4 results match your criteria: "Charite-Universitätsmedizin[Affiliation]"

Soft tissue sarcomas (STSs) are a diverse group of rare malignant soft tissue tumors with a high disease burden. Treatment protocols are complex and, to this day, a precise recommendation for the surgical margin width is lacking. The present study aims to analyze the width of the surgical margins in STS resection specimens and analyze them for local and systemic disease-free survival as well as for most frequent histologic STS subtypes.

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Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage.

Hypertension

August 2019

From the Charité-Universitätsmedizin Berlin, corporate member of Freie Universitaät Berlin, Humboldt-Universitaät zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany (N.B., A.F.-L., S.B., J.G., Arne Thiele, U.K.).

Article Synopsis
  • - The study investigates how subendocardial damage due to hypertension impacts the structure and function of the heart, highlighting early signs of cardiac problems even in asymptomatic individuals.
  • - Mice induced with subendocardial scarring showed diastolic dysfunction, changes in myocardial deformation, and increased expression of specific biomarkers, while systolic function remained normal.
  • - Advanced imaging techniques indicated that alterations in myocardial microstructure, particularly in subepicardial myofibers, can serve as early indicators for subendocardial fibrosis, with high sensitivity and specificity for predicting cardiac damage.
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Article Synopsis
  • A study analyzed dietary patterns across nine European countries to see how they relate to asthma and allergic symptoms, using a food frequency questionnaire and respiratory symptom assessments from over 3,200 participants aged 15-77.
  • Two main dietary patterns were identified: one high in animal proteins and carbohydrates, and the other rich in fruits and vegetables.
  • The results indicated that the diet high in animal proteins and carbohydrates was linked to worse asthma outcomes, including higher asthma scores, greater prevalence of current asthma, wheezing, atopic status, and reduced lung function.
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