875 results match your criteria: "Centro Hospitalar de Vila Nova de Gaia-Espinho[Affiliation]"

Delays have dangerous ends: Tuberculosis diagnosis delay in Portugal, a qualitative study.

Pulmonology

February 2024

EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal; Laboratório para a Investigação Integrativa e Translacional em Saúde Populacional (ITR), Porto, Portugal; Estudo das Populações, ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal; Faculdade de Psicologia e Ciências da Educação, Universidade do Porto, Porto. Portugal.

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Purpose: Physical exercise has positive effects on clinical outcomes of breast cancer survivors such as quality of life, fatigue, anxiety, depression, body mass index, and physical fitness. We aimed to study its impact on immune, inflammatory, cardiometabolic, and fatty acids (FA) biomarkers.

Methods: An exploratory sub-analysis of the MAMA_MOVE Gaia After Treatment trial (NCT04024280, registered July 18, 2019) was performed.

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Article Synopsis
  • - The study focused on identifying factors that contribute to prolonged survival in cancer patients admitted to palliative care, specifically those living over one year after admission.
  • - Researchers conducted a retrospective case-control study using electronic records from 2012 to 2018, comparing data from patients who survived over a year to those who survived 6 months or less, identifying 1721 total patients.
  • - Key findings indicated that higher hemoglobin levels and specific creatinine levels positively correlated with longer survival, while conditions like abnormal cognition and liver metastases were linked to shorter lifespans; further research is needed to confirm these results.
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Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial.

