10,072 results match your criteria: "Changhai Hospital.[Affiliation]"
Lancet Neurol
January 2025
Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Cancer Lett
December 2024
Department of Gastrointestinal Surgery I Section, Renmin Hospital of Wuhan University, Wuhan, 430060, China. Electronic address:
Gastric cancer is a common global malignancy that requires detailed study of its development mechanisms. Although LncRNA FIRRE is known to play a crucial role in the progression and treatment resistance of several cancers, its effect on gastric cancer is not well understood. This study confirms the impact of FIRRE on the malignant behavior of gastric cancer.
View Article and Find Full Text PDFTech Coloproctol
December 2024
Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
Objective: To investigate the optimal interval between self-expanding metal stent (SEMS) placement and radical surgery in patients with obstructive colorectal cancer.
Method: In this study, a retrospective research design was used to select 125 patients with obstructive colorectal cancer who underwent colonoscopic SEMS placement with subsequent radical surgery between February 2011 and November 2022 at Shanghai Changhai Hospital. In addition, their clinical data and therapeutic efficacy were examined.
Int J Mol Med
February 2025
Department of Dermatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.
Following the publication of the above article, the authors contacted the Editorial Office to explain that three pairs of the western blots featured in Fig. 4 on p. 165 had inadvertently been duplicated in this figure.
View Article and Find Full Text PDFEur Radiol
December 2024
Department of Neurology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Background: Intracranial atherosclerosis (ICAS) is the leading cause of ischemic stroke in Asians and the recurrent rate remains high despite the optimal medical treatment. This study aimed to confirm that follow-up high-resolution magnetic resonance imaging (hrMRI) provided essential values in predicting subsequent cerebral ischemic events in patients with ICAS.
Methods: Patients with moderate to severe stenosis in the middle cerebral artery (MCA) defined by magnetic resonance (MRA) or computed tomography angiography (CTA) were recruited from three centers retrospectively.
J Cardiothorac Surg
December 2024
Department of Vascular Surgery, Changhai Hospital, Second (Navy) Military Medical University, Shanghai, 200433, China.
Background: Ruptured abdominal aortic aneurysm (RAAA) is a fatal disease. This study aimed to assess the prognostic value of the preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with RAAA undergoing endovascular aneurysm repair (EVAR).
Materials And Methods: This retrospective study included patients with RAAA who underwent EVAR from 2012 to 2022.
Colloids Surf B Biointerfaces
December 2024
Department of Chemistry, University of Shanghai for Science and Technology, No. 516 Jungong Road, Shanghai 200093, China. Electronic address:
Cochrane Database Syst Rev
December 2024
Paediatrics, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden, Lund, Sweden.
Background: Preterm and low birth weight infants are at an early stage of development, and do not receive adequate maternal circadian signals. They are often cared for over prolonged periods of hospitalisation in neonatal intensive care units (NICU), where environmental circadian stimuli are lacking. Exposure to artificial light-dark cycles may stimulate the development of the circadian system and improve clinical outcomes.
View Article and Find Full Text PDFBMC Med Imaging
December 2024
Department of Radiology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, 361000, People's Republic of China.
Purpose: Exploring the computed tomography (CT), magnetic resonance imaging (MRI), and fluorodeoxyglucose positron emission tomography (FDG-PET)/CT Multimodal Imaging Characteristics of Desmoplastic Small Round Cell Tumor (DSRCT) to enhance the diagnostic proficiency of this condition.
Methods: A retrospective analysis was performed on clinical data and multimodal imaging manifestations (CT, MRI, FDG-PET/CT) of eight cases of DSRCT. These findings were systematically compared with pathological results to succinctly summarize imaging features and elucidate their associations with both clinical and pathological characteristics.
Background: Prolonged postoperative ileus (PPOI) reportedly leads to compromised postoperative recovery and increased healthcare costs. However, the evidence for this claim was obtained from studies that included patients with both primary and secondary PPOI. How primary PPOI affects the hospital length of stay (LOS) and healthcare costs is not well documented.
