4 results match your criteria: "Charite--Universitätsmedizin Berlin[Affiliation]"
Surgical Margins in Soft Tissue Sarcoma Management and Corresponding Local and Systemic Recurrence Rates: A Retrospective Study Covering 11 Years and 169 Patients in a Single Institution.
Life (Basel)
October 2022
Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13351 Berlin, Germany.
Article Synopsis
- Soft tissue sarcomas (STSs) are rare malignant tumors with complex treatment protocols and no definitive guidelines on surgical margin width.
- The study analyzed 169 patients with localized STSs of the extremities or trunk, focusing on the impact of surgical margin width on local and systemic disease-free survival.
- Results indicated that low-grade STSs show better local control with margins of at least 2 mm, while high-grade STSs benefit from intact muscle fascia at the margin, although surgical margin width appears less critical when combined with adjunct radiochemotherapy.
Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage.
Hypertension
August 2019
From the Charité-Universitätsmedizin Berlin, corporate member of Freie Universitaät Berlin, Humboldt-Universitaät zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Berlin, Germany (N.B., A.F.-L., S.B., J.G., Arne Thiele, U.K.).
Article Synopsis
- - The study investigates how subendocardial damage due to hypertension impacts the structure and function of the heart, highlighting early signs of cardiac problems even in asymptomatic individuals.
- - Mice induced with subendocardial scarring showed diastolic dysfunction, changes in myocardial deformation, and increased expression of specific biomarkers, while systolic function remained normal.
- - Advanced imaging techniques indicated that alterations in myocardial microstructure, particularly in subepicardial myofibers, can serve as early indicators for subendocardial fibrosis, with high sensitivity and specificity for predicting cardiac damage.
Dupilumab in Treatment of Chronic Prurigo: A Case Series and Literature Review.
Acta Derm Venereol
September 2019
Department of Dermatology, Venereology and Allergology, Charité - Universitäätsmedizin Berlin, Berlin, Germany.
Dietary patterns and respiratory health in adults from nine European countries-Evidence from the GA LEN study.
Clin Exp Allergy
November 2018
Population Health and Occupational Medicine, National Heart and Lung Institute, Imperial College London, London, UK.
Article Synopsis
- A study analyzed dietary patterns across nine European countries to see how they relate to asthma and allergic symptoms, using a food frequency questionnaire and respiratory symptom assessments from over 3,200 participants aged 15-77.
- Two main dietary patterns were identified: one high in animal proteins and carbohydrates, and the other rich in fruits and vegetables.
- The results indicated that the diet high in animal proteins and carbohydrates was linked to worse asthma outcomes, including higher asthma scores, greater prevalence of current asthma, wheezing, atopic status, and reduced lung function.