266 results match your criteria: "Centro Universitario de la Defensa[Affiliation]"

Secure Base Leadership in military training: enhancing organizational identification and resilience through work engagement.

Front Psychol

December 2024

Department of Social and Organizational Psychology, Faculty of Psychology, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.

Introduction: This study examines the relationships between secure base leadership, organizational identification, and resilience among military cadets, utilizing the Job Demands-Resources (JD-R) model as a theoretical framework. Specifically, it explores the mediating role of work engagement in these associations within the context of military training.

Methods: A cross-sectional study was conducted with 363 cadets from the General Military Academy of the Army in Zaragoza, Spain.

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A Study of the Optimal Logic Combinations of RO-Based PUFs on FPGAs to Maximize Identifiability.

Sensors (Basel)

December 2024

Group of Electronic Design (GDE), Aragón Institute of Engeneering Research (I3A), University of Zaragoza, 50009 Zaragoza, Spain.

One of the challenges that wireless sensor networks (WSNs) need to address is achieving security and privacy while keeping low power consumption at sensor nodes. Physically unclonable functions (PUFs) offer a challenge-response functionality that leverages the inherent variations in the manufacturing process of a device, making them an optimal solution for sensor node authentication in WSNs. Thus, identifiability is the fundamental property of any PUF.

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Quantum Effects Explain the Twist Angle in the Helical Structure of DNA.

Chemphyschem

October 2024

Centro Universitario de la Defensa, Academia General del Aire, Universidad Politécnica de Cartagena, C/Coronel López Peña S/N, Santiago de La Ribera, 30720, Murcia, Spain.

Why are DNA bases stacked in a double helix structure? We combined three theoretical approaches to demonstrate how one core concept derived from quantum mechanics (Pauli repulsion) annihilates the contribution of dispersion to the π-π stacking. The helical architecture is governed by a combination of exchange and electrostatic forces, a result that is interpreted from both a computational and a biological perspective.

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LED spectrophotometry is a robust technique for the indirect characterization of wastewater pollutant load through correlation modeling. To tackle this issue, a dataset with 1300 samples was collected, from both raw and treated wastewater from 45 wastewater treatment plants in Spain and Chile collected over 4 years. The type of regressor, scaling, and dimensionality reduction technique and nature of the data play crucial roles in the performance of the processing pipeline.

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Development of Chitosan Polysaccharide-Based Magnetic Gel for Direct Red 83:1 Removal from Water.

Gels

July 2024

Molecular Recognition and Encapsulation Research Group (REM), Health Sciences Department, Universidad Católica de Murcia (UCAM), Campus de los Jerónimos 135, E-30107 Guadalupe, Spain.

Water pollution caused by dyes is a significant environmental issue, necessitating the development of effective, cost-efficient decolorization methods suitable for industrial use. In this study, a Chitosan-Fe polymeric gel was synthesized, characterized, and tested for removing the azo dye Direct Red 83:1 from water. The polymeric magnetic chitosan was analyzed using various techniques: Field Emission Scanning Electron Microscopy (FE-SEM) revealed a porous structure, Differential Scanning Calorimetry (DSC) and Thermal Gravimetric Analysis (TGA) demonstrated the thermal stability, Infrared Spectrophotometry (IR) indicated the successful coordination of iron at the C3 position, and X-ray Powder Diffraction (XRD) confirmed the crystalline nature of the polymeric structure.

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Forest disturbance regimes and trends in continental Spain (1985-2023) using dense landsat time series.

Environ Res

December 2024

Environmental Remote Sensing Research Group, Department of Geography and Geology, Universidad de Alcalá, Colegios 2, Alcalá de Henares, 28801, Spain.

Forest disturbance regimes across biomes are being altered by interactive effects of global change. Establishing baselines for assessing change requires detailed quantitative data on past disturbance events, but such data are scarce and difficult to obtain over large spatial and temporal scales. The integration of remote sensing with dense time series analysis and cloud computing platforms is enhancing the ability to monitor historical disturbances, and especially non-stand replacing events along climatic gradients.

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An agent-based method to estimate 3D cell migration trajectories from 2D measurements: Quantifying and comparing T vs CAR-T 3D cell migration.

Comput Methods Programs Biomed

October 2024

Department of Mechanical Engineering, Multiscale in Mechanical and Biological Engineering (M2BE), Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain. Electronic address:

Background And Objective: Immune cell migration is one of the key features that enable immune cells to find invading pathogens, control tissue damage, and eliminate primary developing tumors. Chimeric antigen receptor (CAR) T-cell therapy is a novel strategy in the battle against various cancers. It has been successful in treating hematological tumors, yet it still faces many challenges in the case of solid tumors.

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An agent-based model for cell microenvironment simulation using FLAMEGPU2.

