Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet-Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity.

Dentin hypersensitivity (DH), marked by exposed dentinal tubules, presents as a sharp toothache triggered by stimuli and subsides when the stimuli are removed. To address the limitations of current commercial desensitizers in terms of acid resistance, friction resistance, and stability, a black phosphorus nanosheet-composited methacrylate gelatin hydrogel (GelMA/BP) is developed for DH treatment, leveraging the synergistic effects of photothermal therapy and biomineralization. Incorporating the BP nanosheet provided GelMA/BP with a stable photothermal response and the continuous release of phosphate anions, which blocked dentinal tubules by converting light energy into heat and initiating biomineralization.

Ultrasound-Controllable Release of Carbon Monoxide in Multifunctional Polymer Coating for Synergetic Treatment of Catheter-Related Infections.

Medical catheters are susceptible to biological contamination and pathogen invasion, leading to infection and inflammatory complications. The development of antimicrobial coatings for medical devices has emerged as a promising strategy. However, limited biological functionality and the incompatibility between bactericidal properties and biosafety remain great challenges.

Succinate Nanomaterials Boost Tumor Immunotherapy via Activating Cell Pyroptosis and Enhancing MHC-I Expression.

Despite the promising clinical applications of immunotherapy, its effectiveness is often limited by low immune responses and tumor immune escape. In this study, we introduce a simple and drug-free inorganic nanomaterial, sodium succinate (CHNaO NPs), prepared using a rapid microemulsion method to enhance cancer immunotherapy. The synthesized CHNaO NPs can release high concentrations of Na and succinate ions into tumor cells, leading to an increase in intracellular osmolarity.

Designing Ru-B-Cr Moieties to Activate the Ru Site for Acidic Water Electrolysis under Industrial-Level Current Density.

Developing highly efficient non-iridium-based active sites for acidic water splitting is still a huge challenge. Herein, unique Ru-B-Cr moieties have been constructed in RuO nanofibers (NFs) to activate Ru sites for water electrolysis, which overcomes the bottleneck of RuO-based catalysts usually possessing low activity for the hydrogen evolution reaction (HER) and poor stability for the oxygen evolution reaction (OER). The fabricated Cr, B-doped RuO NFs exhibit low overpotentials of 205 and 379 mV for acidic HER and OER at 1 A cm with outstanding stability lasting 1000 and 188 h, respectively.

A subcellular selective APEX2-based proximity labeling used for identifying mitochondrial G-quadruplex DNA binding proteins.

G-quadruplexes (G4s), as an important type of non-canonical nucleic acid structure, have received much attention because of their regulations of various biological processes in cells. Identifying G4s-protein interactions is essential for understanding G4s-related biology. However, current strategies for exploring G4 binding proteins (G4BPs) include pull-down assays in cell lysates or photoaffinity labeling, which are lack of sufficient spatial specificity at the subcellular level.

Matching P- and N-type Organic Electrochemical Transistor Performance Enables a Record High-gain Complementary Inverter.

The charge transport of channel materials in n-type organic electrochemical transistors (OECTs) is greatly limited by the adverse effects of electrochemical doping, posing a long-standing puzzle for the community. Herein, an n-type conjugated polymer with glycolated side chains (n-PT3) is introduced. This polymer can adapt to electrochemical doping and create more organized nanostructures, mitigating the adverse effects of electrochemical doping.

Bio-inspired anti-swelling amyloid-fiber lysozyme adhesive for rapid wound closure and hemostasis.

Instant adhesion to wet biological surfaces and reduced swelling of tissue adhesives are crucial for rapid wound closure and hemostasis. However, previous strategies to reduce swelling were always accompanied by a decrease in the tissue bonding strength of the adhesive. Moreover, the irreducibility of the covalent bonds in currently reported adhesives results in the adhesives losing their tissue adhesive ability.

