated with OCF) and Group B (without OCF). Patellofemoral anatomy was evaluated with four aspects including trochlear/patellar dysplasia, patella location, patellofemoral matching, and morphologic classification.

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Annular rupioid secondary syphilis confined to the face.

Int J Infect Dis

September 2022

Department of Dermatology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei Province, 063000, China. Electronic address:

Objectives: Syphilis is a sexually transmitted infection (STI) caused by treponema pallidum. Its rash usually affects the trunk and limbs extensively, including the palms and soles of the feet. Secondary syphilis confined to the face is extremely rare.

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Validation and derivation of short-term prognostic risk score in acute decompensated heart failure in China.

BMC Cardiovasc Disord

July 2022

First Division, Department of Cardiology, The Second Hospital of Hebei Medical University, Heping West Road No. 215, Shijiazhuang, 050000, Hebei province, China.

Background: Few prognostic risk scores (PRSs) have been routinely used in acute decompensated heart failure (ADHF). We, therefore, externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new PRS to predict the short-term prognosis in ADHF.

Methods: A total of 4550 patients from the Heb-ADHF registry in China were randomly divided into the derivation and validation cohorts (3:2).

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Background: Elderly patients tend to have poor self-efficacy and poor confidence in postoperative rehabilitation for hip fractures, and are prone to negative emotions, which affect treatment compliance.

Aim: To evaluate the effects of evidence-based intervention on postoperative fear, compliance, and self-efficacy in elderly patients with hip fractures.

Methods: A total of 120 patients with hip fracture surgically treated from June 2018 to June 2020 at the orthopedic department of our hospital were selected and divided into intervention and routine groups ( = 60 each) according to different nursing methods.

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Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats.

Open Life Sci

March 2022

Department of Osteology, Chengde Central Hospital, Guangren Street, Chengde City, Hebei Province 067000, China.

The aim of the study was to investigate the inhibitory effect of hydroxysaff yellow A (HSYA) on diabetic retinopathy (DR). For this, a total of 27 rats were randomly divided into normal control, model, and HSYA groups. The body weight, blood glucose, and blood-retinal barrier damage of the rats were observed and compared.

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Background: The efficacy of ethiodized poppyseed oil in hysterosalpingography (HSG) image quality and fertility enhancement has been revealed, but whether this HSG modality has similar effects in the Chinese population is still unclear.

Methods: Between July 18, 2017, and December 29, 2019, this multicentric, randomized, two-arm, clinical trial was performed involving 15 medical centers. Infertile women meeting HSG indications were randomly assigned to an oil group and a water group.

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Article Synopsis
  • Oxidative stress from a lack of blood flow can damage the kidneys and cause a problem called acute kidney injury (AKI).
  • A study showed that a drug called sevoflurane (SEV) can help protect the kidneys from this damage by improving how the body fights off stress and inflammation.
  • When sevoflurane was given before kidney injury, it helped reduce harmful substances in the blood and activated a protein called Nrf2, which is important for keeping the kidneys healthy.
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Estrogen receptor 1 (ESR1) XbaI polymorphisms may affect breast cancer susceptibility; however, the results of previously published studies are inconsistent. This meta-analysis aimed to investigate the relationship between ESR1 XbaI polymorphism and breast cancer risk.  Methods: Articles from the PubMed, Embase, Cochrane Library, WoS, Scopus, Wanfang Data, CNKI, CBM and CQVIP databases were systematically searched to determine the association between ESR1 XbaI polymorphism and breast cancer risk.

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Objective: Tracheal intubation under general anesthesia is more likely to aggravate the injury of the cervical spine and spinal cord. We aim to explore the effect of dexmedetomidine combined with intubating laryngeal mask airway (ILMA) on anesthesia and stress response in patients with a cervical spine injury.

Patients And Methods: One hundred twenty patients were retrospectively allocated into the control group (midazolam + ILMA) and intervention group (dexmedetomidine + ILMA).

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Night shift is a common work schedule. This study aimed to analyze the interaction between age and frequency of night shift on the hypertension prevalence. A census questionnaire was conducted in 512 medical institutions in 11 cities of Hebei Province.

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Background: Little is known about the biomechanical performance of different internal fixations in oblique lumbar interbody fusion (OLIF). Here, finite element (FE) analysis was used to describe the biomechanics of various internal fixations and compare and explore the stability of each fixation.

Methods: CT scans of a patient with lumbar degenerative disease were performed, and the l3-S1 model was constructed using relevant software.

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