Comput Biol Med

September 2024

Department of Computer Science and Insigneo Institute of in Silico Medicine, University of Sheffield, Sheffield, UK. Electronic address:

This work presents an advanced agent-based model developed within the FLAMEGPU2 framework, aimed at simulating the intricate dynamics of cell microenvironments. Our primary objective is to showcase FLAMEGPU2's potential in modelling critical features such as cell-cell and cell-ECM interactions, species diffusion, vascularisation, cell migration, and/or cell cycling. By doing so, we provide a versatile template that serves as a foundational platform for researchers to model specific biological mechanisms or processes.

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Long-term annual estimation of forest above ground biomass, canopy cover, and height from airborne and spaceborne sensors synergies in the Iberian Peninsula.

Environ Res

October 2024

Centro Universitario de la Defensa de Zaragoza, Academia General Militar, Ctra. de Huesca s/n, Zaragoza 50090, Spain; GEOFOREST-IUCA, Departamento de Geografía, Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.

The Mediterranean Basin has experienced substantial land use changes as traditional agriculture decreased and population migrated from rural to urban areas, which have resulted in a large forest cover increase. The combination of Landsat time series, providing spectral information, with lidar, offering three-dimensional insights, has emerged as a viable option for the large-scale cartography of forest structural attributes across large time spans. Here we develop and test a comprehensive framework to map forest above ground biomass, canopy cover and forest height in two regions spanning the most representative biomes in the peninsular Spain, Mediterranean (Madrid region) and temperate (Basque Country).

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Unlabelled: Society's support upon chemicals over the last few decades has led to their increased production, application and discharge into the environment. Wastewater treatment plants (WWTPs) contain a multitude of these chemicals such us; pharmaceutical compounds (PCs). Often, their biodegradability by activated sludge microorganisms is significant for their elimination during wastewater treatment.

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Aging induces cardiac remodeling, resulting in an increase in the risk of suffering heart diseases, including heart failure. Collagen deposition increases with age and, together with sarcomeric changes in cardiomyocytes, may lead to ventricular stiffness. Multiphoton (MP) microscopy is a useful technique to visualize and detect variations in cardiac structures in a label free fashion.

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In this paper, a six-degree-of-freedom analog tactile probe with a new, simple, and robust mechanical design is presented. Its design is based on the use of one elastomeric ring that supports the stylus carrier and allows its movement inside a cubic measuring range of ±3 mm. The position of the probe tip is determined by three low-cost, noncontact, 2D PSD (position-sensitive detector) sensors, facilitating a wider application of this probe to different measuring systems compared to commercial ones.

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Article Synopsis
  • Nitrogen fixation is a crucial chemical reaction that typically requires specific catalysts and harsh conditions, but this study reveals that exposing black phosphorus to air allows for nitrogen fixation at low levels (up to 100 ppm).
  • Interestingly, this nitrogen fixation process not only occurs in exfoliated black phosphorus but also in non-exfoliated and other forms of phosphorus, indicating it’s linked to the oxidation of phosphorus rather than its specific structure.
  • Although the amount of nitrogen fixed is low, this finding could have significant implications for understanding phosphorus chemistry, environmental stability, and future catalyst design for nitrogen fixation.
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This study's primary objective was to identify individuals whose physiological responses deviated from the rest of the study population by automatically monitoring atmospheric pressure levels to which they are exposed and using parameters derived from their heart rate variability (HRV). To achieve this, 28 volunteers were placed in a dry hyperbaric chamber, where they experienced varying pressures from 1 to 5 atmospheres, with five sequential stops lasting five minutes each at different atmospheric pressures. The HRV was dissected into two components: the respiratory component, which is linked to respiration; and the residual component, which is influenced by factors beyond respiration.

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Effects of a multicomponent training followed by a detraining period on metabolic syndrome profile of older adults.

Exp Gerontol

February 2024

GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, 50009 Zaragoza, Spain; Instituto Agroalimentario de Aragón (IA2), University of Zaragoza, 50013 Zaragoza, Spain; Department of Physiatry and Nursery, Faculty of Health Sciences, University of Zaragoza, 50009 Zaragoza, Spain; Red Española de Investigación en Ejercicio Físico y Salud, EXERNET, University of Zaragoza, 50009 Zaragoza, Spain; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address:

Aims: The present study sought to analyze the effects of 6-month multicomponent training (MCT) combined with a 4-month detraining on metabolic syndrome (MetS) profile among older adults with decreased functional capacity.

Methods: This quasi-experimental study included a total of 104 older adults (80.5 ± 6.

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Interindividual Age-Independent Differences in Human CX43 Impact Ventricular Arrhythmic Risk.

Research (Wash D C)

November 2023

Biomedical Signal Interpretation and Computational Simulation group (BSICoS), Aragón Institute of Engineering Research, University of Zaragoza, Zaragoza 50018, Spain.

Connexin 43 (CX43) is one of the major components of gap junctions, the structures responsible for the intercellular communication and transmission of the electrical impulse in the left ventricle. There is limited information on the histological changes of CX43 with age and their effect on electrophysiology, especially in humans. Here, we analyzed left ventricular biopsies from living donors starting at midlife to characterize age-related CX43 remodeling.

