Performance of ParaHIT® HRP2-Based Rapid Diagnostic Test and Proportions of Plasmodium falciparum Histidine-Rich Protein 2/3 Gene Deletions in Togo.

In areas where malaria is endemic and microscopes are unavailable, rapid diagnostic tests (RDTs) are essential tools for early diagnosis and prompt and effective treatment. However, HRP2-based RDTs are threatened by the emergence of Plasmodium falciparum parasites that do not carry the pfhrp2 or pfhrp3 gene, leading to false-negative results. Therefore, the aim of this study was to evaluate the performance of the ParaHIT RDT together with the proportion of pfhrp2/3 gene-deleted P.

[Auricular and periauricular pathologies in the ENT department of Sylvanus Olympio Teaching Hospital in Lome (Togo)].

Objective: The aim of this study is to describe the epidemiological aspects, clinical features and principles of management of different types of auricular and peri-auricular pathologies.

Patients And Methods: This is a 5-year retrospective descriptive study (from May 1, 2018 to April 30, 2023) of the records of patients who consulted for a functional or cosmetic complaint relating to the auricle or periauricular region in the ENT and cervico-facial surgery department of the Centre hospitalier universitaire Sylvanus Olympio.

Results: A total of 159 cases over 5 years, i.

Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine and prevalence of molecular markers of anti-malarial drug resistance in children in Togo in 2021.

Background: Artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) are the currently recommended first- and second-line therapies for uncomplicated Plasmodium falciparum infections in Togo. This study assessed the efficacy of these combinations, the proportion of Day3-positive patients (D3 +), the proportion of molecular markers associated with P. falciparum resistance to anti-malarial drugs, and the variable performance of HRP2-based malaria rapid diagnostic tests (RDTs).

[Evaluation of the risk of obstructive sleep apnea in patients awaiting general anesthesia in Burkina Faso].

Introduction: General anaesthesia and surgery increase morbidity and mortality in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) who are not known to have OSAHS and therefore not treated before surgery. The objective of this study is to evaluate the risk of OSAHS using the STOP-BANG questionnaire (SBQ) in patients undergoing general anaesthesia in Burkina Faso.

Material And Method: This is a cross-sectional study concerning patients having received pre-anaesthetic consultation from 1st July 2020 to 30th June 2021.

Progress from morbidity control to elimination as a public health problem of schistosomiasis and the status of soil-transmitted helminth infection in Togo: a second impact assessment after ten rounds of mass drug administration.

Background: Due to the burden of schistosomiasis (SCH) and soil-transmitted helminths (STH), Togo Ministry of Health launched a program for Preventive Chemotherapy Neglected Tropical Diseases (PC-NTDs) in 2009, initiating integrated mass drug administration (MDA) the following year for the three PC-NTDs: SCH, STH and onchocerciasis. Significant reduction of infection across the country was noted in 2015 during the first impact assessment, following 5 years of high-coverage MDA implemented at the sub-district level for SCH and district level for STH. After another 5 years of effective MDA, a second survey was conducted in 2021 to re-evaluate the situation of SCH and STH.

[Necrotizing fasciitis of the posterior neck. A rare clinical form of head and neck cellulitis: a case report from Togo].

We report the case of a 75-year-old diabetic patient who presented with posterior cervical necrotizing fasciitis complicating cellulitis. Medical management in intensive care and surgical drainage were undertaken; sequential excision of the necrotic tissue left a large loss of substance of the nuchal region for which we opted for directed healing in the first instance. The definitive coverage of this loss of substance by locoregional rotation flap or by thin skin grafting was discussed.

Disclosure of HIV status and adherence to antiretroviral treatment in children and adolescents from Lomé and Abidjan.

Introduction: in Africa, the proportion of minors with AIDS is ever increasing and adherence to treatment protocols is still suboptimal. The study investigated the conditions of HIV status disclosure and adherence to treatment in patients < 19 in two West African cities.

