High-Intensity Focus Ultrasound Ablation in Prostate Cancer: A Systematic Review.

Prostate cancer (PCa) outcomes vary significantly across risk groups. In early-stage localized PCa, the functional outcomes following radical prostatectomy (RP) can be severe, prompting increased interest in focal therapy, particularly High-Intensity Focused Ultrasound (HIFU). This study is to summarize the current clinical trials of HIFU on PCa.

Association of Sugar-Sweetened Beverages and Cardiovascular Diseases Mortality in a Large Young Cohort of Nearly 300,000 Adults (Age 20-39).

(1) Background: The association of sugar-sweetened beverages (SSBs) with cardiovascular disease (CVD) mortality in younger adults (age 20−39) is rarely mentioned in the literature. Younger adults are less vulnerable to CVDs, but they tend to consume more SSBs. This prospective study aimed to assess the association between CVD mortality and SSBs in younger adults between 1994 and 2017.

"Sugar-Sweetened Beverages" Is an Independent Risk From Pancreatic Cancer: Based on Half a Million Asian Cohort Followed for 25 Years.

Although the link between sugar-sweetened beverages (SSB) and pancreatic cancer has been suggested for its insulin-stimulating connection, most epidemiological studies showed inconclusive relationship. Whether the result was limited by sample size is explored. This prospective study followed 491,929 adults, consisting of 235,427 men and 256,502 women (mean age: 39.

A user-friendly objective prediction model in predicting colorectal cancer based on 234 044 Asian adults in a prospective cohort.

Background: Prediction models of colorectal cancer (CRC) had limited application for not being user-friendly. Whether fecal immunochemical tests (FITs) can help predict CRC has been overlooked.

Patients And Methods: With 1972 CRCs identified, 234 044 adults aged ≥40 years were successively enrolled between 1994 and 2008.

The effect of cholecystectomy on the risk of acute myocardial infarction in patients with gallbladder stones.

: To investigate the effect of cholecystectomy on the subsequent risk of acute myocardial infarction (AMI) in patients with gallbladder stones (GBS).: We used the Taiwan National Health Insurance Research Database (NHIRD) for hospitalization to conduct a retrospective nationwide population-based cohort study. The study cohort consisted of a total of 122,421 patients aged ≥20 years with cholecystectomy for GBS between 2000 and 2010.

The Risk of Venous Thromboembolism in Patients with Gallstones.

The objective of this study is to assess the relationship between gallstones and venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), and the risk of VTE after cholecystectomy for gallstones. This nationwide population-based cohort study retrieved the hospitalization database from the Longitudinal Health Insurance Research Database (LHID2000), a database belonging to the National Health Insurance (NHI) program of Taiwan. A total of 345,793 patients aged ≥ 18 years with gallstones diagnosed between 2000 and 2010 were identified as the study cohort.

Risk of head and neck cancer after chronic pancreatitis.

Background: To evaluate the relation of head and neck cancer to chronic pancreatitis by analyzing Taiwan's National Health Insurance Research Database.

Methods: We identified 11,237 patients with chronic pancreatitis as the case cohort, which was propensity score matched with another 11,237 patients without chronic pancreatitis by sex, age, index year, and comorbidities. We followed both cohorts between January 1, 2000, and December 31, 2011 to measure the incidence of head and neck cancer.

Association of Cholecystectomy with the Risk of Prostate Cancer in Patients with Gallstones.

Objectives: To assess the association of cholecystectomy with the risk of prostate cancer in patients with gallstones.

Methods: This nationwide population-based cohort study was conducted by retrieving the Longitudinal Health Insurance Research Database (LHID2000) for inpatient claims in the Taiwan National Health Insurance (NHI) program. The study cohort consisted of 72,606 men aged 20 years with gallstones undergoing cholecystectomy between 2000 and 2010.

The Effect of Cholecystectomy on the Risk of Colorectal Cancer in Patients with Gallbladder Stones.

Unlabelled: To evaluate the risk of colorectal cancer (CRC) after cholecystectomy for gallbladder stones (GBS).

