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[Effects of chronic mercury poisoning on blood coagulation and fibrinolysis systems].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi

December 2005

Center of Occupational Disease and Poisoning Treatment, Chaoyang Hospital Affiliated to Capitol Medical University, Beijing 100020, China.

Objective: To investigate the effects of chronic mercury poisoning on blood coagulation and fibrinolysis systems, and the possible mechanism.

Methods: Twenty-seven patients with chronic mercury poisoning were studied with 30 healthy people as control. Thrombomodulin (TM), tissue plasminogen activator (t-PA), plasminogen activator inhibitor (PAI), interleukin-13 (IL-13), interleukin-18 (IL-18), soluble intercellular adhesion molecule-1 (SICAM-1) were examined with ELISA methods, and superoxide dismutase (SOD) and lipid peroxidation (LPO) was examined with chemical catalysis methods.

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