1 results match your criteria: "Changzhou Municipal Second People's Hospital Affiliated to Nanjing Medical University[Affiliation]"
[Coexisting Mutations in IDH1/2-Mutated Acute Myeloid Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
October 2019
Department of Hematology, Changzhou Municipal Second People's Hospital Affiliated to Nanjing Medical University, Changzhou 213003, Jiangsu Province, China.
Objective: To explore the coexisting mutations in IDH-mutated acute myeloid leukemia(AML) and its relation with partial clinical parametrs.
Methods: The exon 4 mutation of IDH1/2 gene was screened by using genome DNA-PCR combined with sanger sequencing, 51 targeted gene mutations in the patients with IDH1/2 mutation were detected by using high throughput DNA sequencing combined with sanger sequencing.
Results: Among 358 patients, the IDH1/2 mutation was found in 46 cases including IDH1 mutation in 35 cases and IDH2 mutation in 11 cases, 97.