223 results match your criteria: "Centre of Mental Health[Affiliation]"

Background/objective: Behavioural Parent Training (BPT) is an evidence-based psychosocial intervention for attention-deficit/hyperactivity disorder (ADHD) in children. The use of online technologies significantly increases the accessibility of these interventions. This study aimed to assess the relative efficacy of face-to-face and online training in the use of parenting strategies taught.

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Introduction: Behavioral inhibition is a temperamental factor that increases the risk of internalizing disorders. Therefore, the identification of highly inhibited children is of great importance. However, informant discrepancies make this process difficult.

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Targeting sleep physiology to modulate glymphatic brain clearance.

Physiology (Bethesda)

November 2024

Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behavior, Nijmegen, Netherlands.

Article Synopsis
  • Sleep is crucial for removing neurotoxic substances like amyloid-β from the brain, and poor sleep can lead to neurotoxins building up, risking neuron death and increasing the chances of neurodegenerative diseases like Alzheimer's and Parkinson's.
  • There is a two-way relationship between sleep issues and neurodegeneration, indicating that sleep impairment may start affecting brain health long before symptoms show up.
  • The review discusses methods to enhance sleep's restorative functions through sensory, transcranial, pharmacological, and behavioral interventions aimed at boosting brain clearance and preventing cognitive decline.
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Unlabelled: Around the world, family caregivers are an important source of support for people with intellectual disability (ID) and for those with severe mental disorder (SMD), although the level of support can be influenced by the culture and government healthcare systems in each country. However, there is little evidence about the mental health and coping mechanisms of these caregivers in low-income countries. To address this need, we aimed to elicit whether there are potential links between coping style, mental health, and perceived burden experienced by this group, using a sample from a central Asian upper middle-income country.

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One-year ecological momentary assessment of alcohol use, mood, and stress among individuals with alcohol use disorder during SARS-CoV-2 pandemics: a gender-specific reflection.

Eur Arch Psychiatry Clin Neurosci

November 2024

Department of Clinical Psychology, Medical Faculty Mannheim, Central Institute of Mental Health (CIMH), University of Heidelberg, 68159, Mannheim, Baden-Wuerttemberg, Germany.

Alcohol consumption (AC) is a leading risk factor for death, morbidity, and disability worldwide. Gender-specific differences in AC and its moderators, which may serve as markers for preventing severe alcohol use disorders (AUD), showed inconsistent results. Additionally, the impact of COVID-19-related lockdowns on these differences remains unclear.

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Decrease in decision noise from adolescence into adulthood mediates an increase in more sophisticated choice behaviors and performance gain.

PLoS Biol

November 2024

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Centre of Mental Health, University of Würzburg, Würzburg, Germany.

Learning and decision-making undergo substantial developmental changes, with adolescence being a particular vulnerable window of opportunity. In adolescents, developmental changes in specific choice behaviors have been observed (e.g.

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Claudin-5 and occludin levels in patients with psychiatric disorders - A systematic review.

Brain Behav Immun

January 2025

Department of Psychiatry, University of Toronto, Toronto, Canada; Centre for Addiction and Mental Health, Toronto, Canada; Poul Hansen Family Centre for Depression, Centre of Mental Health, University Health Network, Toronto, Canada. Electronic address:

Background: Recent research has underscored the critical role of blood-brain barrier (BBB) integrity in psychiatric disorders, highlighting disruptions in tight junction (TJ) proteins, specifically claudin-5 and occludin. These proteins are pivotal in maintaining the BBB's selective permeability, which is essential forbrain homeostasis. Altered levels of the TJ proteins have been observed in various psychiatric conditions, suggesting potential as biomarkers for the pathophysiology of these disorders.

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Background: Bernstein's heuristic model of personal strengths describes 16 positive attributes of the healthy adult self, grouped into four higher-order factors: self-directedness (identity, self-reflection, self-confidence, self-assertion, imagination/creativity), self-regulation (emotional balance, resilience, self-control, self-care, reality testing), connection (empathy, compassion, humour, responsibility), and transcendence (gratitude and wisdom). The study aimed to explore the factorial validity of Bernstein's Strengths Scale developed for the assessment of these constructs. Furthermore, we explored the association of strengths with attention-deficit hyperactivity (ADHD) symptoms and mental health in a nonclinical sample using a network approach.

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"A way to liberate myself": A qualitative study of perceived benefits and risks of chemsex among gay, bisexual, and other men who have sex with men in Almaty, Kazakhstan.

Drug Alcohol Depend

November 2024

TUM School of Social Sciences and Technology, Technical University of Munich, Munich, Germany; Department of Social Policy and Intervention, University of Oxford, Oxford, UK.

Background: In Kazakhstan, the HIV epidemic has a significant impact on marginalized groups such as gay, bisexual and other men who have sex with men (GBMSM), exacerbated by homophobic attitudes (in society) and (resulting) minority stress. This stress often leads to coping behaviors such as chemsex - the use of synthetic stimulants to enhance sexual experiences. Our study explores the motivations and perceived risks associated with chemsex among GBMSM in Almaty.

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A societal challenge with high public health relevance: ADHD in children and adolescents in Germany.

J Health Monit

September 2024

University Hospital Würzburg, Centre of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Würzburg, Germany.

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Background: Attention-deficit/hyperactivity disorder (ADHD) is associated with increased costs for the family, the health care system and the society. Previous cost-of-illness studies in Germany usually focused on prevalent ADHD. This study addressed the research gap on health care resource utilisation and costs of children and adolescents with incident ADHD diagnosis using nationwide claims data from the statutory health insurance DAK-Gesundheit.

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Background: The study examines the psychometric properties of the ADHD section of the semi-structured diagnostic interview ILF-EXTERNAL, which was conducted online via video chat.

