11 results match your criteria: "Centro Hospitalar Lisboa Ocidental - Lisbon[Affiliation]"
A clinical guide to assess the immune response to sepsis: from bench to bedside.
Crit Care Sci
December 2024
Intensive Care Unit 4, Department of Intensive Care, Hospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental - Lisbon, Portugal.
Advancing insights in critical COVID-19: unraveling lymphopenia through propensity score matching - Findings from the Multicenter LYMPH-COVID Study.
Crit Care Sci
October 2024
Intensive Care Unit 4, Department of Intensive Care, Hospital São Francisco Xavier, Centro Hospitalar Lisboa Ocidental - Lisbon, Portugal.
Article Synopsis
- This study looked at how low levels of a type of white blood cell (called lymphocytes) in COVID-19 patients can affect their health outcomes.
- It included 912 adult patients in intensive care units in Portugal and Brazil to see how many had low lymphocyte counts and how it impacted their condition.
- The findings showed that patients with low lymphocyte counts were much sicker, needed more medical help, and had a higher chance of dying from the illness compared to those with normal levels.
Article Synopsis
- Researchers developed a 9-point score to predict positive outcomes for patients undergoing endovascular therapy (EVT) in late-presenting strokes (6-24 hours after last known well), based on a multinational study involving over 3,200 patients.
- The score takes into account factors like age, early CT changes, and stroke severity, with higher scores indicating a better chance of functional recovery at 90 days compared to those receiving only medical management.
- Validation of the score showed it is a useful tool for estimating EVT outcomes, particularly benefiting patients with lower to midrange scores in terms of good functional results and independence.
Background: Blood biomarkers are a potential tool for early stroke diagnosis. We aimed to perform a pilot and exploratory study on untargeted blood biomarkers in patients with suspected stroke by using mass spectrometry analysis.
Methods And Results: This was a prospective observational study of consecutive patients with suspected stroke admitted within 6 hours of last being seen well.
Handicap as a Measure of Perceived-Health Status in Parkinson's Disease.
Mov Disord Clin Pract
August 2023
CNS - Campus Neurológico Torres Vedras Portugal.
Background: Handicap is a patient-centered measure of health status that encompasses the impact of social and physical environment on daily living, having been assessed in advanced and late-stage Parkinson's Disease (PD).
Objective: To characterize the handicap of a broader sample of patients.
Methods: A cross-sectional study of 405 PD patients during the MDS-UPDRS Portuguese validation study, using the MDS-UPDRS, Unified Dyskinesias Rating Scale, Nonmotor symptoms questionnaire, PDQ-8 and EQ-5D-3L.
Article Synopsis
- - Wunderlich syndrome is a serious condition characterized by spontaneous kidney rupture and bleeding without obvious trauma, which can be life-threatening.
- - Apixaban, a medication used to prevent blood clots in patients with atrial fibrillation, has been linked to cases of solid organ rupture, though no prior instances of it causing Wunderlich syndrome had been documented.
- - This report discusses an unusual case of Wunderlich syndrome related to apixaban while highlighting the challenges doctors face when treating bleeding patients on anticoagulants.
A Curious Case of Dysphagia Due to Osteophytes.
Acta Med Port
March 2022
Departamento de Medicina Interna. Hospital de São Francisco Xavier. Centro Hospitalar Lisboa Ocidental. Lisboa. NOVA Medical School, Faculdade de Ciências Médicas. Universidade Nova de Lisboa. Lisbon. Portugal.
Epilepsy in tuberous sclerosis complex: Findings from the TOSCA Study.
Epilepsia Open
March 2019
Cardiology Clinical Academic Group, Molecular and Clinical Sciences Research Centre St Georges University of London London UK.
Article Synopsis
- The TuberOus SClerosis registry (TOSCA) aims to gather and present baseline data on patients with tuberous sclerosis complex (TSC), focusing on the prevalence and types of epilepsy associated with the condition.
- A comprehensive collection of patient data from multiple countries revealed that 83.6% of patients reported having epilepsy, with infantile spasms and focal seizures being the most common types, often diagnosed early in life.
- The findings highlight the importance of genetic factors in predicting the onset of seizures and the effectiveness of GABAergic drugs in treating epilepsy, suggesting better seizure control may correlate with a lower incidence of intellectual disabilities.
Radiofrequency for Treatment of Refractory Epistaxis in Hereditary Hemorrhagic Telangiectasia.
Acta Med Port
January 2018
Hereditary hemorrhagic telangiectasia is a rare multi-systemic autosomal dominant disorder characterized by dysplasia of the vascular connective tissue and recurrent bleeding tendency. Epistaxis is the most common and earliest symptom. It is usually mild to moderate, however, in some patients it can be severe with significant interference in quality of life.
View Article and Find Full Text PDFPancreatic Metastases as the Initial Manifestation of a Neuroendocrine Carcinoma of the Uterine Cervix.
Pancreas
February 2018
Department of Gastroenterology Centro Hospitalar Lisboa Ocidental Lisbon, Portugal Department of Radiology Centro Hospitalar Lisboa Ocidental Lisbon, Portugal Department of Gastroenterology Centro Hospitalar Lisboa Ocidental Lisbon, Portugal.
Cushing's syndrome due to ectopic ACTH production by a nasal paraganglioma.
Endocrinol Diabetes Metab Case Rep
March 2014
Department of Endocrinology Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental Lisbon Portugal.
Unlabelled: Ectopic secretion of ACTH is an infrequent cause of Cushing's syndrome. We report a case of ectopic ACTH syndrome caused by a nasal paraganglioma, a 68-year-old female with clinical features of Cushing's syndrome, serious hypokalaemia and a right paranasal sinus' lesion. Cranial magnetic resonance image showed a 46-mm mass on the right paranasal sinuses.
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