34 results match your criteria: "Centre national de reference des Lymphœdemes Primaires[Affiliation]"

[Update of indications and techniques for the management of lymphedema after breast cancer surgery].

Gynecol Obstet Fertil Senol

March 2024

Unité de lymphologie, Centre de référence des lymphœdèmes primaires, membre de la filière FAVA-Multi et du Réseau européen VASCERN, hôpital de Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

Objectives: Upper limb lymphedema secondary to breast cancer treatment is the leading cause of lymphedema in France. Despite improved surgical practices and de-escalation of radiotherapy, the risk of lymphedema after breast cancer still affects 5-20% of patients, with this variation depending on the measurement method used and the population studied. Lymphedema has a negative impact on quality of life and body image, and their possible occurrence remains a major concern for all women treated for breast cancer.

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Introduction: Yellow nail syndrome (YNS), a very rare disorder of unknown etiology, is characterized by a triad associating yellow nails, respiratory manifestations, and lymphedema. YNS treatment remains non-codified.

Method: This retrospective study was conducted from January 2008 to December 2022 in a single tertiary department exclusively dedicated to lymphatic diseases.

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[Pretibial myxedema after Graves' disease: A differential diagnosis of lymphedema].

Rev Med Interne

December 2023

Unité de lymphologie, site constitutif du centre national de référence des lymphœdèmes primaires, hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

Article Synopsis
  • Pretibial myxedema is an uncommon symptom of Graves' disease that can resemble lower limb lymphedema, complicating diagnosis.* -
  • The study includes three cases of pretibial myxedema in patients with a history of Graves' disease, where misdiagnosis of lymphedema was suspected due to specific leg symptoms.* -
  • Proper diagnosis involves evaluating the patient's medical history, particularly regarding Graves' disease, and addressing lifestyle factors like smoking that could worsen the condition.*
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Prevalence of Chronic Pain Among People with Dementia: A Nationwide Study Using French Administrative Data.

Am J Geriatr Psychiatry

December 2023

Service de Pharmacologie médicale (NK, NB, ST, NA, CB, CC), Centres Addictovigilance et Pharmacovigilance, Centre d'Evaluation et de Traitement de la Douleur, Université Clermont Auvergne, CHU Clermont-Ferrand, INSERM, NEURO-DOL, F-63000 Clermont-Ferrand, France; Université Clermont Auvergne (NK, NA, CB, CC), Institut Analgesia, Clermont-Ferrand, France; Observatoire Français des Médicaments Antalgiques (OFMA) (NA, CB, CC), Université Clermont Auvergne, Clermont-Ferrand, France.

Objective: Alzheimer's disease or Related Dementia (ADRD) is known to disturb pain perception and reduce the ability to report it, resulting in underestimation by practitioners and sub-optimal medical management. The aim of this study was to estimate the prevalence of all types of CP among people with ADRD.

Design: Nationwide cross-sectional study.

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[Increased trunk volume].

Rev Med Interne

October 2023

Unité de lymphologie, Centre national de référence des Lymphœdèmes Primaires, hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

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Genital Lymphedema after Cancer Treatment: A Narrative Review.

Cancers (Basel)

November 2022

Department of Lymphology, Centre National de Référence des Maladies Vasculaires Rares (Lymphoedèmes Primaires), Hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France.

Genital lymphedema may affect males and females after cancer treatment (gynecological, such as cervical, uterine or ovarian, melanoma, prostate, anus…). It is frequently associated with lower limb lymphedema, and is responsible for discomfort, cosmetic disfigurement and functional disturbances. Impacts on body image, sexual function and quality of life are major, and difficult to explore because cancer treatment itself and lymphedema are so closely interwoven.

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MEDICAL MANAGEMENT OF LIMB LYMPHEDEMA. Lymphedema results from impaired lymphatic transport then tissue modifications (adipose deposition, thickening skin) leading to an increased limb volume. Lymphedema management is based on complete decongestive physiotherapy (multilayer low stretch bandage, manual lymph drainage, skin care, exercises).

