33 results match your criteria: "Cerrahpasa Institute of Cardiology[Affiliation]"

Introduction: The Naples prognostic score (NPS) is a novel indicator of nutritional and inflammatory statuses in cancer patients. Development of atrial fibrillation after cardiac surgery (POAF) is a common complication that increases the incidence of adverse events. Numerous studies have investigated predictors of POAF.

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This study evaluated the management of dyslipidemia in Turkey with the goal of understanding current diagnosis and treatment patterns, as well as identifying unmet needs in achieving effective low-density lipoprotein cholesterol (LDL-C) targets. Using a Delphi panel consisting of nine expert cardiologists, the study reveals key gaps in dyslipidemia management, particularly in the underutilization of combination therapies, such as statins and PCSK9 inhibitors, which are crucial for achieving LDL-C targets in high-risk patients. The findings indicate that while many patients with very high cardiovascular risk are diagnosed, a significant proportion do not receive optimal treatment to reach LDL-C levels recommended by European guidelines.

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Article Synopsis
  • Acute kidney injury (AKI) is a frequent issue in chronic kidney disease (CKD) patients in cardiac ICUs, prompting a study to find predictors for AKI in this population.
  • The MORCOR-TURK trial involved over 3,100 patients, with 615 CKD patients analyzed; AKI occurred in 46% of these patients during their hospital stay.
  • Key predictors for developing AKI included decompensated heart failure, types of coronary interventions, elevated troponin levels, and the need for mechanical ventilation, suggesting the need for personalized treatment strategies to prevent AKI.
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  • The study investigates the impact of severe pulmonary hypertension and low TAPSE values on the early mortality and morbidity of patients undergoing mitral valve replacement due to rheumatic conditions.
  • It analyzes data from 79 patients, finding significant differences in outcomes (e.g., tricuspid regurgitation and mortality rates) between those with high pulmonary artery pressure (PAP ≥ 50) compared to those with lower levels.
  • The authors suggest that timely surgical intervention could improve survival rates in patients with mitral valve issues before pulmonary pressure increases and right ventricular function worsens.
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This study aimed to identify the phenotypic features contributing to the development of left ventricular outflow tract obstruction (LVOTO) in patients with hypertrophic cardiomyopathy (HCM) and to evaluate the genotype‒phenotype relationship. This cross-sectional study included 96 patients diagnosed with HCM (mean age: 56.9 ± 13.

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Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study.

ESC Heart Fail

September 2024

Department of Cardiology, İzmir University of Economics, Faculty of Medicine, Medical Point Hospital, İzmir, Türkiye.

Aims: We aimed to determine the use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and to identify clinical factors associated with their use in patients with heart failure (HF) in a real-life setting.

Methods: Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study is a multicentre, cross-sectional and observational study that included HF patients in the outpatient setting regardless of ejection fraction from 19 cardiology centres between August 2023 and December 2023.

Results: The study population consisted of 1923 patients with HF, predominantly men (61.

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Background And Aim: High-dose statin therapy before percutaneous coronary intervention (PCI) is thought to reduce the occurrence of Peri-procedural Myocardial Infarction (PPMI), which is associated with increased mortality and prolonged hospitalization, especially in statin naïve patients. This study aims to investigate the effect of rosuvastatin loading dose on PPMI and major adverse cardiac and cerebrovascular events (MACCE) in patients undergoing elective PCI, considering their statin use.

Methods: One hundred sixty-five patients with stable coronary artery disease (CAD) without heart failure (HF) or chronic kidney disease (CKD) were included in the study.

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Background: It has been demonstrated that there is a significant reduction in the incidence of cardiovascular events, mortality rates, and worsening kidney disease in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i). However, there is limited information about the effect of SGLT2i on the incidence of contrast-induced acute kidney injury (CI-AKI) in patients undergoing primary percutaneous intervention (pPCI).

Aims: Our research was focused on examining how SGLT2i exposure impacts CI-AKI occurrence in patients with ST-segment elevation myocardial infarction (STEMI) and undergoing pPCI.

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Background: Convalescent plasma (CP) therapy can be defined as a passive immunity transfer approach involving the administration of plasma for therapeutic purposes to inpatients hospitalized due to an active virus infection. Passive immunity antibodies can reduce target organ damage and directly neutralize the responsible pathogens. A limited number of studies on the use of CP have reported that critically ill patients can benefit from CP therapy.

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Pulmonary hypertension (PH) is a major health problem with increasing awareness. Although most common cause of PH is left heart disease (Group 2 PH), life-threatening complications occur mostly in Group 1 (pulmonary arterial hypertension) and Group 4 (chronic thromboembolic PH) patients. Although external compression of the left main coronary artery (LMCA) due to pulmonary artery dilatation is rare, it is a life-threatening complication since it causes myocardial ischemia and sudden cardiac death.

