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Morphologic spectrum of estrogen receptor-negative breast carcinoma.

Arch Pathol Lab Med

March 2002

Department of Histopathology, Charing Cross Hospital and Imperial College of Science, Technology and Medicine, London, United Kingdom.

Context: Estrogen receptor (ER)-negative breast carcinomas are a heterogeneous group of breast cancers that are generally thought to be aggressive.

Objective: To determine the morphologic and immunohistochemical spectrum of a consecutive series of ER-negative breast carcinomas, in an attempt to understand the pathogenesis and behavior of these lesions.

Design: Seventy-four consecutive cases of ER-negative invasive carcinomas were studied.

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