3 results match your criteria: "Centre national de référence des Herpèsvirus (NRCHV)[Affiliation]"

Article Synopsis
  • The study aimed to evaluate whether the QuantiFERON®-CMV test could predict CMV recurrence in heart transplant recipients and improve the management of secondary prophylaxis duration.
  • Out of 15 patients with CMV infection, 33% experienced recurrence, but the QuantiFERON®-CMV test did not significantly correlate with recurrence rates or the length of prophylaxis.
  • The findings suggest that the QuantiFERON®-CMV assay may not be effective for predicting CMV recurrence in this patient group, indicating a need for alternative tests and treatment strategies, such as using everolimus in immunosuppressive regimens.
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Background: Fecal Microbiota Transplantation (FMT) has become the preferred treatment for recurrent Clostridioides difficile Infections (CDI). However, donor screening is a complex process that varies between countries. The primary objective of screening is to prevent the transfer of potential pathogens from the donor to the recipient via feces.

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[The terminase complex, a relevant target for the treatment of HCMV infection].

Med Sci (Paris)

April 2020

Univ. Limoges, Inserm, CHU Limoges, RESINFIT, U1092, 87000 Limoges, France - CHU Limoges, Laboratoire de bactériologie-virologie-hygiène, Centre national de référence des Herpèsvirus (NRCHV), 87000 Limoges, France.

Human cytomegalovirus (HCMV) is an important ubiquitous opportunistic pathogen that belongs to the betaherpesviridae. Primary HCMV infection is generally asymptomatic in immunocompetent individuals. In contrast, HCMV infection causes serious disease in immunocompromised patients and is the leading cause of congenital viral infection.

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