12,390 results match your criteria: "Cervical Spondylosis"

Purpose: Chronic cervical muscle injury is the first common cause of the development of cervical spondylosis, and Tuina can effectively promote the repair of chronic cervical muscle injury and alleviate neck pain, but the mechanism behind its efficacy is still unknown. The proliferation and differentiation of muscle satellite cells and the apoptosis of cervical myocytes play important roles in the repair of chronic cervical muscle injuries; therefore, this study aimed to explore the potential mechanisms of Tuina to promote the repair of cervical muscle injuries in terms of the proliferation and differentiation of satellite cells and the apoptosis of myocytes.

Patients And Methods: Twenty-eight Wistar rats were randomly divided into control group, model group, Tuina group, and meloxicam group, with 7 rats in each group.

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Article Synopsis
  • The study explores the effectiveness of a minimally invasive surgical technique, Mis-TLIF, combined with preoperative position reduction for treating lumbar isthmic spondylolisthesis, comparing it with traditional open surgery (Open-TLIF).
  • A total of 60 patients were analyzed over a six-year period, divided into an observation group receiving Mis-TLIF and a control group undergoing Open-TLIF, with both groups having similar demographics and disease characteristics.
  • The analysis focused on various surgical outcomes, including operation time, blood loss, hospital stay, radiation exposure, and complications, as well as patient recovery measured through pain and disability scales.
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BACKGROUND Lumbar fusion and internal fixation techniques have shown promise in treating lumbar disc herniation (LDH), yet the impact on lumbar function in young patients remains unclear. This study aimed to investigate the impact of lumbar fusion on lumbar function in young patients. MATERIAL AND METHODS A retrospective analysis was conducted on 330 patients diagnosed with LDH admitted to our hospital.

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Article Synopsis
  • Foraminal stenosis is a type of lumbar spinal stenosis that can be treated with full-endoscopic spine surgery (FESS), especially in patients with stable isthmic spondylolisthesis at L5.
  • The article outlines the process for achieving complete decompression, emphasizing the importance of visualizing the "pars crisscross" structure during the procedure.
  • The step-by-step method involves docking an 8 mm cannula, removing specific bone structures, and confirming decompression of the L5 nerve root, making it the first detailed guide for this surgery under local anesthesia.
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Risk Factors for Early Subsidence of 3D-Printed Artificial Vertebral After Anterior Cervical Corpectomy and Fusion.

World Neurosurg

November 2024

Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, China. Electronic address:

Article Synopsis
  • The study investigates the early subsidence of 3D-printed artificial vertebral bodies (3D-PAVB) following anterior cervical corpectomy and fusion (ACCF), which can lead to serious complications like spinal cord compression and neurological issues.
  • Researchers analyzed data from 66 patients with cervical spondylosis to identify risk factors associated with this subsidence, finding that 28.8% experienced this issue post-surgery.
  • Key factors such as age, diabetes, smoking status, and lower CT values of the vertebral body significantly contributed to the risk of subsidence, with results indicating substantial improvements in clinical outcomes regardless of subsidence status.
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Study Design: Retrospective cohort study.

Objective: Although there are several methods available to assess upper limb function in patients with cervical spondylotic myelopathy, few methods can evaluate the degree of upper limb functional impairment in activities of daily living.

Summary Of Background Data: We devised and evaluated the utility of a new assessment method called the 10 Coins Test, which is based on daily movements.

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Objective: To analyze the influencing factors and treatment options of cervical spondylotic myelopathy (CSM) complicated with traumatic central cord syndrome (TCCS).

Methods: A total of 243 patients with CSM admitted to our hospital from January 2021 to September 2022 were retrospectively analyzed, and then divided into the control group (n = 152) and the observation group (n = 91) according to the presence or absence of concurrent TCCS. The clinical data and imaging data of the two groups were compared, and multivariate logistic regression was used to analyze the influencing factors of CSM complicated with TCCS.

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Background: Axial symptoms (AS) represent one of the primary complications after cervical spondylotic myelopathy (CSM) surgery. Traditional Chinese Medicine (TCM), as a complementary and alternative therapy, is widely used in the treatment of postoperative AS in CSM. However, it lacks standardised treatment protocols, uniform therapeutic criteria, assessment methods and a sufficiently in-depth understanding of its mechanisms of action.

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3D Printing for Personalized Solutions in Cervical Spondylosis.

