113 results match your criteria: "Centre hospitalier universitaire Mohammed VI[Affiliation]"

Article Synopsis
  • - Ovarian tumors in children are rare, occurring at a rate of 2.6 per 100,000, with symptoms often including abdominal pain and the need for thorough diagnostic evaluation using imaging like pelvic ultrasounds.
  • - A 15-year-old girl presented with a six-month history of an enlarging abdominal mass and negative tumor markers, leading to an ultrasound and MRI that revealed a large cystic mass occupying her abdomen and pelvis.
  • - She underwent laparoscopic surgery to remove the cyst, which involved draining 6 liters of fluid and preserving part of her left ovary; follow-up care is ongoing.
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Agenesis of the left pulmonary artery represents a rare malformation, accounting for a small fraction of all cases of congenital heart disease. It is characterized by the absence of the left pulmonary artery, which can lead to respiratory and cardiac complications. This anomaly can appear on a standard chest X-ray, but it must be confirmed by a chest CT scanner, which makes it possible to visualize the absence of the left pulmonary artery and the associated parenchymal anomalies.

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[Abdominal obstruction revealing colonic lymphoma: a case report].

Pan Afr Med J

September 2024

Service d'Hématologie et Greffe de Moelle, Centre Hospitalier Universitaire Mohammed VI, Faculté de Médecine et de Pharmacie, Université Cadi Ayyad, Marrakech, Maroc.

Colonic lymphoma is a rare malignant gastrointestinal tumor that can be revealed by an exceptional and serious complication: intestinal obstruction. Treatment is based on surgery and chemotherapy. We here report a case of diffuse colonic large B-cell lymphoma revealed by occlusion and diagnosed based on the examination of surgical specimen in a 64-year-old man who was in complete remission after six courses of R-CHOP.

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Portal cavernoma is a major cause of extrahepatic portal hypertension (EHPH) in children. It is a serious condition, due to the frequency and severity of digestive hemorrhages secondary to the rupture of esophageal varices (EV). Neonatal umbilical catheterization is a significant risk factor for the development of portal vein thrombosis (PVT) and portal hypertension.

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Article Synopsis
  • Extramedullary solitary plasmacytoma (SP) is a rare tumor, especially in the head and neck regions, as demonstrated in a case involving an 82-year-old man with nasal cavity SP.
  • The patient was found to have an advanced tumor unfit for surgery and initially received radiotherapy at a total dose of 50 Gy.
  • After nine months, the tumor recurred, leading to palliative chemotherapy with cyclophosphamide, dexamethasone, and thalidomide, which showed a positive treatment response, highlighting the complexities of diagnosing and treating SP in unusual locations.
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Background: Varicella is a very common childhood infectious disease. It is generally benign, but it can lead to fatal complications. Our study aimed to describe the clinical and therapeutic profile of varicella based on consultations in the pediatric emergency department, to determine the incidence of hospitalized varicella cases in the pediatric department for complementary management, and to specify the incidence of varicella complications in hospitalized patients.

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Henoch-Schönlein purpura (HSP) also known as rheumatoid purpura is the most common vasculitis in children. This condition affects small blood vessels, predominantly targeting the skin, digestive system, joints, and kidneys. Short-term prognosis mainly depends on abdominal complications, while long-term prognosis is mainly determined by the severity of kidney involvement, which occurs in about 35% of cases.

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Article Synopsis
  • Breast cancer is a significant global health issue, especially in Morocco, with this study focusing on awareness and self-examination practices among female university students.
  • A survey of 437 students revealed high awareness (95.3%) of breast cancer but only moderate knowledge (48.25%) and practical skills for self-examination (28.0%).
  • There is a pressing need for targeted educational programs to improve knowledge about breast cancer risk factors and promote early detection practices among young women.
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Cancer of the scrotum is a rare tumor. It is often not diagnosed early, and its treatment poses difficulties for practicing oncologists. We report the case of a patient treated for locally advanced squamous cell carcinoma (SCC) of the scrotum, with a review of the literature.

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Griscelli syndrome (GS) type II is a rare hereditary disorder characterized by partial albinism, immunodeficiency, and the subsequent development of hemophagocytic syndrome (HPS). Herein, we present a case involving a four-month-old infant admitted to our facility due to a prolonged fever complicated by HPS. The diagnosis of GS type 2 was established based on a constellation of clinical and laboratory findings: consanguinity, familial history of early infectious fatalities, ocular-cutaneous hypopigmentation, characteristic silvery hair sheen, onset of HPS, and notably, the pathognomonic appearance upon microscopic examination of a hair sample.

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Primary central nervous system (CNS) lymphoma is a rare and aggressive form of extranodal non-Hodgkin's lymphoma, limited to the brain, eyes, spinal cord, or leptomeninges without systemic involvement. This group of malignant tumors is characterized by a particular diagnostic, therapeutic, and evolutionary profile compared to other types of non-Hodgkin's lymphomas. We report a case of a young patient treated in our university hospital center for primary cerebral lymphoma who benefited from primary chemotherapy and then consolidation radiotherapy with good disease control and good tolerance.

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Benign intracranial hypertension (BIH) in children is recognized as elevated intracranial pressure without hydrocephalus or intracranial mass. It manifests differently in adults, with no apparent predilection for sex or weight. Headache, papilledema, and possibly sixth nerve palsy with visual field defects are the typical symptoms of this syndrome.