Radiology

February 2024

School of Cardiovascular and Metabolic Health, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (R.S., D.C., C.B., C.D.); Golden Jubilee National Hospital, Clydebank, United Kingdom (D.C., C.B.); Heart and Vascular Center, Semmelweis University, Budapest, Hungary (B.M., P.M.H., T. Bárány, B.S., M.V.N.); Departments of Cardiology (K.F.K., A.D.K.) and Radiology (K.F.K., A.D.K.), Copenhagen University Hospital-Rigshospitalet & Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom (P.D., C.O., S. Kelly, S.R.); Department of Cardiology, Hospital Universitario Vall d'Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain (J.R.P., F.X.V., B.G.d.B.); Centro de Investigación Biomédica en Red, Madrid, Spain (J.R.P., F.X.V., B.G.d.B.); Department of Cardiology, Paul Stradins Clinical University Hospital, Riga, Latvia (A.E.); University of Latvia, Riga, Latvia (A.E.); Department of Cardiology, Motol University Hospital, Prague, Czech Republic (J.V., M.H.); Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (G.Š.); Department of Cardiology, Hospital of Lithuanian University of Health Sciences, Kaunas, Lithuania (G.Š.); Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia (N.Č.A., F.A.); Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia (N.Č.A., F.A.); Department of Radiology, University of Leipzig Heart Centre, Leipzig, Germany (M.G.); Department of Radiology, St. Vincent's University Hospital, Dublin, Ireland (J.D.D.); School of Medicine, University College Dublin, Dublin, Ireland (J.D.D.); Department of Cardiology, Basurto Hospital, Bilbao, Spain (I.D., A.R.); Departments of Cardiology (G.D.) and Radiology (E.T.), Aintree University Hospital, Liverpool, United Kingdom; Edge Hill University, Ormskirk, United Kingdom (G.D.); Department of Radiology, Charité-Universitätsmedizin Berlin Campus Mitte, Charitéplatz 1, Freie Universität Berlin and Humboldt-Universität zu 10117 Berlin, Germany (E.Z., S.F., M. Mohamed, M.R., V.W., M.E., M.B., M.D.); National Institute of Cardiology, Warsaw, Poland (C. Kępka, M.K.); Department of Cardiology, Internal Medicine Clinic, Clinical Hospital Center Zemun, Belgrade, Serbia (R.V., A.Z.); Faculty of Medicine, University of Belgrade, Belgrade, Serbia (R.V.); Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy (M. Francone); Department of Biomedical Sciences, Humanitas University, Milan, Italy (M. Francone); Department of Cardiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland (M.I.S.); Department of Internal Medicine III, Department of Cardiology, Innsbruck Medical University, Innsbruck, Austria (F.P.); Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland (J.K.); Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia-Espinho, Vila Nova de Gaia, Portugal (R.F., V.G.R.); Department of Cardiology, Alb Fils Kliniken, Göppingen, Germany (S.S., T.D.); Department of Radiology, University of Cagliari, Cagliari, Italy (L.S.); Department of Cardiology, Royal Liverpool University Hospital, Liverpool, United Kingdom (B.R., M. Fisher); Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom (B.R., M. Fisher); Institute of Public Health, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (N.R.); ECRIN-ERIC (European Clinical Research Infrastructure Network-European Research Infrastructure Consortium), Paris, France (C. Kubiak); Department of Public Health, Section for Health Services Research, University of Copenhagen, Copenhagen, Denmark (K.S.H.); Bavarian Cancer Registry, Bavarian Health and Food Safety Authority, Munich, Germany (J.M.N.); Department of Radiology, Medical Imaging Center, Semmelweis University, Budapest, Hungary (P.M.H.); Center of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, Targu Mures, Romania (I.B., I.R.); Department of Radiology, Paul Stradins Clinical University Hospital, Riga, Latvia (L.Z.); Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania (A.J.); Department of Radiology, Kaunas Clinics, Kaunas, Lithuania (A.J.); Department of Cardiology, University of Leipzig Heart Centre, Leipzig, Germany (M.W.); Department of Cardiology, St. Vincent's University Hospital, University College Dublin, Dublin, Ireland (S. Keane); Department of Radiology, Basurto Hospital, Bilbao, Spain (I.L.); Department of Cardiology and Angiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (M.L., H.D.); Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy (M. Mancone); Department of Radiology, Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland (D.K.); Department of Radiology, Innsbruck Medical University, Innsbruck, Austria (G.F.); Heart Center, Turku University Hospital and University of Turku, Turku, Finland (M. Pietilä); Administrative Centre, Health Care District of Southwestern Finland, Turku, Finland (M. Pietilä); Department of Radiology, University of Cagliari, Cagliari, Italy (M. Porcu); Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom (M. Fisher); Department of Cardiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Denmark (C.S.); Department of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Tirgu Mures, Romania (R.A.); Section of Cardiology, Department of Medicine, Copenhagen University Hospital of Glostrup, Glostrup, Denmark (J.A.); Department of Radiology, Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain (H.C.C.); Department of Cardiology, Nordsjaellands Hospital, Hillerod, Denmark (B.J.); Department of Internal Medicine, Clinic of Cardiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania (R.H., T. Benedek); DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany; Berlin Institute of Health, Berlin, Germany (H.D., M.D.); Berlin University Alliance, Berlin, Germany (M.D.); Department of Clinical Epidemiology and Applied Biostatistics, Universitätsklinikum Tübingen, Tübingen, Germany (L.M.S.H., P.M.); Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany (K.N.); Oregon Health & Science University, Portland, Ore (M. Ferencik); County Clinical Emergency Hospital Targu Mures, Targu Mures, Romania (T. Benedek); Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany (M.D.); and Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany (M.D.).

Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Purpose To compare initial use of CT versus invasive coronary angiography (ICA) on clinical outcomes in patients with stable chest pain stratified by BMI category. Materials and Methods This prospective study represents a prespecified BMI subgroup analysis of the multicenter Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial conducted between October 2015 and April 2019.

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Actinomycosis is a chronic, suppurative, granulomatous bacterial infection primarily associated with . The condition can be categorized into three distinct clinical types based on the affected anatomical region: cervicofacial, pulmonary, or abdominopelvic actinomycosis. The standard treatment for actinomycosis involves antibiotic therapy, with an empiric penicillin regimen as the first-line approach.