Orthop Res Rev

October 2024

Orthopaedic Clinical Research Center, The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia Autonomous Region, People's Republic of China.

In the context of the digital revolution, 3D printing technology brings innovation to the personalized treatment of cervical spondylosis, a clinically common degenerative disease that severely impacts the quality of life and increases the economic burden of patients. Although traditional surgeries, medications, and physical therapies are somewhat effective, they often fail` to meet individual needs, thus affecting treatment adherence and outcomes. 3D printing, with its customizability, precision, material diversity, and short production cycles, shows tremendous potential in the treatment of cervical spondylosis.

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Background: Data on equine thoracic pathology hardly exist in breeds other than Thoroughbreds.

Objectives: To describe pathological changes of the osseous thoracic vertebral column in Warmblood horses, Shetland ponies and Konik horses, and to compare prevalence and severity.

Study Design: Descriptive post-mortem study.

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Study Design: Retrospective cross-sectional study.

Purpose: To investigate the size and local anatomy of the right and the left-sided oblique corridors between L1-L5 levels and identify the potential impact of increasing age and sex on corridor size.

Overview Of Literature: The oblique lumbar interbody fusion (OLIF) was introduced by Silvestre and his colleagues as a solution to the approach-related complications associated with anterior lumbar interbody fusion and lateral lumbar interbody fusion.

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Spondylolysis in Adolescent Athletes: A Descriptive Study of 533 Patients.

Clin J Sport Med

October 2024

Sports Medicine Division, Department of Orthopaedics, West Virginia University, Morgantown, West Virginia.

Objective: The objective of this descriptive study was to evaluate spondylolysis in adolescent athletes, including age at time of injury, sport associated with injury, examination findings, site of injury, studies used for diagnosis, treatments, duration of treatment, and outcomes.

Design: This was a retrospective chart review of patients who presented with a diagnosis of spondylolysis over a 17-year period.

Setting: Community primary care sports medicine practice.

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Background: Internal carotid artery (ICA) dissection is a relatively rare cause of acute ischemic stroke. Stretching and compression of ICA due to sudden acceleration, deceleration, and rotational forces are risk factors for ICA dissection. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is believed to trigger an inflammatory response that exacerbates endothelial dysfunction and leads to arterial dissection.

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Background: Computed tomography (CT) of the axial skeleton is increasing across many equine hospitals. CT of the pelvis and caudal spine in a large group of clinical cases has not been reported previously.

Objective: To describe the pathological lesions identified in the caudal spine/pelvis in horses and ponies undergoing CT spine of this region.

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Article Synopsis
  • This study compared the effectiveness of two surgical procedures, anterior spinal fusion (ASF) and posterior cervical foraminotomy (PCF), in helping patients recover motor function after surgery for cervical spondylotic radiculopathy (CSR).
  • A total of 227 patients were evaluated, with 106 focusing specifically on those with upper-limb motor deficits, and their recovery was monitored for at least 12 months post-surgery.
  • Results indicated that while the overall recovery rates were similar (74% for ASF and 86% for PCF), the PCF group recovered motor function significantly faster at 3, 6, and 12 months compared to the ASF group, suggesting PCF may be the better option for quicker recovery
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Objective: Despite efforts toward achieving gender-based equality in clinical trial enrollment, females are frequently underrepresented and gender-specific data analysis is lacking. Identifying and addressing gender bias in medical decision-making and outcome reporting may facilitate more equitable healthcare delivery. This study aimed to determine if gender differences exist in the clinical evaluation and surgical management of patients with degenerative lumbar conditions.

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Objective: The aim of this study was to compare the clinical efficacy of the full-endoscopic posterior cervical foraminotomy (FE-PCF) and the unilateral biportal endoscopic posterior cervical foraminotomy (UBE-PCF) in the treatment of cervical spondylotic radiculopathy (CSR).

Methods: Patients who underwent posterior cervical spine surgery in our hospital from January 2020 to December 2022 were retrospectively analyzed. According to the surgical method, the patients were divided into two groups: FE-PCF group and UBE-PCF group.

