1,158 results match your criteria: "Centro Hospitalar de Lisboa Ocidental.[Affiliation]"

Biliary injury secondary to trauma is frequently associated with long-term complications. Liver transplantation is rarely indicated but might be the best therapeutic option in severe or intractable cases. We report the case of a 19-year-old male referred for liver transplantation due to biliary injury after abdominal trauma.

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Article Synopsis
  • The study aimed to translate and culturally adapt the modified Short Questionnaire to Assess Health-enhancing physical activity (mSQUASH) into Turkish, using a systematic approach that included expert reviews and patient feedback.
  • The translation process was straightforward, with minor issues resolved through expert consensus; the Turkish mSQUASH was found to be clear, relevant, and easy for patients to understand, though some sport examples were modified to better fit Turkish culture.
  • The final Turkish version of mSQUASH demonstrated good initial validity and usability, but further evaluation of its psychometric properties is necessary before it can be fully implemented in clinical settings.
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A man in his 60s presented to the emergency department with generalised abdominal pain and distention associated with the inability to pass stool or gas. The patient had undergone a laparoscopic partial right nephrectomy due to renal cell carcinoma a year ago. The workup diagnosis suggested an incarcerated incisional hernia.

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Aggressive angiomyxoma is a rare mesenchymal tumour, which usually appears in the pelvic region of women in their reproductive age. Although benign, it is a locally infiltrative tumour with frequent recurrence. We report a case of a pregnant woman in her 30s with a vulvar aggressive angiomyxoma which was initially misdiagnosed.

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Introduction And Objectives: Atrial fibrillation (AF) is the most common sustained arrhythmia, with significant burden for patients. Catheter ablation is safe and superior for symptom improvement. The purpose of this work was to assess how clinical practice compares with current scientific evidence and quality indicators for AF ablation.

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Objectives: The current European crisis in human resources in health has opened the debate about working conditions and fair wages. This is the case with Resident doctors, which have faced challenges throughout Europe. In Portugal, they account for about a third of the doctors in the Portuguese National Health Service.

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Challenges in Genetic Diagnosis of Mitochondrial Diseases: What Can Functional Genomics' Studies Do?

Endocr Metab Immune Disord Drug Targets

December 2023

Laboratory of Mitochondrial Biomedicine and Theranostics, CNC - Center for Neuroscience and Cell Biology, University of Coimbra.

Introduction: Mitochondrial oxidative phosphorylation (OXPHOS) diseases are challenging both from clinical and therapeutic perspectives. The advent of next-generation sequencing (NGS) boosted the discovery of new genetic defects affecting OXPHOS, with pathogenic variants identified in >350 genes to date [1]. However, in many patients, novel variants of unknown clinical significance are found.

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Caudal epidural block is a procedure that involves the injection of anesthetic agents through the sacral hiatus, commonly used for regional anesthesia. It is also valuable for chronic pain management in lumbosacral conditions, trauma, and palliative care. Ultrasound-guided caudal epidural blocks can be an alternative to fluoroscopy-guided techniques and have demonstrated a notably high success rate.

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Melasma results from the imbalance of the mechanisms that regulate skin pigmentation, causing the appearance of hyperpigmented patches. Treatment includes topical and oral agents, chemical peelings, microneedling, and laser therapy. The picosecond laser was developed to minimize pain and skin discoloration, which can sometimes be associated with laser treatments.

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Introduction: Upper limb spasticity can be responsible for several complications (e.g., pain, spasms, contractures, deformity, decreased or lost motor control), which can have a negative impact on functional independence and the quality of life of patients.

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Long-term follow-up of subthalamic nucleus deep brain stimulation in patients with Parkinson's disease: An analysis of survival and disability milestones.

Parkinsonism Relat Disord

January 2024

Neurology Department, Department of Neurosciences and Mental Health, Hospital Santa Maria, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal; Centro de Estudos Egas Moniz, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal; Instituto de Medicina Molecular João Lobo Antunes, Av. Prof. Egas Moniz, 1649-028, Lisboa, Portugal.

Background: Data on the long-term survival and incidence of disability milestones after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD) is limited.

Objectives: To estimate mortality and assess the frequency/time-to-development of disability milestones (falls, freezing, hallucinations, dementia, and institutionalization) among PD patients post STN-DBS.

Methods: A longitudinal retrospective study of patients undergoing STN-DBS.