Methods: in 2016, thirteen health professionals and four parents filled out questionnaires to identify problems and solutions relative to disclosure of HIV status and adherence to treatment in 208 children and adolescents seen at University Hospitals in Abidjan (Ivory Coast) and Lomé (Togo).

[HIV prevention among serodifferent couples: postures and difficulties in Lomé (Togo)].

Introduction: The protocol for the management of HIV-positive couples in Togo recommends the systematic use of condoms as the only means of preventing the sexual transmission of HIV. Nevertheless, the incidence of HIV in Togolese serodifferent couples remains high.

Purpose Of Research: The aim of the article is to identify barriers to compliance with official guidelines for the prevention of sexual transmission of HIV among serodifferent couples in Lomé.

[Measurement Of Umbilical cord diameter On Ultrasound: An Indicator Of Fetal growth].

Introduction: One of the main goals of routine antenatal care is to identify mal developing fetuses and fetal ultrasound biometry parameters are used for this purpose. The objective of this study was to establish the norms of umbilical cord diameter (UCD) and to investigate its relationship with estimated fetal weight (EFW) and other fetal biometry parameters.

Populations And Methods: This was a descriptive and analytical cross-sectional study with prospective data collection conducted in the radiology and medical imaging and gynaecological-obstetrics departments of Sokodé regional hospital.

Awareness and willingness to participate in clinical trials in Togo.

Context: Clinical Trials (CTs) are the key when it comes to informing clinical decision-making processes. There is a very low number of CTs conducted in Togo, and there is no study that assessed the willingness of Togolese to participate in CTs.

Aims: The aim of this study was to assess public awareness and willingness to participate in CTs in Togo.

[Trends of HIV and syphilis prevalence among pregnant women in antenatal clinics in Togo: Analysis of sentinel serosurveillance results between 2008 and 2016].

Introduction: The aim of our work was to analyse the trends of HIV infection and syphilis among pregnant women in prenatal consultation (PNC) in healthcare facilities in Togo.

Methods: This was an analytical retrospective study, covering the period from 2008 to 2016 and focusing on pregnant women aged 15 to 49 seen in PNC for the first time in maternal and child health services in Togo.

Results: During the study period, 41,536 pregnant women were registered in 2008, 2009, 2010, 2014 and 2016, respectively 8079, 8572, 8430, 7920 and 8535.

Medicinal plant use and adherence problems to TB treatment.

Good adherence is essential in the treatment of TB. The aim of this study was to describe medication consumption patterns and to assess factors associated with adherence to TB treatment among TB patients in Lomé, Togo. A cross-sectional study was conducted among TB patients in 10 health structures in Lomé from September 2019 to January 2020.

[Évaluation de la qualité de vie et description des facteurs associés, chez les patients en insuffisance cardiaque chronique vivant dans un pays d'Afrique de l'Ouest à faible revenu].

Objective: To assess the quality of life (QOL) and describe associated factors in patients with chronic heart failure (HF) living in a low-income population in West Africa.

Methods: This is was a cross-sectional study conducted from January 2017 to June 2018, in the department of cardiology of the University Teaching Hospital (CHU-Campus) in Lomé (Togo). Enrolled patients had stable chronic HF and have been hospitalized in the past 6 months; QOL was assessed using the Minnesota Living with Heart Failure questionnaire (MLHFQ).

[Distribution of dermatoses encountered in children seen in Dermatological Consultations in Lomé (Togo)].

Objective: The aim of this study was to establish the overview of current dermatosis in children in dermatological consultation in Lomé and to deduce the evolutionary trend of these dermatoses between 1992 and 2020.

Method: This was a retrospective descriptive study concerning patients aged 0 to 15 years seen in consultation in the public dermatological services of Lomé from January 1, 2010 to December 31, 2019. The reasons for consultation were reviewed and classified into groups of dermatosis (immunoallergic, infectious, inflammatory, tumoral …).

[Efficacy of highly active antiretroviral therapy alone in the treatment of diffuse lymphocytic infiltration syndrome in an ivorian patient living with HIV: a case report].

