3,306 results match your criteria: "Changzhou University.[Affiliation]"

In this study, CO reacted with a curing agent through nucleophilic addition to form ammonium salts, enabling the stable capture and internal release of CO, which achieved gas-phase nucleation and foaming. Additionally, the introduction of wave-absorbing agents improved the absorption mechanism and promoted uniform foaming. This nucleation-free foaming process relies on the induced growth of gas nuclei and the synergistic effect of the wave-absorbing agents, effectively preventing the uneven foaming issues caused by traditional nucleating agents.

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Amide-amine (PAMAM) dendrimers are biodegradable, non-immunogenic, genotoxic, and biocompatibible, which make them excellent materials for biological applications. In order to reduce the cytotoxicity of the designed branched molecules, a four-armed branched nucleus (B4) of PAMAM dendrimers as hyperbranched molecules was fused with polyhexamethylene biguanide (PHMB) (A2); hyperbranched polymeric biguanides (PAPBs) with a four-arm central core PAMAM structure were synthesized. The bactericidal and cell toxicity tests showed that PAPB had excellent bactericidal activity against both Gram-positive bacteria and Gram-negative, and the chemical binding of PHMB and PAMAM had synergistic effects.

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Hardness-Dependent Freshwater Quality Criteria for the Protection of Aquatic Organisms for Cadmium in China.

Toxics

December 2024

State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.

Cadmium poses a significant threat to freshwater aquatic organisms and ecosystems, making it essential to establish regional freshwater quality criteria (FWQC) in China to safeguard these organisms. The toxicity database for cadmium covered 249 acute toxicity data from 52 species (seven phyla and 27 families) and 62 chronic toxicity data from 21 species (four phyla and 12 families). During short-term exposure, displayed the most sensitivity to cadmium, whereas showed the most sensitivity in long-term exposure scenarios.

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The Application of Machine Learning on Antibody Discovery and Optimization.

Molecules

December 2024

School of Pharmacy & School of Biological and Food Engineering, Changzhou University, Changzhou 213164, China.

Antibodies play critical roles in modern medicine, serving as diagnostics and therapeutics for various diseases due to their ability to specifically bind to target antigens. Traditional antibody discovery and optimization methods are time-consuming and resource-intensive, though they have successfully generated antibodies for diagnosing and treating diseases. The advancements in protein data, computational hardware, and machine learning (ML) models have the opportunity to disrupt antibody discovery and optimization research.

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LncSL: A Novel Stacked Ensemble Computing Tool for Subcellular Localization of lncRNA by Amino Acid-Enhanced Features and Two-Stage Automated Selection Strategy.

Int J Mol Sci

December 2024

School of Computer Science and Artificial Intelligence Aliyun School of Big Data School of Software, Changzhou University, Changzhou 213164, China.

Long non-coding RNA (lncRNA) is a non-coding RNA longer than 200 nucleotides, crucial for functions like cell cycle regulation and gene transcription. Accurate localization prediction from sequence information is vital for understanding lncRNA's biological roles. Computational methods offer an effective alternative to traditional experimental methods for annotating lncRNA subcellular positions.

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(1) Background: As digital technology continues to reshape visual landscapes, understanding how design elements influence customer experience has become essential. Eye-tracking technology offers a powerful, quantitative approach to assessing visibility, aesthetics, and design components, providing unique insights into visual engagement. (2) Methods: This paper presents a systematic review of eye-tracking methodologies applied in design research.

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Long-term exposure to Emamectin benzoate impairs reproductive health in adult zebrafish and alters neurodevelopment in their offspring.

J Hazard Mater

December 2024

Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment, Nanjing 210042, China. Electronic address:

Emamectin benzoate (EMB) is a widely used insecticide that can accumulate in aquatic environments under specific conditions of high application intensity or improper management, posing potential risks to aquatic organisms and human health. This study aimed to evaluate the reproductive toxicity of long-term EMB exposure in zebrafish (Danio rerio) and neurodevelopmental toxicity in their offspring. Zebrafish embryos were exposed to various concentrations of EMB (0, 0.

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Enhancing Optical Properties of Lead-Free CsNaBiCl Nanocrystals via Indium Alloying.

Inorg Chem

January 2025

School of Materials Science and Engineering, Jiangsu Engineering Laboratory of Light-Electricity-Heat Energy-Converting Materials and Applications, Changzhou University, Changzhou 213164, PR China.

This study presents the synthesis and characterization of CsNaBiCl nanocrystals (NCs) doped with varying concentrations of In to improve their luminescent properties. Utilizing a colloidal solution method, we systematically varied the In concentration to identify the optimal alloying level for enhancing the photoluminescence (PL) properties of the CsNaBiCl NCs. Structural analysis confirmed that the In-alloyed NCs maintained high crystallinity and a uniform cubic shape.