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This study aims to investigate the impact of hormonal imbalances during menopause, compounded by the natural ageing process, on bone health. Specifically, it examines the effects of increased bone turnover and focal bone balance on bone mass. A three-dimensional computational bone remodeling model was employed to simulate the response of the femur to habitual loads over a 19-year period, spanning premenopause, menopause, and postmenopause.

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Integrating bioavailability measurements in persistence testing of partially biodegradable organic chemicals in soil.

Sci Total Environ

January 2024

Instituto de Recursos Naturales y Agrobiología (IRNAS), C.S.I.C., Avenida Reina Mercedes, 10, E-41012 Seville, Spain. Electronic address:

Overestimation of risk is one of the main problems in environmental risk assessments if only total concentration of organic pollutants is considered. In this study, we integrated bioavailability measurements into persistence testing of pollutants in soil to show that it is the key to have a more realistic environmental risk assessment (ERA). To this integration, two standardized methods were used: OECD 307, as persistence test, and ISO 16751: 2020, to bioavailability measurements based on 20 h extractions with a strong adsorbent (Tenax), using pyrene and carbamazepine as model test substances.

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New heterometallic binuclear and trinuclear platinum(IV)-gold(I) compounds of the type [Pt(L) Cl (OH){(OOC-4-C H -PPh )AuCl} ] (L=NH , n=2; x=1, 2; L=diaminocyclohexane, DACH, n=1; x=2) are described. These compounds are cytotoxic and selective against a small panel of renal, bladder, ovarian, and breast cancer cell lines. We selected a trinuclear PtAu compound containing the Pt core based on oxaliplatin, to further investigate its cell-death pathway, cell and organelle uptake and anticancer effects against the triple-negative breast cancer (TNBC) MDA-MB-231 cell line.

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Effects of tumour heterogeneous properties on modelling the transport of radiative particles.

Int J Numer Method Biomed Eng

November 2023

Mechanical Engineering Department, Multiscale in Mechanical and Biological Engineering, Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Spain.

Dose calculation plays a critical role in radiotherapy (RT) treatment planning, and there is a growing need to develop accurate dose deposition models that incorporate heterogeneous tumour properties. Deterministic models have demonstrated their capability in this regard, making them the focus of recent treatment planning studies as they serve as a basis for simplified models in RT treatment planning. In this study, we present a simplified deterministic model for photon transport based on the Boltzmann transport equation (BTE) as a proof-of-concept to illustrate the impact of heterogeneous tumour properties on RT treatment planning.

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Article Synopsis
  • - The isomerization reaction converting terminal alkenes to internal alkenes can be driven by very small amounts (part-per-million) of various Ru (ruthenium) sources when using a pure terminal alkene.
  • - The initial soluble Ru sources transform into active Ru(II) species during the reaction, which are responsible for the isomerization observed.
  • - The results support a Finke-Watzky mechanism for how these catalytically active species are formed, which may also be relevant for understanding other Ru-catalyzed processes like alkene metathesis.
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The rise of mechanical metamaterials: Auxetic constructs for skin wound healing.

J Tissue Eng

June 2023

Multiscale in Mechanical and Biological Engineering, Aragon Institute of Engineering Research (I3A), University of Zaragoza, Zaragoza, Aragon, Spain.

Auxetic materials are known for their unique ability to expand/contract in multiple directions when stretched/compressed. In other words, they exhibit a negative Poisson's ratio, which is usually positive for most of materials. This behavior appears in some biological tissues such as human skin, where it promotes wound healing by providing an enhanced mechanical support and facilitating cell migration.

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On-chip monitoring of toxic gases: capture and label-free SERS detection with plasmonic mesoporous sorbents.

Lab Chip

July 2023

Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain.

Article Synopsis
  • * This study focuses on creating robust and reusable SERS microfluidic chips to help first responders identify neurotoxic gases accurately and quickly, emphasizing important features like detection limits, response time, and reusability.
  • * The research includes developing a special 3D structure using mesoporous silica and gold nanoparticles which enhances gas detection performance, specifically evaluating its effectiveness with DMMP, a neurotoxic simulant, under various conditions.
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β-Cyclodextrins as affordable antivirals to treat coronavirus infection.

Biomed Pharmacother

August 2023

Cell Structure Lab, Centro Nacional de Biotecnologia, CNB - CSIC, Campus de Cantoblanco, 28049 Madrid, Spain. Electronic address:

The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. Starting from a list of 116 drug candidates, we used molecular modelling tools to rank the 44 most promising inhibitors.

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Diving can have significant cardiovascular effects on the human body and increase the risk of developing cardiac health issues. This study aimed to investigate the autonomic nervous system (ANS) responses of healthy individuals during simulated dives in hyperbaric chambers and explore the effects of the humid environment on these responses. Electrocardiographic- and heart-rate-variability (HRV)-derived indices were analyzed, and their statistical ranges were compared at different depths during simulated immersions under dry and humid conditions.

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