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[Puffy hand syndrome: A little-known diagnosis].

Rev Med Interne

October 2020

Unité de Lymphologie, Site constitutif du Centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), Hôpital Cognacq-Jay, 15 rue Eugène Millon, 75015 Paris, France. Electronic address:

Introduction: Puffy hand syndrome is a rare complication of intravenous drug addiction. Diagnosis is based on the patient's history and clinical examination.

Observations: A woman and two men, aged 42, 39 and 36 years old, are described.

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Sport activities and exercise in individuals with lymphedema: a French national survey on practices and fears.

Eur J Dermatol

February 2020

Department of Dermatology and Reference Center for Rare Diseases and Vascular Malformations (MAGEC), CHRU Tours, 37044 Tours Cedex 9, France, Universities of Tours and Nantes, INSERM 1246 - SPHERE, 37000 Tours, France.

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[Lower limb lymphedema: A rare manifestation of spondyloarthropathy].

Rev Med Interne

December 2019

Unité de Lymphologie, site constitutif du Centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

Introduction: Spondyloarthritis include articular (axial, peripheral or enthesitic) and extra-articular manifestations. We reported three cases of limb lymphedema associated with a spondyloarthritis.

Case Reports: We report on two men and one female aged of 75, 52 and 39 years, respectively.

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[A large thigh of unusual cause].

Rev Med Interne

February 2020

Unité de lymphologie, site constitutif du centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

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Introduction: In France, breast cancer is the most frequent cancer in women. Lymphedema, the main complication, is poorly known. The objective of this study was to assess the state of knowledge of upper limb lymphedema (risk factors, complications, treatment) after treatment of breast cancer among general practitioners from the Haute-Normandie and ÃŽle-de-France regions.

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[Lymphedema in patients treated with sirolimus: 15 cases].

Rev Med Interne

March 2019

Unité de lymphologie, site constitutif du Centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

Background: Sirolimus is a mammalian target of rapamycin (mTOR) inhibitor used after organ transplantation and to treat vascular malformations. Among its adverse effects, limb lymphedema has been described.

Objective: The aim of this study was to analyze the clinical features, lymphoscintigraphy and lymphedema outcome in patients treated with sirolimus.

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Lymphoedema, primary and secondary after cancer treatment, is a chronic condition which has a significant impact on patients' quality of life. Therapeutic education plays an important role in the initial care and in the follow-up of these conditions.

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[Primary lymphedema in childhood].

Arch Pediatr

August 2017

Service de dermatologie, hôpital Necker, AP-HP, 149, rue de Sèvres, 75012 Paris, France.

Lymphedema results from impaired lymphatic transport with increased limb volume and is divided into primary and secondary forms. In children, primary lymphedema is the most frequent, with a sporadic, rarely familial form or associated with complex malformative or genetic disorders. Diagnosis of lymphedema is mainly clinical and lymphoscintigraphy is useful to assess the lymphatic function of both limbs precisely.

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Lymphedema, a chronic debilitating disease, is not always easily diagnosed. A total of 254 new patients ((217 women, 37 men), median (Q1-Q3) age 61 (46-72) years) were referred for suspected limb lymphedema to an exclusively lymphedema-dedicated department for a first consultation (January - March 2015) were included; among 118 with upper limb involvement, 100 (84.7%) were diagnosed with post-breast cancer therapy and four with primary lymphedemas; among 136 with lower limb involvement, 31 (22.

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Yellow nail syndrome: a review.

Orphanet J Rare Dis

February 2017

Nail Disease Centre, 42, rue des Serbes, 06400, Cannes, France.

Yellow nail syndrome (YNS; OMIM 153300, ORPHA662) is a very rare disorder that almost always occurs after 50 years of age but a juvenile or familial form has also been observed. YNS is diagnosed based on a triad associating yellow nail discoloration, pulmonary manifestations (chronic cough, bronchiectasia, pleural effusion) and lower limb lymphedema. Chronic sinusitis is frequently associated with the triad.

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