A levy chaotic horizontal vertical crossover based artificial hummingbird algorithm for precise PEMFC parameter estimation.

In this research, enhanced versions of the Artificial Hummingbird Algorithm are used to accurately identify unknown parameters in Proton Exchange Membrane Fuel Cell (PEMFC) models. In particular, we propose a multi strategy variant, the Lévy Chaotic Artificial Hummingbird Algorithm (LCAHA), which combines sinusoidal chaotic mapping, Lévy flights and a new cross update foraging strategy. The combination of this method with PEMFC parameters results in a significantly improved performance compared to traditional methods, such as Particle Swarm Optimization (PSO), Differential Evolution (DE), Grey Wolf Optimizer (GWO), and Sparrow Search Algorithm (SSA), which we use as baselines to validate PEMFC parameters.

Precision parameter estimation in Proton Exchange Membrane Fuel Cells using depth information enhanced Differential Evolution.

Proton Exchange Membrane Fuel Cell (PEMFC) models require parameter tuning for their design and performance improvement. In this study, Depth Information-Based Differential Evolution (Di-DE) algorithm, a novel and efficient metaheuristic approach, is applied to the complex, nonlinear optimization problem of PEMFC parameter estimation. The Di-DE algorithm was tested on twelve PEMFCs (BCS 500 W PEMFC, Nedstack 600 W PS6 PEMFC, SR-12 500 W PEMFC, H-12 PEMFC, STD 250 W PEMFC, HORIZON 500 W PEMFC and four 250W PEMFC and two H-12 12W PEMFC) and showed excellent accuracy.

Non-invasive Assessment of Liver Fibrosis Using Shear Wave Elastography in Patients With Type 2 Diabetes Mellitus Having Non-alcoholic Fatty Liver Disease.

Background  Type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) frequently coexist due to overlapping risk factors such as metabolic syndrome and obesity. T2DM exacerbates the progression of NAFLD, increasing the risk of cirrhosis and hepatocellular carcinoma. Thus, early detection of liver fibrosis is crucial to prevent severe liver disease.

Coefficient-Shuffled Variable Block Compressed Sensing for Medical Image Compression in Telemedicine Systems.

Medical professionals primarily utilize medical images to detect anomalies within the interior structures and essential organs concealed by the skeletal and dermal layers. The primary purpose of medical imaging is to extract image features for the diagnosis of medical conditions. The processing of these images is indispensable for evaluating a patient's health.

Larvicidal and enzyme inhibition effects of Phoenix pusilla derived Methyl oleate and malathion on Aedes aegypti strains.

This study explores the larvicidal potential of methanolic flower extracts from Phoenix pusilla (Pp-Fe), its major compound, and malathion (MLT), against laboratory strain (LS) and field strain (FS) of Aedes aegypti, the dengue mosquito vector. We identified thirty-one derivatives, with methyl oleate (MO) comprising 28.5% of Pp-Fe.

Metagenomics approaches in the discovery and development of new bioactive compound of 8-demethoxy-10-deoxysteffimycin from mangrove sediments.

A metagenomic library consisting of 15,000 clones was constructed from the mangrove sediment. An antimicrobially active clone from the metagenomic library PS49 was identified by function- based screening. This paper presents the results of the biochemical characterization and metagenomic library screening of the marine-derived antibiotic, 8-demethoxy-10-deoxysteffimycin.

A hybrid mutational Northern Goshawk and elite opposition learning artificial rabbits optimizer for PEMFC parameter estimation.

For the purpose of simulating, controlling, evaluating, managing and optimizing PEMFCs it is necessary to develop accurate mathematical models. The present study develops a mathematical model which uses empirical or semi-empirical equations to estimate unknown model parameters through optimization techniques. This thesis calculates, analyzes and discusses the sum of squares error (SSE) between measured and estimated current and voltage values using parameters derived from multiple optimization techniques for six commercially available PEMFCs: BCS 500 W-PEMFC, 500 W SR-12 PEMFC, Nedstack PS6 PEMFC, H-12 PEMFC, HORIZON 500 W PEMFC and a 250 W-stack PEMFC.

Perceived Stress Among Private School Teachers in Chengalpattu District, Tamil Nadu, India: A Cross-Sectional Study.

Background Teachers are the cornerstone of any civilized society, preserving knowledge, wisdom, and ideals. Along with job-related stress, teachers face a variety of challenging circumstances in the classroom. This includes thoughts concerning a lack of professional appreciation, challenges maintaining classroom discipline, a lack of peer support, and extra duties like surveys and government mandates.

Neonatal Encephalopathy due to Glutaminase Deficiency in a Neonate.

Identifying neurometabolic disorders that lead to neonatal encephalopathy is difficult, and access to exome sequencing is a significant advantage in developing countries. We present a case of neonatal encephalopathy characterized by refractory seizures and significant apnea resulting from glutaminase deficiency, along with elevated levels of glutamine and glycine in the cerebrospinal fluid. Although the condition was fatal, it was possible to offer genetic counseling and recommendations for future pregnancies following exome sequencing.