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  • This study examined the demographics and comorbidities of patients with narcolepsy by analyzing electronic health records (EHR) using natural language processing (NLP) algorithms, marking a novel approach in this area.
  • Researchers identified 2,057 narcolepsy patients at the Mayo Clinic from 2000 to 2020 and compared them with a matched control group, focusing on various comorbid conditions.
  • The findings revealed that narcolepsy patients have higher instances of sleep disorders, mood disorders, and pain-related conditions, indicating that their challenges extend beyond just narcolepsy symptoms.
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  • - The study aimed to investigate how electroacupuncture (EA) affects the activation of astrocytes and the HMGB1/TLR4/MyD88 signaling pathway in rats with cervical spondylosis radiculopathy (CSR), to better understand its pain-relieving mechanisms.
  • - Twenty-four male SD rats were divided into four groups: blank, sham surgery, model, and EA, with the EA treatment applied to specific acupoints for 20 minutes daily over a week, followed by various assessments of pain and tissue samples for protein and cytokine analysis.
  • - Results showed that the model group had significant pain and inflammation markers compared to the sham group, with EA treatment helping to normalize some of these parameters, suggesting
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  • The study aimed to investigate how wheat-grain moxibustion affects autophagy and endoplasmic reticulum stress (ERS) in rats with cervical spondylotic radiculopathy (CSR), focusing on its potential to ease neuropathic pain.
  • Forty-eight rats were divided into four groups to assess the effects of wheat-grain moxibustion and its combined use with a substance called 3-methyladenine (3MA), with treatments administered daily for a week following CSR model establishment.
  • Results showed significant increases in gait disturbance scores and decreases in pain thresholds in the treatment groups compared to the sham group, indicating potential benefits of moxibustion on pain relief and related mechanisms.
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Article Synopsis
  • Renal cell carcinoma (RCC) is the most common type of kidney cancer and can spread to other parts of the body, including the spine, leading to serious neurological problems that require quick medical action.
  • An 86-year-old man with a history of RCC experienced lower limb weakness due to a spinal lesion, which was surgically removed and confirmed as metastatic RCC; he later improved with additional therapies but died three months later.
  • The case highlights the need for thorough imaging to diagnose spinal issues accurately, the value of a collaborative healthcare approach for treatment, and the importance of following postoperative care guidelines to avoid complications.
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Characteristics of Lumbar Pars Interarticularis and Pedicle Stress Injuries by Sport in 902 Pediatric and Adolescent Athletes: A Retrospective Study.

Am J Sports Med

November 2024

Division of Sports Medicine, Department of Orthopedics and Sports Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Article Synopsis
  • Research indicates a higher prevalence of upper lumbar spondylolysis in young athletes than previously thought, highlighting a lack of sport-specific studies on this condition.
  • The study aimed to identify risk factors associated with upper lumbar stress injuries in pediatric and adolescent athletes by reviewing medical records from two academic centers.
  • Results showed that the majority of diagnosed athletes had lower level injuries, while a smaller percentage experienced upper level injuries, which were linked to being older at diagnosis and shorter durations of low back pain.
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  • * A retrospective CT scan study on 324 dogs found that 21% had presumed EPJF and another 21% had annulus fibrosus rupture (AFF), which were often located at the last lumbar vertebra’s caudal endplate.
  • * The study indicates that EPJF is linked to more severe IVDH grades and factors like age and certain spinal conditions, suggesting a need for further research to clarify its clinical significance and relationship to other spinal issues.
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  • The study explores the impact of revision surgery on patient-reported outcomes (PROs) following initial surgeries for grade 1 spondylolisthesis, comparing decompression-only and decompression plus fusion (D+F) treatments.
  • Data was collected from over 600 patients, revealing that 13.3% of decompression-only patients and 9.8% of D+F patients required revision surgery within 5 years, with revision patients reporting worse outcomes.
  • The findings indicate that while revision surgery affects PROs adversely, patients undergoing D+F see a more significant decline in their reported outcomes compared to those who only had decompression surgery.
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Three dimensional-printed artificial disc replacement for single-level cervical spondylosis: a cohort study.

Int Orthop

January 2025

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.

Article Synopsis
  • This study compares the effectiveness of 3D-printed artificial discs (CADR) versus anterior cervical discectomy and fusion (ACDF) in treating cervical spondylosis in 73 patients.
  • Both methods showed significant improvement in clinical symptoms, but CADR resulted in better postoperative range of motion (ROM) and fewer adverse effects.
  • The findings suggest that 3D-printed artificial discs provide a safer and more effective treatment option, with less blood loss and a lower incidence of additional surgery for complications compared to ACDF.
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