View Article and Find Full Text PDFCell Death Discov
December 2024
Department of Clinical Pharmacy, Sanming First Hospital, Affiliated Hospital of Fujian Medical University, Sanming City, Fujian Province, China.
Among the common malignancies, colorectal cancer (CRC) is often resistant to chemotherapy because of drug resistance and severe toxicity. Currently, aspirin is one of the most promising CRC chemopreventive drugs, both for primary prevention and for reducing the chance of recurrence and metastasis following radical surgery in patients with early-stage CRC. Oleanolic acid is a potential antineoplastic drug that has an antagonistic effect on many kinds of tumors.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2024
Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Naval Medical University (Changhai Hospital), Shanghai200433, China.
To explore the efficacy of ansa cervicalis anterior root-recurrent laryngeal nerve (RLN) anastomosis in the treatment of unilateral vocal fold paralysis (UVFP) and to analyze the effect of different pathogenic factors on efficacy. From January 2010 to January 2022, 428 patients (187 males and 241 females) at Changhai Hospital with UVFP who underwent ansa cervicalis anterior root-RLN anastomosis due to thyroid surgery, thoracic surgery, idiopathic vocal ford paralysis or high cranial base injury were analyzed. The course of nerve injury ranged from 6 to 24 months.
View Article and Find Full Text PDFWorld Neurosurg
January 2025
Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, Harbin, China. Electronic address:
Background: There are still some patients with acute anterior circulation large vessel occlusion stroke experienced unsuccessful recanalization after endovascular thrombectomy (EVT). The efficacy of intravenous alteplase before thrombectomy for such patients is unknown. We performed this study to investigate whether prior intravenous alteplase could affect the outcome of patients with unsuccessful recanalization.
View Article and Find Full Text PDFCerebrovasc Dis
December 2024
Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Introduction: There remains a lack of consensus among physicians regarding the blood pressure (BP) management strategy for acute ischemic stroke patients; this study sought to determine current practice patterns and extension of consensus among stroke physicians after publications of several randomized controlled trials (RCTs).
Methods: An online survey of stroke clinicians registered to the Oriental Conference of Interventional Neurovascology (OCIN) platform and Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2/MT) trail collaborators was conducted to investigate the BP management strategy after mechanical thrombectomy (MT). The survey was sent out in March 2024, extracted within 1 month, and then analyzed comprehensively using descriptive statistics.
Mol Biomed
December 2024
Department of Hepatopanreatobiliary Surgery, Changhai Hospital, 168 Changhai Road, Yangpu District, Shanghai, 200433, China.
Cancer, characterized by its immune evasion, active metabolism, and heightened proliferation, comprises both stroma and cells. Although the research has always focused on parenchymal cells, the non-parenchymal components must not be overlooked. Targeting cancer parenchymal cells has proven to be a formidable challenge, yielding limited success on a broad scale.
View Article and Find Full Text PDFSmall
December 2024
Materials Genome Institute, Shanghai Engineering Research Center for Integrated Circuits and Advanced Display Materials, and Shanghai Engineering Research Center of Organ Repair, Shanghai University, Shanghai, 200444, China.
Nanozymes with multienzyme-like activity have sparked significant interest in anti-tumor therapy via responding to the tumor microenvironment (TME). However, the consequent induction of protective autophagy substantially compromises the therapeutic efficacy. Here, a targeted nanozyme system (Fe-Arg-CDs@ZIF-8/HAD, FZH) is shown, which enhances synergistic anti-tumor ferroptosis/apoptosis therapy by leveraging machine learning (ML).
View Article and Find Full Text PDFAm J Transl Res
November 2024
Department of Emergency, Changhai Hospital Affiliated to Naval Medical University Shanghai 200433, The People's Republic of China.
is an obligate aerobic, Gram-negative bacillus belonging to the family of Weeksellacease. In recent years, there has been a gradual increase in related infections, especially in chronically hospitalized, immunocompromised populations that often develop severe pneumonia. Severe pneumonia is one of the common critical illnesses.