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Detection of infections by computerized capture of peaks in longitudinally measured C-reactive protein levels.

Biomark Med

August 2023

Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark and Center for Clinical Epidemiology, Odense University Hospital, Kløvervænget 30, Entrance 216, Ground Floor, Odense C, 5000, Denmark.

We developed four algorithms for the automatic capture of C-reactive protein (CRP) peaks in 296 adult patients with acute myeloid leukemia who had bloodstream infection (BSI) episodes, negative blood cultures (BCs) or possible infections where no BCs were performed. The algorithms detected CRP peaks for 418-446 of the 586 documented BSI episodes (71.3-76.

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Introduction And Objectives: Concerns surrounding the consequences of ionizing radiation (IR) have increased in interventional cardiology (IC). Despite this, the ever-growing complexity of diseases as well as procedures can lead to greater exposure to radiation. The aim of this survey, led by Portuguese Association of Interventional Cardiology (APIC), was to evaluate the level of awareness and current practices on IR protection among its members.

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Non-invasive ventilation for cardiogenic shock associated respiratory failure - Striking the perfect balance between risk and benefit.

Rev Port Cardiol

May 2024

Serviço de Cardiologia, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal; NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal. Electronic address:

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Article Synopsis
  • Primary hepatic lymphoma (PHL) is a rare form of cancer affecting the liver, with a case study detailing a 30-year-old male exhibiting symptoms like fever, weight loss, and hepatomegaly; he was ultimately diagnosed with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) after a liver biopsy.
  • The patient underwent chemotherapy and achieved complete remission after a year and a half, highlighting that NLPHL is most common in men aged 30-50 and often presents with nonspecific symptoms that can mimic other illnesses.
  • The case emphasizes the complexity of diagnosing PHL, as common symptoms can overlap with infectious or autoimmune conditions, often delaying crucial treatment for malignancies.
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Portuguese Heart Failure Prevalence Observational Study (PORTHOS) rationale and design - A population-based study.

Rev Port Cardiol

December 2023

Pedro Hispano Hospital - ULS Matosinhos, Matosinhos, Portugal; Cardiology Department, Faculty of Medicine, University of Porto, Oporto, Portugal; RISE- Health Research Network, Faculty of Medicine, University of Porto, Oporto, Portugal.

Introduction And Objectives: Current epidemiological data on heart failure (HF) in Portugal derives from studies conducted two decades ago. The main aim of this study is to determine HF prevalence in the Portuguese population. Using current standards, this manuscript aims to describe the methodology and research protocol applied.

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Magnesium and vitamin D play important roles in most cells of the body. These nutrients act in a coordinated fashion to maintain physiologic functions of various organs, and their abnormal balance could adversely affect these functions. Therefore, deficient states of both nutrients may lead to several chronic medical conditions and increased cardiovascular and all-cause mortality.

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A male patient in his 20s with a medical history of common variable immunodeficiency disorder, non-compliant with therapy, presented to the emergency department with respiratory distress and severe hypoxaemia. Chest radiography demonstrated extensive bilateral infiltrates and an increased cardiothoracic ratio. urine antigen test was positive.

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Documentation and classification of hospital pharmacist interventions: A scoping review.

Br J Clin Pharmacol

March 2024

iMed.ULisboa and Departamento de Farmácia, Farmacologia e Tecnologias de Saúde, Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal.

The practice of documenting pharmacist interventions (PIs) has been endorsed by many hospital pharmacists' societies and organizations worldwide. Current systems for recording PIs have been developed to generate data on better patient and healthcare outcomes, but harmonization and transferability are apparently minimal. The present work aims to provide a descriptive and comprehensive overview of the currently utilized PI documentation and classification tools contributing to increased evidence systematization.

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Simultaneous Neuro-Ophthalmic Presentation and Progression of Idiopathic Intracranial Hypertension and Multiple Sclerosis.

J Neuroophthalmol

December 2024

Neurology Department (SPM, AFJ, AIM, SRB, JML), Coimbra University Hospital Centre, Coimbra, Portugal; Neurology Department (AFS-P), Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal; Neurorradiology Unit (DJP), Imaging Department, Coimbra University Hospital Centre, Coimbra, Portugal; Ophthalmology Department (PLF), Coimbra University Hospital Centre, Coimbra, Portugal; and Faculty of Medicine (AIM, SRB, JML), Coimbra University, Coimbra, Portugal.

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