Bifunctional Electrospun Nanocomposite Dressing: Integrating Antibacterial Efficacy and Controllable Antioxidant Properties for Expedited Wound Healing.

Current wound dressings are insufficient in simultaneously addressing bacterial infections and oxidative stress, which severely affects wound healing outcomes. To solve this problem, we introduced poly(ionic liquid) (PIL) with strong antibacterial properties and cerium oxide nanoparticles (CeONPs) with excellent antioxidant capabilities into polyacrylonitrile (PAN) nanofiber membranes to prepare a novel composite dressing. The PIL-CeONPs-PAN nanofiber membrane provides sustained antibacterial activity through stably embedded PIL, while the uniformly distributed CeONPs achieve controlled release, avoiding safety issues caused by the rapid release of active substances.

Atomically Dispersed Fe and Ni Sites for Efficient and Durable Oxygen Electrocatalysis.

Developing highly efficient, cost-effective, and robust electrocatalysts for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER) is paramount for the large-scale commercialization of renewable fuel cells and rechargeable metal-air batteries. Herein, a new ternary-atom catalyst that is composed of paired Fe sites and single Ni sites (as Fe-N and Ni-N) coordinated onto hollow nitrogen-doped carbon microspheres is developed. The as-synthesized catalyst exhibits remarkable activities toward both the ORR and OER in alkaline media, with superior performances to those of the control materials that contain only Fe-N or Ni-N sites.

Amylopectin-based Hydrogel Probes for Brain-machine Interfaces.

Implantable neural probes hold promise for acquiring brain data, modulating neural circuits, and treating various brain disorders. However, traditional implantable probes face significant challenges in practical applications, such as balancing sensitivity with biocompatibility and the difficulties of in situ neural information monitoring and neuromodulation. To address these challenges, this study developed an implantable hydrogel probe capable of recording neural signals, modulating neural circuits, and treating stroke.

Correction: Highly efficient yellow emission and abnormal thermal quenching in Mn-doped RbCdCl.

Correction for 'Highly efficient yellow emission and abnormal thermal quenching in Mn-doped RbCdCl' by Dayu Huang , , 2023, , 5715-5723, https://doi.org/10.1039/D3DT00453H.

Two-step spin transition around room temperature in a Fe complex.

Spin-crossover (SCO) at room temperature is a pivotal goal within the field of molecular magnetism. Herein, we attempt to assemble Fe SCO complexes using a substituted Hqsal ligand, HL (-(8-quinolyl)-2,3-dihydroxybenzaldimine). Two complexes [Fe(HL)]·X·2MeCN (X = BF for 1 and X = ClO for 2) were obtained and characterized.

Square planar Pd(II)/oximate complexes as 'metalloligands' for the directional assembly of 4f-metal ions: a new family of {LnPd} (Ln = lanthanide) clusters exhibiting slow magnetization relaxation.

A relatively unexplored approach in heterometallic chemistry of transition metals and lanthanides has been developed toward the controlled synthesis of a new family of linear heterotrinuclear Ln(III)-Pd(II)-Ln(III) complexes with the general formula [LnPd(pao)(NO)(MeOH)(HO)]·[Pd(pao)], where Ln = Dy (2), Gd (3), Er (4) and Yb (5). This strategy was based on the diamagnetic 'metalloligand' [Pd(pao)] (1), where pao is the anion of 2-pyridinealdoxime, containing two dangling oximate O-atoms which were to each other and available for binding with oxophilic lanthanide ions. Because of their -configuration, the [Pd(pao)] 'metalloligand' was able to direct the binding of two {Ln(NO)(MeOH)(HO)} units on opposite sites, thus yielding the reported trinuclear {Ln-Pd-Ln} clusters.

Why Does a Transition Metal Dichalcogenide Nanoribbon Narrow into a Nanowire under Electron Irradiation?