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Purpose: Since the beginning of 2023, ChatGPT emerged as a hot topic in healthcare research. The potential to be a valuable tool in clinical practice is compelling, particularly in improving clinical decision support by helping physicians to make clinical decisions based on the best medical knowledge available. We aim to investigate ChatGPT's ability to identify, diagnose and manage patients with otorhinolaryngology-related symptoms.

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Spinal cord injury without radiographic abnormality is a condition primarily observed in the pediatric population. However, its occurrence in adults remains underreported. This case report aims to describe a rare instance of adult spinal cord injury without neuroimaging abnormality (SCIWNA) following a road accident in a 52-year-old woman, emphasizing the clinical nuances and management challenges associated with this condition.

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Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study.

Br J Anaesth

April 2024

Department of Anaesthesiology, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany; CARID, Cardiovascular Research Institute Düsseldorf, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.

Article Synopsis
  • The 2022 European Society of Cardiology guidelines for preoperative evaluations aimed to improve the detection of pathological findings compared to the 2014 guidelines.
  • A study analyzed data from 15,529 patients and found that the updated recommendations changed testing protocols for many, but did not enhance the overall effectiveness of cardiac testing.
  • The use of B-type natriuretic peptide (NT-proBNP) for risk estimation did not improve pathological findings, and adherence to the new guidelines showed no significant link to major adverse cardiovascular events.
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Cultural factors play a significant role in shaping the perception of coercion during psychiatric admissions. The present study aimed to assess the psychometric properties of the Portuguese Admission Experience Survey(P-AES). The study employed a cross-sectional approach in five psychiatric departments in three regions of Portugal.

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The Role of 5-Hydroxymethylcytosine as a Potential Epigenetic Biomarker in a Large Series of Thyroid Neoplasms.

Endocr Pathol

March 2024

Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Rua Alfredo Allen 208, 4200-135, Porto, Portugal.

Cytosine modifications at the 5-carbon position play a critical role in gene expression regulation and have been implicated in cancer development. 5-Hydroxymethylcytosine (5hmC), arising from 5-methylcytosine (5-mC) oxidation, has shown promise as a potential malignancy marker due to its depletion in various human cancers. However, its significance in thyroid tumors remains underexplored, primarily due to limited data.

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Myoclonic epilepsy with ragged red fibers (MERRF) syndrome is a primary mitochondrial disorder characterized by myoclonus, epilepsy, ataxia, and muscle fiber abnormalities. While traditionally associated with neurological features, MERRF's multisystem nature extends to endocrine dysfunction, including diabetes mellitus, thyroid disorders, and adrenal abnormalities. This case report explores the multifaceted nature of MERRF syndrome by presenting the clinical journey of a 70-year-old woman who sought care at the endocrinology clinic due to coexisting Addison's disease and diabetes mellitus, marked by recurrent hypoglycemia and suboptimal metabolic control.

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Refining reconstructive arsenal: Free omental flap with autologous bone graft for complex craniofacial defects after tumor resection and frontal osteoradionecrosis.

JPRAS Open

March 2024

Centro Hospitalar de Vila Nova de Gaia/Espinho Serviço de Cirurgia Plástica Reconstrutiva, Craniomaxilofacial e Mão, Unidade de Microcirurgia. Centro Hospitalar Vila Nova de Gaia/Espinho, Rua Conceição Fernandes S/N, 4434-502 Vila Nova de Gaia, Portugal.

Skull osteoradionecrosis may happen after radiation therapy for head and neck cancer. Here in, the authors present a case of intracranial carcinoma with osteoradionecrosis and exposure of frontal bone with a large communication between nasal cavity and anterior fossa associated. The patient was successfully treated with resection of the tumor and reconstruction omentum free flap wrapped around autologous bone graft.

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Tuberculosis (TB) remains the most prevalent contagious disease worldwide and a significant cause of morbidity, ranking as the second most deadly disease globally. The transmission of the disease occurs through aerosols via the respiratory route, predominantly affecting pulmonary tissue. However, the pathogen can disseminate and infect any organ within the body.