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Study Objective: To investigate the efficacy of the perfusion index in assessing block success in pediatric patients undergoing elective supracondylar fracture repair surgery.

Methods: It was a retrospective study in a tertiary-care center. Twenty-eight pediatric supracondylar humerus fracture patients who underwent elective surgery for fracture repair were evaluated.

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Background: Gender-related clinical variations in patients with acute heart failure have been described in previous studies. However, there is still a lack of research on gender differences in patients hospitalized for acute heart failure in Türkiye. The aim of this study is to compare the clinical features, in-hospital approaches, and outcomes of male and female patients hospitalized for acute heart failure.

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Pulmonary arterial hypertension is still a fatal disease persisting with poor prognosis, despite all the advances in treatment (new agents and new combination strategies) in recent years. Patients present with different symptoms which are not specific to the disease (dyspnea, angina, palpitation, and syncope). Angina may occur secondary to myocardial ischemia due to increased right ventricular after load (oxygen supply and demand mismatch) or external compression on the left main coronary artery.

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Background: Despite advances in therapeutic management of patients with heart failure, there is still an increasing morbidity and mortality all over the world. In this study, we aimed to present the 3-year follow-up outcomes of patients included in the Journey HF-TR study in 2016 that has evaluated the clinical characteristics and management of patients with acute heart failure admitted to the hospital and present a national registry data.

Methods: The study was designed retrospectively between November 2016 and December 2019.

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Article Synopsis
  • The study explores the effectiveness of SYNTAX Score II (SS-II) in predicting mortality for patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (p-PCI).
  • Researchers analyzed data from 743 STEMI patients, grouping them into low, mid, and high SS-II categories to examine in-hospital and long-term mortality rates.
  • Findings revealed that patients in the high SS-II group had significantly higher rates of in-hospital (15%) and all-cause mortality (32.2%), establishing SS-II >31 as a strong independent predictor of mortality risk.
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Introduction: Classic coronary artery bypass grafting (CABG) surgery involves diastolic cardiac arrest under cardiopulmonary bypass, while off-pump CABG (OPCABG) has become widespread in recent years.

Methods: 174 patients who underwent OPCABG were included in the study. Patients were divided into two groups.

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Background: Mechanical ventilation may be particularly challenging in obese patients undergoing laparoscopic bariatric surgery. The present study aimed to compare the effects of pressure-controlled ventilation (PCV) with those of volume-controlled ventilation (VCV) on peripheral tissue oxygenation (PTO), respiratory function, hemodynamic status, and ventilation-related complications in patients undergoing laparoscopic bariatric surgery.

Methods: A total of 100 patients with obesity who underwent gastric plication or sleeve gastrectomy were recruited for the study, and 60 patients (n=32, in group PCV; n=28, in group VCV) were ultimately enrolled.

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Aim: In this study, we aimed to investigate the effect of vacuum-assisted closure therapy on venous stasis wound healing in patients with chronic venous leg ulcers.

Methods: Vacuum-assisted closure therapy was applied on a total of 14 venous leg ulcers. All patients had post-thrombotic syndrome.

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Mitral annular disjunction (MAD) is a structural abnormality defined as the separation of the ventricular myocardium between the mitral valve annulus and the left atrial wall. It is present in some patients with mitral valve prolapse (MVP) and is associated with papillary muscle fibrosis and ventricular arrhythmia. Although it is easy to diagnose, it can be overlooked in daily practice.

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Article Synopsis
  • The study evaluated the predictive value of the C-reactive protein/albumin ratio (CAR) for acute kidney injury (AKI) in non-ST-segment elevation myocardial infarction (NSTEMI) patients with chronic kidney disease (CKD).
  • A total of 420 NSTEMI patients were analyzed, and it was found that a higher CAR ratio (especially in the T3 group) significantly correlated with an increased incidence of AKI, with 34% of T3 patients developing AKI.
  • The study highlighted that CAR is a promising indicator for predicting AKI in this patient population, with CAR levels above 0.20 showing 74% sensitivity and 45% specificity for AKI development.
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Impact of the COVID-19 pandemic on hospitalizations for acute coronary syndromes: a multinational study.

QJM

November 2021

Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Anesthesia and Intensive Care, Fondazione Policlinico San Matteo Hospital IRCCS, Pavia, Italy.

Background: COVID-19 has challenged the health system organization requiring a fast reorganization of diagnostic/therapeutic pathways for patients affected by time-dependent diseases such as acute coronary syndromes (ACS).

Aim: To describe ACS hospitalizations, management, and complication rate before and after the COVID-19 pandemic was declared.

Design: Ecological retrospective study.

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Objective: The performance of coronary bypass grafting (CBG) induces a type of subclinical systemic inflammatory response syndrome. The present study was performed to examine the changes in pentraxin 3 (PTX3) and oxidative parameters during cross-clamping in patients undergoing CBG. We also examined factors affecting the development of postoperative atrial fibrillation (POAF).

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