Methods: As part of the INTEGRATE-ADHD research project, 202 children and adolescents (age = 12.87 years, = 3.

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ADHD in children and adolescents: Guideline-based online assessment in the consortium project INTEGRATE-ADHD.

J Health Monit

September 2024

University Hospital Würzburg, Centre of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Würzburg, Germany.

Background: The consortium project INTEGRATE-ADHD compared administrative data on the presence of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents with the results of a parent survey and a comprehensive clinical assessment based on the S3 guideline of the Association of the Scientific Medical Societies in Germany (AWMF). Due to the COVID-19 pandemic, the clinical assessment was carried out online.

Methods: The article describes how a guideline-based clinical assessment of ADHD can be implemented in an online setting.

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Background: This article examines discrepancies in the frequency of diagnoses of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents in Germany using information on health care utilisation from both administrative and parent-reported survey data linked at person level.

Methods: 5,461 parents of 0- to 17-year-olds insured with DAK-Gesundheit in 2020 and being registered with a confirmed administrative ADHD diagnosis (ICD-10 F90.0-9) in at least one quarter in 2020 (M1Q criterion) were surveyed online on their child's ADHD diagnosis, utilisation of specialist care and therapeutic service providers.

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Article Synopsis
  • The INTEGRATE-ADHD project linked ADHD diagnosis data from parents and administration for the first time in Germany, analyzing discrepancies based on sociodemographic factors.
  • A survey of 5,461 children revealed that 71.6% of parents confirmed their child's ADHD diagnosis, with lower reporting rates among girls, younger children, those with migration backgrounds, and children from nuclear families.
  • About one-third of parents did not report their child's ADHD diagnosis, indicating variations in reporting influenced by sociodemographic characteristics, which should be considered in future data interpretations.
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Background: The health-related quality of life (HRQoL) of individuals living with Attention-deficit/hyperactivity disorder (ADHD) is known to be impaired. Identifying factors that influence HRQoL can provide important information for the development of prevention and intervention programmes for affected children and adolescents. The aim of the present study was to investigate health care-related and psychosocial risk and protective factors for HRQoL in children and adolescents with an administrative ADHD diagnosis.

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Introduction: Early recognition and indicated prevention is a promising approach to decrease the incidence of Major depressive episodes (MDE), targeting the patients during their clinical high-risk state of MDE (CHR-D). The identification of a set of stressors at the CHR-D increases the success of indicated prevention with personalized early interventions. The study evaluated stressors in the early phase of depression, developed on the basis of a patient survey on stressors.

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Testing a Motor Score Based on PANSS Ratings: A Proxy for Comprehensive Motor Assessment.

Schizophr Bull

September 2024

Translational Research Center, University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Article Synopsis
  • - Abnormal psychomotor behavior is a key symptom of schizophrenia, and the study explores whether certain items from the Positive and Negative Syndrome Scale (PANSS) can effectively measure motor abnormalities.
  • - By analyzing data from two clinical trials, researchers found a significant correlation between the PANSS motor score and various established motor rating scales, with a specific cutoff for differentiating patient motor behavior.
  • - The results suggest that the PANSS motor score could serve as a useful proxy for assessing hypokinetic motor abnormalities, potentially aiding in research for interventions targeting these issues in individuals with psychosis.
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The Strengths and Weaknesses of ADHD Symptoms and Normal Behaviour Scale (SWAN) measures the full spectrum of attention and activity symptoms, not just the negative end of the distribution. Previous studies revealed strong psychometric properties of the parent and teacher report versions; however, there is little research on the new self-report form of the SWAN. Therefore, our research aimed to explore the psychometric characteristics of the SWAN self-report.

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Neurocomputational Mechanisms Underlying Differential Reinforcement Learning From Wins and Losses in Obesity With and Without Binge Eating.

Biol Psychiatry Cogn Neurosci Neuroimaging

December 2024

Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Centre of Mental Health, University of Würzburg, Würzburg, Germany; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Department of Psychiatry and Psychotherapy, Technical University of Dresden, Dresden, Germany.

Background: Binge-eating disorder (BED) is thought of as a disorder of cognitive control, but evidence regarding its neurocognitive mechanisms is inconclusive. Key limitations of previous research include a lack of consistent separation between effects of BED and obesity and a disregard for self-report evidence suggesting that neurocognitive alterations may emerge primarily in loss- or harm-avoidance contexts.

Methods: To address these gaps, in this longitudinal study we investigated behavioral flexibility and its underlying neurocomputational processes in reward-seeking and loss-avoidance contexts.

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There has been a plethora of studies on urbanization and older adults, and more recent ones on how older adults adapt to this process with their cognitive competence. Yet it has been unclear about the relationship between them, like how the level and rate of urbanization affect the cognitive function among older adults. This study sourced, formed, and analyzed a set of geospatial big datasets from different sources, such as the Chinese Longitudinal Healthy Longevity Survey (CLHLS) data, and the NPP/VIIRS nighttime light (NTL) data.

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An important correlate of mental health problems is mentalizing capacity, which appears to be particularly influential during adolescence. However, quality of life has not been studied in relation to mentalizing capacity among adolescents. This study aimed to translate the Reflective Function Questionnaire for Youth (RFQY) into Hungarian, present its psychometric properties, and assess its relationship with demographic characteristics, psychopathology and quality of life.

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Objective: Eating disorders (ED) have recently been studied from a network approach, conceptualising them as a complex system of interconnected variables, while highlighting the role of non-ED symptoms and personality dimensions. This study aims to explore the connections between personality and ED symptoms, identify central nodes, and compare the EDs network to a healthy control network.

Methods: We employed network analysis to examine the personality-ED symptom connections in 329 individuals with an ED diagnosis and 192 healthy controls.

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