and evaluation of antifungal combinations against azole-resistant isolates.

Azole resistance in (Af) has become a widespread threat and a major concern for optimal management of patients with invasive aspergillosis (IA). Combination of echinocandins with azoles is an attractive alternative option for the treatment of IA due to azole-resistant Af strains. The aim of this study was to evaluate the and combination of caspofungin (CAS) with either voriconazole (VRZ) or posaconazole (PSZ).

In Vivo Efficacy of Voriconazole in a Model of Invasive Infection Due to Azole-Susceptible or Resistant Isolates.

is an environmental filamentous fungus responsible for life-threatening infections in humans and animals. Azoles are the first-line treatment for aspergillosis, but in recent years, the emergence of azole resistance in has changed treatment recommendations. The objective of this study was to evaluate the efficacy of voriconazole (VRZ) in a model of invasive infection due to azole-susceptible or azole-resistant isolates.

[Ocular manifestations of Behçet's disease].

Introduction: Behçet's disease is a systemic inflammatory disease. Ocular involvement is an important diagnostic criterion, and this disease may be associated with severe visual loss.

Purpose: The goal of this study was to specify the epidemiological, clinical and therapeutic features of ocular involvement in patients with Behçet's disease and to identify risk factors for poor visual outcomes.

for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review.

The treatment of invasive fungal infections remains challenging and the emergence of new fungal pathogens as well as the development of resistance to the main antifungal drugs highlight the need for novel therapeutic strategies. Although in vitro antifungal susceptibility testing has come of age, the proper evaluation of therapeutic efficacy of current or new antifungals is dependent on the use of animal models. Mammalian models, particularly using rodents, are the cornerstone for evaluation of antifungal efficacy, but are limited by increased costs and ethical considerations.

[Orbital cellulitis in children: Report of 60 cases].

Unlabelled: The goal of this study was to describe the epidemiological, etiological, clinical and therapeutic features and clinical course of orbital cellulitis in children, and to assess the risk factors for retroseptal involvement.

Methods: This was a retrospective study including 60 children (67 eyes) diagnosed with orbital cellulitis. Two groups were defined according to the clinical form: pre- or retroseptal.

[Panniculitis in patient undergoing treatment for dermatomyositis with methotrexate].

Panniculitis is a rare cutaneous manifestation of dermatomyositis (DM). The appearance of panniculitis during treatment with methotrexate (MTX) is exceptional and has only been described in 3 cases. We report a case of a 50-year-old woman suffering from DM since 1997 who was treated with corticosteroids showing favorable clinical and biological evolution.

[Intradiverticular tumors of the bladder: diagnostic and therapeutic problems: report of 32 cases].

Background: The transitional cell carcinoma within the bladder diverticular is a rare and poorly known entity.

Aim: To evaluate diagnostic and therapeutic approaches of transitional cell carcinoma within the bladder diverticular.

Methods: Thirty men and two women (median: 70 years; 44- 83 years) were included.

[Renal colic in pregnancy and lactation: diagnostic and therapeutic approaches].

Background: Renal colics due to urinary stones are also common in women of childbearing age whether pregnant or not.

Aim: Through a review of literature, we evaluated diagnostic and therapeutic approaches in renal colic in pregnancy and lactation.

Methods: Review of literature.

Rosai and Dorfman disease with pleural involvement: case report.

Sinus histiocytosis with massive lymphadenopathy (SHLM) disease is considered to be an indolent and self-limiting pathology. However, severe morbidity and mortality have been attributed to complications of SHLM. Lower respiratory tract involvement is rarely reported and is often unfavorable, and carries a particularly grave prognosis.