4 results match your criteria: "Chelsea and Westminster Hospital Trust[Affiliation]"

Drain placement in paediatric complicated appendicitis: a systematic review and meta-analysis.

Pediatr Surg Int

April 2023

Department of Paediatric Surgery, Chelsea Children's Hospital, Chelsea and Westminster Hospital Trust, London, UK.

Children undergoing appendicectomy for complicated appendicitis are at an increased risk of post-operative morbidity. Placement of an intra-peritoneal drain to prevent post-operative complications is controversial. We aimed to assess the efficacy of prophylactic drain placement to prevent complications in children with complicated appendicitis.

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Background: We investigated the reasons for switching antiretroviral regimens, an issue rarely addressed in cohort studies.

Methods: An observed toxicity switch rate (OTSR) was calculated by Poisson regression using the number of days individuals received each individual antiretroviral drug.

Results: Of 3333 individuals receiving HAART, a total of 14% of regimens were switched, the majority occurring after 6 months of therapy.

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