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A 66-year-old man was admitted to the emergency department due to malaise, fatigue and anorexia for the last 2 weeks. He presented no fever, no respiratory or gastrointestinal symptoms. The patient had been previously diagnosed with Crohn's Disease (CD) (A2L1L4B1 of Montreal Classification) 10 years before, when he presented complaints of watery diarrhea and unexplained weight loss.

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Impact of the COVID-19 Pandemic on Global TAVR Activity: The COVID-TAVI Study.

JACC Cardiovasc Interv

February 2024

Department of Cardiology, Galway University Hospital, Galway, Ireland; School of Medicine, University of Galway, Galway, Ireland. Electronic address:

Article Synopsis
  • The COVID-19 pandemic led to significant treatment delays for patients needing transcatheter aortic valve replacement (TAVR), with a marked decrease in procedure volumes during the first two waves of the pandemic.
  • The study analyzed TAVR case data from 130 centers in 61 countries, finding a 15% drop in cases during the first wave and 7% in the second, particularly affecting regions like Africa, Central-South America, and Asia.
  • Factors such as hospital type (private vs public), urban vs rural location, low procedure volumes, a country's socioeconomic status, and stringent public health measures contributed to these reductions, highlighting the need for improved public health policies for future health crises.
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Left-Ventricular Unloading With Impella During Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis.

Crit Care Med

March 2024

Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charité, Campus Benjamin Franklin, Berlin, Germany.

Objectives: Extracorporeal cardiopulmonary resuscitation (ECPR) is the implementation of venoarterial extracorporeal membrane oxygenation (VA-ECMO) during refractory cardiac arrest. The role of left-ventricular (LV) unloading with Impella in addition to VA-ECMO ("ECMELLA") remains unclear during ECPR. This is the first systematic review and meta-analysis to characterize patients with ECPR receiving LV unloading and to compare in-hospital mortality between ECMELLA and VA-ECMO during ECPR.

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Introduction: Immune-mediated necrotizing myopathy (IMNM) is characterized by acute or subacute, severe proximal muscle weakness and myofiber necrosis with minimal inflammatory cell infiltrate observed on muscle biopsy. On the other hand, sarcoidosis is characterised by the presence of non-caseating granulomas that can develop in several organs.

Case Report: We present the unique case of a 49-year-old woman, with no previous medical history, who had a rare concomitant occurrence of IMNM and pulmonary sarcoidosis.

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The endovascular clip system device, eCLIPs (eVasc, Vancouver, British Columbia, Canada), was introduced almost a decade ago for the treatment of wide-neck bifurcation aneurysms,1-3 which represent a challenge for both endovascular and surgical approaches. Several techniques and devices (intrasaccular or intra-arterial) have been introduced and are currently available in order to improve the technical and clinical outcomes of aneurysm embolization. Flow diversion and flow disruption have shown controversial results in this subtype of aneurysm.

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Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR-Preserved.

J Cachexia Sarcopenia Muscle

February 2024

Department of Cardiology (CVK) of German Heart Center Charité; Institute of Health Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin, Berlin, Germany.

Background: Frailty is a severe, common co-morbidity associated with heart failure (HF) with preserved ejection fraction (HFpEF). The impact of frailty on HFpEF outcomes may affect treatment choices in HFpEF. The impact of frailty on HFpEF patients and any impact on the clinical benefits of sodium glucose co-transporter 2 (SGLT2) inhibition in HFpEF have been described in only a limited number of trials.

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Subcentimetric papillary thyroid carcinoma (SPTC) (papillary thyroid carcinoma with less than 10 mm in size) usually presents an excellent prognosis, with few aggressive reported cases. Given the globally increased incidence of SPTC, physicians are struggling with the need to identify prognostic factors to stratify SPTC. The aim was to compare clinicopathological variables and prognosis between clinically and incidentally diagnosed SPTC.

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