[Impact of nutritional factors during and after cancer].

Nutritional factors (diet, weight, alcohol, physical activity) are identified as factors having an impact on the onset of several cancer sites. Less abundant scientific data also underline their impact on the tumor progression. A review of the scientific literature was carried out by a group of experts established by the French National Cancer Institute (INCa) to better document the influence of nutritional factors during and after cancer on outcomes such as overall mortality, cancer specific mortality, recurrence, second primary cancers and quality of life.

[Free circulating DNA as a tool for lung cancer patients management].

Free circulating DNA (cfDNA) has been known for several decades. These small DNA fragments are released into the circulation from nucleated cells through necrosis, apoptosis and/or active secretion. These genomic fragments are mainly constitutional (nucleated blood cell DNA), but in patients with cancer, a fraction comes from tumor cells.

[Alcohol and cancer].

Regular consumption of alcoholic beverages increases the risk of cancer in the upper aero-digestive tract and in the liver. There is a dose-response relationship and the effects are combined with those of tobacco, according to a multiplicative model. The biologic mechanisms are unclear.

[Smoking and social class in France 1974-1991].

We examined trends in cigarette smoking behaviour in France from 1974 to 1991 separately for men and women as well as according to social class indicators. Overall, cigarette smoking prevalence has declined among men but has increased among women over the 18-year period which was taken into consideration. Analysis by social class groupings shows, among men, that the decrease is greater among higher level executives, professionals and academics and occurred as early as 1983.