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[Evaluation of training in transfusion safety offered to medical students in Morocco].

Pan Afr Med J

May 2024

Service d´Hématologie et Greffe de Moelle Osseuse, Centre Hospitalier Universitaire Mohammed VI, Faculté de Médecine et de Pharmacie, Université Cadi Ayyad, Marrakech, Maroc.

Introduction: students worldwide receive little training on blood transfusion therapies during their time at medical schools and hospitals, then reformulation of academic programs is mandatory. Indications for blood transfusions are more frequent than recommended, which helps to increase the risks associated with this procedure. To overcome this, structured objective training on nursing care and procedures was organised with the topic of transfusion safety.

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Adnexal carcinomas are rare cutaneous malignancies arising from the eccrine and apocrine sweat glands, follicles and sebaceous glands. They occur mainly in elderly people. We report the case of a patient treated for locally advanced apocrine adnexal carcinoma of the thigh, with a review of the literature.

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Cancer of the penis is a rare tumor that occurs in the elderly. Because of its rarity, it is often not diagnosed early, and its treatment poses difficulties for practicing oncologists. We report the case of an elderly patient treated for locally advanced squamous cell carcinoma (SCC) of the penis, with a review of the literature.

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Adenoid cystic carcinoma (ACC) of the vulva represents a highly uncommon type of female malignancy. Due to the absence of specific treatment guidelines, such cases are typically managed by the treatment protocols for vulvar cancer. Here, we report the case of a 52-year-old woman who presented with a painful right vulvar mass, leading to a diagnosis of ACC of the vulva after biopsy and immunohistochemical analysis.

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Perception and expectation of Moroccan pharmacy students regarding e-learning in the context of COVID-19 pandemic lockdown.

Ann Pharm Fr

June 2024

Équipe de formulation et de contrôle qualité des produits de santé, laboratoire de pharmaceutique, faculté de médecine et de pharmacie, université Mohammed V de Rabat, Rabat, Morocco; Centre hospitalier universitaire Ibn Sina, Rabat, Morocco.

Purpose: Online learning, or e-learning, has grown exponentially in recent years, not least because the COVID-19 pandemic has forced many educational establishments to adopt distance learning modalities. In the field of pharmacy, where the acquisition of theoretical and practical knowledge is essential, the adoption of e-learning has attracted particular interest. The aim of this study is to analyze the feedback received by pharmacy students from different faculties in the country following the introduction of new learning methods during the Covid pandemic.

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Cystic echinococcosis (CE), stemming from the larval stage of the cestode , stands as a widespread parasitic zoonosis primarily afflicting the liver and lungs. However, instances in the inguinal region are exceptionally infrequent. We present a distinctive case involving a 49-year-old female with a progressively enlarging inguinal mass over a five-year period, characterized by the absence of hepatic or pulmonary involvement.

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Williams-Beuren syndrome is a rare genetic disease (1/20 000) characterized by a microdeletion at 7q11.23 encompassing about 28 genes, including the elastin gene, ELN. It is a sporadic disease in the majority of cases.

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Natural disasters cause immense damage and disruption to the environment, human lives, and property, posing a threat to safety and well-being. These disasters annually affect individuals and communities, severely impacting mental health. Research indicates a significant link between catastrophic events and an increased risk of mental disorders, including anxiety, depression, substance use, and post-traumatic stress disorder (PTSD).

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Background: The potential reappearance and/or expansion of vector-borne diseases is one of the terrifying issues awaiting humanity in the context of climate change. The presence of competent Anopheles vectors, as well as suitable environmental circumstances, may result in the re-emergence of autochthonous Malaria, after years of absence. In Morocco, international travel and migration movements from Malaria-endemic areas have recently increased the number of imported cases, raising awareness of Malaria's possible reintroduction.

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Endometriosis is a frequent gynecological pathology. Digestive localization complicated by acute intestinal obstruction is exceptionally rare. We herein report a case involving a 48-year-old woman who had a long-term history of endometriosis symptoms.

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[Bilateral sub-acute upper limb ischemia revealing Horton's disease, a rare presentation : A case report and literature review].

Ann Cardiol Angeiol (Paris)

February 2024

Département de Chirurgie Vasculaire, Université Mohammed Premier, Centre Hospitalier Universitaire Mohammed VI, Oujda, Maroc. Electronic address:

Study's Goal: Our goal is to enrich the medical literature by sharing our experience in managing a case of sub-acute upper limb ischemia that revealed Horton's disease. This is particularly relevant given the current lack of well-established guidelines.

Introduction: Acute upper limb ischemia is rarely seen in Horton's disease.

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[HER2 epidermal growth factor receptor, tests used to look for its amplification in breast cancer: Principles and limitations].

Bull Cancer

December 2023

Laboratoire d'anatomie et cytologie pathologique, centre hospitalier universitaire Mohammed VI Tanger-Tétouan-Al Hoceima (TTA), 90000 Tangier, Maroc; Université Abdelmalek-Essaadi, faculté de médecine et de pharmacie de Tangier, Tangier, Maroc.

HER2-positive breast cancer accounts for 20 % of all invasive breast cancers. It is associated with increased recurrence, a higher risk of brain metastases and a shorter overall survival than luminal A and B cancers. The presence of ERBB2 gene amplification is predictive of a good response to anti-HER2 therapies.

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