Methods: This nationwide population-based cohort study analyzed the inpatient data from the Taiwan National Health Insurance Research Database. The study cohort comprised of 83,963 patients aged 20 years undergoing cholecystectomy for GBS between 2000 and 2010.

The risk of coronary heart disease after diagnosis of gallbladder polyp: a retrospective nationwide population-based cohort study.

Background: To assess the subsequent risk of coronary heart disease (CHD) after the diagnosis of gallbladder polyp (GP).

Methods: We identified 2,815 GP patients aged ≥20 years from the Longitudinal Health Insurance Database between 2000 and 2011 and followed up the patients until the occurrence of CHD or the end of 2011, the patient would be censored in the occurrence of death, missed information, or withdrawal from the NHI. We selected 11,260 non-GP subjects by 4:1 randomly matching with the case cohort according to age, sex, and index date of GP diagnosis.

Insulin enhances and metformin reduces risk of colorectal carcinoma in type-2 diabetes.

Background: Identifying colorectal cancer associated risks is important for conducting a program for the survey and prevention of colorectal cancer.

Aim: To investigate the association between use of insulin or metformin with colorectal cancer (CRC) in type 2 diabetes (T2DM).

Design: Population-based cohort study.

Association Between Type I and II Diabetes With Gallbladder Stone Disease.

To assess the association of type 1 diabetes (T1DM) and type 2 diabetes (T2DM) with the subsequent development of gallbladder stone disease (GSD). Cohort Study. We identified two study cohort groups to evaluate the association of T1DM and T2DM with the development of GSD.

Gallbladder Stone Disease Is Associated with an Increased Risk of Migraines.

Several pathophysiological mechanisms are shared in both gallbladder stone disease (GSD) and migraines. We assessed the migraine risk for patients diagnosed with GSD. We identified 20,427 patients who were diagnosed with GSD between 2000 and 2011 from Taiwan's National Health Insurance Research Database (NHIRD) as the study cohort.

Association between Hashimoto's thyroiditis and cholelithiasis: a retrospective cohort study in Taiwan.

Objective: To investigate the relation of Hashimoto's thyroiditis (HT) to cholelithiasis and cholecystectomy in a retrospective population-based study.

Setting: Cohort study.

Participants: We identified 1268 patients aged ≥20 years with HT between 2000 and 2010 as the study cohort.

A retrospective administrative database analysis of the association between clonorchiasis or helminthiasis and the development of cholelithiasis.

Purpose: Parasite infestation (PI) is reportedly related to intrahepatic stones (IHSs) and common bile duct (CBD) stones. This study assessed the association of clonorchiasis and helminthiasis with the sub-types of cholelithiasis.

Methods: The study cohort consisted of 713 patients who were aged ≥20 years with clonorchiasis or helminthiasis for the first time between 2000 and 2010 from the National Health Insurance Research Database.

Risk of gallstones in patients with obstructive sleep apnea: a nationwide observational cohort study.

Purpose: To assess the association between obstructive sleep apnea (OSA) and gallstones.

Methods: We identified 3827 patients aged ≥ 20 years with OSA between 2000 and 2010 from the Longitudinal Health Insurance Research Database 2000 (LHID2000) as the study cohort. The beneficiaries without OSA were randomly selected and propensity-matched with the study cohort in a 1:1 ratio according to age; sex; occupation; urbanization; comorbidities of hypothyroidism, hyperlipidemia, diabetes, liver cirrhosis, alcohol-related illness, hypertension, chronic obstructive pulmonary disease (COPD), obesity, inflammatory bowel disease, stroke, coronary artery disease (CAD), hepatitis B virus, and hepatitis C virus; and the index year.

Association between chronic pancreatitis and urolithiasis: A population-based cohort study.

Purpose: Chronic pancreatitis (CP) can cause fat or bile acid malabsorption due to exocrine insufficiency. Fat or bile acid malabsorption has been reported to increase the risk of urolithiasis through increased intestinal oxalate absorption. However, no studies have reported an association between CP and urolithiasis.