View Article and Find Full Text PDFPeerJ
December 2024
Department of Anesthesiology and Surgical Intensive Care Unit, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Context: AMD3100, a CXCR4 antagonist, has beneficial effects immaculate in the treatment of acute lung injury (ALI).
Objective: ALI is a severe inflammatory condition associated with poor prognosis and limited treatment options. AMD3100, has therapeutic effects that reduce ALI.
Ann Surg
December 2024
Department of General Surgery, Shanghai Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Objective: To develop and validate a signature to precisely predict prognosis in pancreatic ductal adenocarcinoma (PDAC) undergoing resection and adjuvant chemotherapy.
Summary Background Data: PDAC is largely heterogeneous, and responds discrepantly to treatment.
Methods: 551 consecutive patients with PDAC from 3 tertiary centers were initially enrolled.
Ther Adv Respir Dis
December 2024
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Naval Medical University (Shanghai Changhai Hospital), No. 168 Changhai Road, Yangpu District, Shanghai, China.
Background: Differences between virtual bronchoscopic navigation (VBN) systems and their impacts on the diagnostic yield of transbronchial biopsy (TBB) of peripheral pulmonary nodules (PPNs) remain unclear.
Objectives: To compare the Synapse 3D system (Version 4.4, Fujifilm, Japan) and DirectPath system (Version 2.
Mil Med Res
December 2024
Department of Urology, University College Hospital of London, London, NW1 2BU, UK.
J Adv Res
December 2024
Changhai Clinical Research Unit, Changhai Hospital of Naval Medical University, Shanghai, China. Electronic address:
AJNR Am J Neuroradiol
December 2024
Department of Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Background And Purpose: Lateral sinus dural arteriovenous fistulas (LS-DAVFs) carry a higher rate of recurrence after endovascular treatment (EVT). Our objective was to investigate the independent predictors of recurrence and unfavorable functional outcome of low-and intermediate-grade LS-DAVFs after EVT.
Materials And Methods: Retrospectively reviewed our database of prospectively collected information for all patients with low and intermediate-grade LS-DAVFs that underwent EVT from May 2004 to December 2021.
Cancer Cell
January 2025
State Key Laboratory of Medicinal Chemical Biology, Institute of Immunology, College of Life Sciences, Nankai University, Tianjin 300071, China; Department of Immunology, Center for Immunotherapy, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China. Electronic address:
Deciphering mechanisms for cancer immune escape may provide targets for improving immunotherapy efficacy. By in vivo genome-wide CRISPR loss-of-function screening in a mouse model of triple negative breast cancer (TNBC), we uncovered a non-classical function of Cd28 in cancer cells to promote immune escape. Knocking out Cd28 in cancer cells increased infiltration of type I conventional DC (cDC1) and activated tumor-specific CD8 T cells, and pharmaceutical inducible knockdown of Cd28 inhibited pre-established tumor growth and overcame anti-PD-1 resistance in vivo.
View Article and Find Full Text PDFEcotoxicol Environ Saf
December 2024
School of Environmental and Biological Engineering, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China. Electronic address:
The increasing use of plastic food containers, particularly for pre-cooked meals and takeout services, has raised concerns regarding the potential health risks associated with plastic leachates. This study investigated the impact of leachates from heat-treated polypropylene (PP) plastic food containers on glucose and lipid metabolism using both in vitro and in vivo models. AML12 hepatocytes exposed to leachates from three different PP plastic containers exhibited significant disruptions in the homeostasis of lipid and glucose metabolism, evidenced by increased intracellular lipid content and altered gene expression related to lipogenesis, lipid uptake, lipolysis, and fatty acid β-oxidation.
View Article and Find Full Text PDF