One-pot synthesis at room temperature of epoxides and linalool derivative pyrans in monolacunary NaPWO-catalyzed oxidation reactions by hydrogen peroxide.

In this work, we describe a new one-pot synthesis route of valuable linalool oxidation derivatives (, 2-(5-methyl-5-vinyltetrahydrofuran-2-yl propan-2-ol) (1a)), 2,2,6-trimethyl-6-vinyltetrahydro-2-pyran-3-ol (1b) and diepoxide (1c), using a green oxidant (, hydrogen peroxide) under mild conditions (, room temperature). Lacunar Keggin heteropolyacid salts were the catalysts investigated in this reaction. Among them, NaPWO was the most active and selective toward oxidation products.