Analysis of Immunohistochemical Expression of Bcl-2 in Cases of Psoriasis and Psoriasiform Dermatitis.

Introduction Psoriasis involves rapid cell growth and abnormal differentiation of skin cells. Dysregulation of apoptosis has been proposed in the pathogenesis of psoriasis. The role of Bcl-2 as an anti-apoptotic protein in pathogenesis has not been studied in detail in these cases.

Multifaceted evaluation of pyrazole derivative (T4)-chitosan (CS) nanoparticles: Morphology, drug release, and anti-tumor efficacy in a rat model.

The development of targeted nanotherapeutics has emerged as a pivotal advancement in cancer treatment, aiming to enhance the efficacy and specificity of drug delivery while minimizing systemic toxicity. Due to their biocompatibility and modifiable surface properties, Chitosan-based nanoparticles have shown considerable promise in encapsulating and delivering therapeutic agents directly to tumor sites. This study investigates the potential of 1,5-diary pyrazole derivative (T4)-loaded chitosan (CS) nanoparticles as a novel anticancer agent, evaluating their physical characteristics, in vivo biodistribution, and therapeutic efficacy against cancerous cells.

Formulation of Asiatic acid-loaded polymeric chitosan-based hydrogel for effective MRSA infection control and enhanced wound healing in zebrafish models.

Background: Wound healing relies on a controlled inflammatory process vital for tissue regeneration. Chronic wounds, characterized by persistent inflammation and high infection risk, pose significant challenges in healthcare. Hydrogel dressings offer promise in wound care; however, the understanding of their role in managing inflammation and infection remains unclear.

1,5- diaryl pyrazole-loaded chitosan nanoparticles as COX-2 inhibitors, mitigate neoplastic growth by regulating NF-κB pathway in-vivo zebrafish model.

Non-steroidal anti-inflammatory drugs (NSAIDs) have been researched for their capacity to reduce cancer incidence, primarily due to their COX-2 inhibition properties. However, concerns have arisen regarding the precision of their targeting abilities. Nanoparticle approaches are revolutionizing cancer treatment by enabling targeted drug delivery, which enhances the efficacy and reduces the toxicity of chemotherapy.

Unraveling Facial Nerve Palsy: A Case Series Highlighting Diagnostic and Therapeutic Challenges.

Facial nerve palsy (FNP) may arise from multiple etiological reasons, including anatomical anomalies, circulatory complications, and infectious agents. This case series underscores the importance of a comprehensive diagnostic approach to identify the precise etiology, including structural abnormalities, vascular anomalies, or infectious illnesses. Here, we present three distinct occurrences of FNP, emphasizing the varied diagnostic difficulties and therapeutic strategies.

A combinational threat of micro- and nano-plastics (MNPs) as potential emerging vectors for per- and polyfluoroalkyl substances (PFAS) to human health.

Micro- and nano-plastics (MNPs) and per- and polyfluoroalkyl substances (PFAS) are prevalent in ecosystems due to their exceptional properties and widespread use, profoundly affecting both human health and ecosystem. Upon entering the environment, MNPs and PFAS undergo various transformations, such as weathering, transport, and accumulation, potentially altering their characteristics and structural dynamics. Their interactions, governed by factors like hydrogen bonding, hydrophobic interactions, Van der Waals forces, electrostatic attractions, and environmental conditions, can amplify or mitigate their toxicity toward human health within ecological conditions.

Classification and bibliometric analysis of hydrogels in periodontitis treatment: Trends, mechanisms, advantages, and future research directions.

Objectives: The review assess the potential of hydrogel-based drug delivery systems in treating periodontitis. Hydrogels are classified based on source, composition, configuration, crosslinking methods, ionic charge, and response to stimuli.

Methods: The methodology comprised of comprehensive data collection from WoS, Scopus and PubMed databases covering the period of 2004-2024 of 626 documents.

Exploring the epidemiology and awareness of metabolic dysfunction-associated steatotic liver disease (MASLD) among health sciences students in an academic health care institute in India.

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 25 % of the global population, presenting a significant health challenge. It is often asymptomatic but linked to severe conditions like cirrhosis and liver cancer. Previous research indicates that people often underestimate MASLD risks.

Carbamazepine-induced Stevens-Johnson Syndrome: A Case Report with Review of the Literature.

Background: Stevens-Johnson Syndrome (SJS) is an infrequent yet severe mucocutaneous reaction that involves less than 10% of the Body Surface Area (BSA). It is predominantly induced by certain medications, including anticonvulsants (e.g.

Neurocognitive effects of proanthocyanidin in Alzheimer's disease: a systematic review of preclinical evidence.

Cognitive disorders and dementia largely influence individual independence and orientation. Based on the Alzheimer's Disease International (ADI) estimation, approximately 75% of individuals with dementia are undiagnosed. In fact, in some low- and middle-income countries, the percentage is as high as 90%.