1 results match your criteria: "Chan Soon-Shiong Institute of Molecular Medicine at Windber (CSSIMMW)[Affiliation]"
Association of clinicopathologic and molecular factors with the occurrence of positive margins in breast cancer.
Breast Cancer Res Treat
February 2024
Chan Soon-Shiong Institute of Molecular Medicine at Windber (CSSIMMW), Windber, PA, USA.
Purpose: To explore the association of clinicopathologic and molecular factors with the occurrence of positive margins after first surgery in breast cancer.
Methods: The clinical and RNA-Seq data for 951 (75 positive and 876 negative margins) primary breast cancer patients from The Cancer Genome Atlas (TCGA) were used. The role of each clinicopathologic factor for margin prediction and also their impact on survival were evaluated using logistic regression, Fisher's exact test, and Cox proportional hazards regression models.