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Advances in the Study for Modulators of Transient Receptor Potential Vanilloid (TRPV) Channel Family.

Curr Top Med Chem

January 2025

School of Pharmacy & School of Biological and Food Engineering, Changzhou University, Changzhou, 213164, Jiangsu, PR China.

Article Synopsis
  • TRPV channels are part of a larger superfamily and are found in many cell types, with TRPV1-4 being sensitive to temperature and TRPV5-6 being selective for calcium ions.
  • These channels are important in various physiological processes and can be influenced by internal and external compounds, making them a target for pharmacological research.
  • Modulating these channels is crucial because it could lead to treatments for diseases like neurodegenerative disorders, pain, cancer, and skin issues, and there has been recent progress in exploring their ligands and related pharmacological effects.
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Ordered Photoexfoliation for Polypseudorotaxane Nanosheets.

ACS Macro Lett

January 2025

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200438, China.

Two-dimensional layered structural materials exhibit a wide range of properties due to their ultrahigh specific surface area. However, achieving ordered exfoliation to obtain uniform two-dimensional structures remains challenging. In this study, we developed a supramolecular system by covalently bonding hexathiobenzene (HB) into β-cyclodextrin to create a light-responsive moiety, followed by coassembly with bipyridine and nickel ions to form a polypseudorotaxane (PR) system, which enables an light-induced exfoliation strategy for two-dimensional materials.

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Low-temperature direct ammonia fuel cell (DAFC) stands out as a more secure technology than the hydrogen fuel cell system, while there is still a lack of elegant bottom-up synthesis procedures for efficient ammonia oxidation reaction (AOR) electrocatalysts. The widely accepted d-band center, even with consideration of the d-band width, usually fails to describe variations in AOR reactivity in many practical conditions, and a more accurate activity descriptor is necessary for a less empirical synthesis path. Herein, the upper d-band edge, ε, derived from the d-band model, is identified as an effective descriptor for accurately establishing the descriptor-activity relationship.

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Typical biosensing platforms are based on the "lock-and-key" approach, providing high specificity and sensitivity for environmental and food safety monitoring. However, they are limited in their ability to detect multiple analytes simultaneously. With the use of pattern identification methods, biosensor arrays can detect faint fluctuations caused by multiple analytes with similar properties in complex systems.

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High-capacity power battery can be attained through the elevation of the cut-off voltage for LiNiCoMnO high-nickel material. Nevertheless, unstable lattice oxygen would be released during the lithium deep extraction. To solve the above issues, the electronic structure is reconstructed by substituting Li ions with Y ions.

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Dichloroacetic acid (DCAA), trichloroacetic acid (TCAA), and bromate (BrO) are disinfection byproducts (DBPs) formed during drinking water treatment and pose health risks. Rapid and reliable detection of these DBPs is essential for ensuring water safety. Non-suppressed ion chromatography (IC)-electrospray ionization mass spectrometry (IC-ESI-MS/MS) offers a promising approach for simultaneous analysis of organic haloacetic acids (HAAs) and inorganic oxyhalides, but previous methods using toxic methylamine can pose health risks.

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The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.

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The high-temperature mechanical properties and fracture mechanism of selective laser melting (SLM) manufactured nickel-based alloy are highly important for its application. In this article, small punch test (SPT) method is used to study the mechanical properties of SLM-manufactured GH4169 over a wide temperature range from 25°C to 600°C. With the increase of temperature, the decreasing ratio of maximum load is only 18.

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Magnetic Janus SiO nanoparticles immobilized protease mutant T70I as a novel clarification agent for juice processing.

Int J Biol Macromol

December 2024

Jiangsu Key Laboratory of Sericultural and Animal Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212100, PR China; Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agricultural and Rural Affairs, The Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, Jiangsu 212100, PR China; Jiangsu Key Laboratory of Clean Energy Storage and Conversion, Jiangsu University of Technology, Changzhou, Jiangsu 213001, PR China. Electronic address:

The juice processing industry offers several benefits, including promoting health and wellness through the delivery of beverages rich in nutrients. Nonetheless, the industry encounters significant challenges regarding new technologies for processing and preservation given that they can be costly and labor-intensive. In this study, magnetic Janus silica (SiO) nanoparticle which offers multifunctionality and high stability was synthesized and subsequently immobilized with a protease mutant T70I (T70I@MSNs) to serve as a clarifying agent in juice.

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Low-Cost Intrinsic Flame-Retardant Bio-Based High Performance Polyurethane and its Application in Triboelectric Nanogenerators.

