1 results match your criteria: "Charlie Norwood VA Hospital and Medical Center[Affiliation]"
Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancer.
Semin Cancer Biol
October 2016
Department of Medicine, Georgia Cancer Center and Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Biochemistry and Molecular Biology, Georgia Cancer Center and Medical College of Georgia, Augusta University, Augusta, GA 30912, USA; Research Service, Charlie Norwood VA Hospital and Medical Center, Augusta, GA 30912, USA. Electronic address:
Article Synopsis
- Prostate cancer (PCa) is the most common cancer in men, driven by hormones, and while advances in treatment have improved survival, over 20% of patients may develop aggressive forms that resist current therapies.
- Research into natural products from marine sponges, mushrooms, and edible plants is ongoing, as these compounds may target multiple mechanisms of cancer progression, unlike many synthetic drugs that often focus on a single target.
- Nutraceuticals that modulate androgen receptor signaling and other pathways show promise as potential treatments for hormone-refractory PCa, possibly serving as either standalone therapies or in conjunction with traditional treatments.