Objective: We report in this work the efficacy of highly active antiretrovirals (ARVs) alone in the treatment of diffuse infiltrative lymphocytosis syndrome (DILS) without the use of corticosteroids, which appears risky in patients living with HIV.

Observation: This is a 60-year-old HIV-positive patient, discovered during the etiological workup of renal failure, which revealed a non-nephrotic glomerular profile. The renal biopsy found an interstitial infiltrate of CD8 suggestive of DILS.

24-Month Clinical, Immuno-Virological Outcomes, and HIV Status Disclosure in Adolescents Living With Perinatally-Acquired HIV in the IeDEA-COHADO Cohort in Togo and Côte d'Ivoire, 2015-2017.

Adolescents living with perinatally-acquired HIV (APHIV) face challenges including HIV serostatus disclosure. We assessed their 24-month outcomes in relation to the disclosure of their own HIV serostatus. Nested within the International epidemiologic Database to Evaluate AIDS pediatric West African prospective cohort (IeDEA pWADA), the COHADO cohort included antiretroviral (ART)-treated APHIV aged 10-19 years, enrolled in HIV care before the age of 10 years, in Abidjan (Côte d'Ivoire) and Lomé (Togo) in 2015.

[Anemia in blood donors and criteria of hemoglobin level control at the national blood transfusion center (NBTC) of Lomé, Togo].

Introduction: The aim of this study was to evaluate the prevalence of anemia among blood donors at Lomé national blood transfusion center (NBTC) and to identify criteria for controlling hemoglobin level in blood donation candidates.

Methods: We determined the hemoglobin level using HemoCue® 201+. To identify the hemoglobin level control criteria, the judgment parameters were the proportion of anemic donors based on the number of blood donations in the last 12 months and the staining of the conjunctiva.

[Brown Sequard syndrome revealing a cervical pott's disease associated with a retropharyngeal abscess].

A 37-year-old patient was admitted for a left progressive left-hand hemiparesis associated with left C4-C5 neuralgia preceded by inflammatory neck pain for 04 months and dysphagia for 02 weeks. Magnetic resonance imaging showed C3-C5 spondylodiscitis lesions with epidural abscess and predominantly left lateralized compression of the spinal cord and retropharyngeal abscess. The patient was operated for incision and drainage of the retropharyngeal abscess through the oral cavity and Koch bacillus was demonstrated from the aspirate by molecular technique GeneXpert.

Predictors of three-month mortality among hospitalized older adults in Togo.

Background: Assessing hospital mortality and its predictors is important as some of these can be prevented through appropriate interventions. Few studies have reported hospital mortality data among older adults in sub-Saharan Africa. The objective of this study was to assess the mortality and associated factors among hospitalized older adults in Togo.

Duodenocolic fistula by nail ingestion in a child.

Unintentional foreign body ingestion is common among children. Normally, these ingested foreign bodies pass spontaneously. Only few of them may lead to complications such as fistula, which requires surgical intervention.

Severe snakebite envenomation revealed by an acute abdomen.

Acute abdomens are common conditions, with many aetiologies in developing countries. Abdominal bleeding due to snake envenomation is an extremely rare aetiology. A 11-year-old girl was admitted for acute abdominal pains.

[Spontaneous idiopathic pneumoperitoneum: about a case].

Pneumoperitoneum, in the majority of cases, is caused by a perforation of the gastrointestinal tract whose treatment is usually surgical. It rarely occurs spontaneously. This study reports an unusual presentation of pneumoperitoneum which has put the surgeon in a massive diagnostic and therapeutic dilemma.

[Ambulatory treatment of penile fracture at teaching hospital in Lomé].

Objectives: To study the feasibility of outpatient management of fractures of the penis and to identify factors that promote their occurrence.

Materials And Method: This were a prospective, monocentric study of patients who received emergency treatment for fractured penises. It took place from January 2016 to January 2019.

[Non-traumatic splenic rupture revealed by acute renal failure].

We report a case of rupture of spontaneous subcapsular splenic hematoma caused by toxic product and revealed by acute renal failure with intravascular hemolysis.