Adv Sci (Weinh)

December 2024

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Institute of Functional Materials, Research Base of Textile Materials for Flexible Electronics and Biomedical Applications (China Textile Engineering Society), Shanghai Key Laboratory of Lightweight Composite, Shanghai Engineering Research Center of Nano Biomaterials and Regenerative Medicine, Donghua University, Shanghai, 201620, P. R. China.

Flammability is a significant challenge in polymer-based electronics. In this regard, triboelectric nanogenerators (TENGs) have enabled a safe means for harvesting mechanical energy for conversion into electrical energy. However, most existing polymers used for TENGs are sourced from petroleum-based raw materials and are highly flammable, which can further accelerate the spread of fire and harm the ecological environment.

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Numerical simulation study on the influence of bend diameter rate on the flow characteristics of nature gas hydrate particles.

Sci Rep

December 2024

Jiangsu Key Laboratory of Oil-Gas Storage and Transportation Technology, Changzhou University, Changzhou, 213164, Jiangsu, China.

Bend pipe is a common part of long distance pipeline. There is very important to study the flow law of hydrate particles in the bend pipe, and pipeline design will be optimized. In addition, the efficiency and safety of pipeline gas transmission will be improved.

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A stimuli-responsive drug delivery system based on konjac glucomannan, carboxymethyl chitosan and mesoporous polydopamine nanoparticles.

Int J Biol Macromol

December 2024

Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. Electronic address:

A stimuli-responsive drug delivery system is developed for controlled delivery of curcumin (Cur) and chemo-photothermal therapy of breast cancer (BC). Cur is first loaded into mesoporous polydopamine nanoparticles (mPDA NPs) by π-π stacking, and then the Cur loaded mPDA NPs (mPDA NPs@Cur) are encapsulated in the hydrogels prepared through the crosslinking of oxidized konjac glucomannan (oxKGM) and carboxymethyl chitosan (CMCS). Owing to the pH-sensitivity of the hydrogels and the outstanding photothermal conversion capability of mPDA NPs, the release of Cur from the hydrogels can be greatly accelerated in acidic media upon near infrared (NIR) irradiation.

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Enhanced oxidative potential and SO heterogeneous oxidation on candle soot after photochemical aging: Influencing mechanisms of different irradiation wavelengths.

Environ Pollut

December 2024

School of Environmental Science and Engineering, Changzhou University, Changzhou, 213164, China; Key Laboratory of Advanced Plasma Catalysis Engineering for China Petrochemical Industry, Jiangsu, 213164, China. Electronic address:

Photochemistry plays a significant role in the atmospheric aging processes of soot. However, the physicochemical properties and changes in environmental and health effects of soot particles from sacrificial sources after photochemical aging remain unclear. The reaction mechanisms of soot under different irradiation wavelengths require further investigation.

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This comprehensive study focused on evaluating and selecting seven distinct commercial membranes to develop BTESE/PA membranes. This method effectively facilitated the extraction of cynaroside from the complex composition of peony seed meal. We subsequently conducted a thorough investigation into its biological properties.

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Poor selectivity to tumor cells is a major drawback in the clinical application of the antitumor drug docetaxel (DTX). Peptide-drug conjugates (PDCs) constructed by modifying antitumor drugs with peptide ligands that have high affinity to certain overexpressed receptors in tumor cells are increasingly assessed for their possibility of tumor-selective drug delivery. In the present research, DTX is condensed with 3-(pyridin-2-yldisulfanyl) propanoic acid via ester bond to obtain the intermediate Py-SS-DTX.

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[Mechanisms of Rhizosphere Microorganisms in Regulating Plant Root System Architecture in Acidic Soils].

Huan Jing Ke Xue

January 2025

State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.

Red soil occupies an important position in China's agriculturally cultivated land resources. However, its low pH value, high aluminum concentration, and inefficient phosphorus utilization limit the productivity of acidic red soil farmland. Plant roots exhibit remarkable plasticity, capable of absorbing water and nutrients and modulating root system architecture in response to biotic and abiotic stresses, either autonomously or through rhizosphere microorganisms.

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Identification of the pollution source of surface water in a chemical park was difficult because many industrial enterprises with complex wastewater components and similar characteristics are located there. Therefore, a national-level chemical park in Jiaxing City was studied, and wastewater samples from ten batches of seven key enterprises in the park were collected and analyzed using 3D excitation emission matrix spectrometry (EEMS) and gas chromatography-mass spectrometry (GC-MS). Parallel factor analysis was used to extract common components of EEMS spectra from different batches of drainage in the same enterprise to construct an EEMS characteristic data matrix.

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