Transition metal dichalcogenide (TMDC) nanowires have practical applications in 1D electron channels, spintronics, optoelectronics, and catalysis due to their authentic subnanometer width (<1 nm) and intrinsic metallicity. Although narrowing of a TMDC nanoribbon into a nanowire under electron irradiation has been frequently observed in the synthesis of TMDC nanowires, the mechanism underlying this unexpected structural transformation remains a mystery. Here, to reveal the underlying mechanism, we combine first-principles calculations with a global structure search of 1D nanowires and show that a nanoribbon of 1H-phase MoS with a width narrower than 6 rings is energetically unfavorable compared with its nanowire counterpart due to the edge-edge interaction.

Regulating Electron Acceptor Unit to Construct Conjugated Polymer Probe for Raman Imaging of Tumor and Sentinel Lymph Nodes.

Donor-acceptor (D-A) conjugated polymers have large Stokes shifts, high photostability, and good biocompatibility and thus are ideal for use as Raman probes . However, few D-A conjugated polymers are used as Raman probes for Raman imaging due to their weak Raman signal intensity and intrinsic fluorescence interference. Here, we developed a D-A conjugated polymer probe (CDT-TT) containing alternating cyclopentadithiophene-thienothiophene units for Raman imaging of tumor and sentinel lymph nodes (SLNs).

Multi-resonance emitters with room-temperature phosphorescence in amorphous state and excited by visible light.

Unlike boron, nitrogen-containing multi-resonance emitters with thermally activated delayed fluorescence, here we report boron, sulfur (B, S)-based multi-resonance emitters with room-temperature phosphorescence (RTP) by inserting thiophene into a 5,9-dithia-13-boranaphtho[3,2,1-]anthracene skeleton that simultaneously realizes large singlet-triplet energy splitting and strong spin-orbital coupling, leading to efficient room-temperature phosphorescence in an amorphous state. Unlike most RTP emitters with ultraviolet excitation, the multi-resonance RTP emitters exhibit strong phosphorescence under daily-use blue/white LED lamps owing to their intense absorption in the visible-light region (400-486 nm). Meanwhile, such RTP behavior can be tuned by the number and fusing pattern of the thiophene moieties, with the emitters containing thiophene linked to boron atoms α-positions exhibiting bathochromatically shifted emissions and longer phosphorescence lifetimes (47.

Poly(Lactic Acid): Recent Stereochemical Advances and New Materials Engineering.

Poly(lactic acid) (PLA) is a representative biobased and biodegradable aliphatic polyester and a front-runner among sustainable materials. As a semicrystalline thermoplastic, PLA exhibits excellent mechanical and physical properties, attracting considerable attention in commodity and medical fields. Stereochemistry is a key factor affecting PLA's properties, and to this end, the engineering of PLA's microstructure for tailored material properties has been an active area of research over the decade.

Engineering Charge Transfer Characteristics in ZnO NRs/AgO NPs p-n Heterojunctions: Toward Highly Efficient and Recyclable Photocatalysts.

Staggered gap p-n heterojunction ZnO nanorods/AgO nanoparticles, a paradigm of photocatalysts, were developed via engineering the hydrothermal and coprecipitation method. Under simulated sunlight, the photocatalytic characteristics of ZnO/AgO(Zn/A) heterojunctions with varying mole ratios (from 8:1 to 8:4, named Zn/A-1-Zn/A-4) were systematically evaluated through the degradation of methylene blue (MB). The influence of key experimental variables, including photocatalyst concentration, MB concentration, and solution pH, on the photocatalyst performance was further analyzed.

Redox-Bipolar Covalent Organic Framework Cathode for Advanced Sodium-Organic Batteries.

Redox-active covalent organic frameworks (COFs) are promising candidates for sodium-ion batteries (SIBs). However, the construction of redox-bipolar COFs with the anions and cations co-storage feature for SIBs is rarely reported. Herein, redox-bipolar COF constructed from aniline-fused quinonoid units (TPAD-COF) is developed as the cathode material in SIBs for the first time.