271 results match your criteria: "Centre for Spinal Studies and Surgery[Affiliation]"
Eur Spine J
January 2023
Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UH, UK.
Background: Despite the heterogeneity of chronic lower back pain aetiologies, cluneal nerve entrapment remains underdiagnosed and poorly understood with few studies discussing the efficacy of its surgical release.
Objective: The current study opts to conduct a systematic review reporting on the efficacy of cluneal nerve surgical decompression in patients with an established diagnosis who fail conservative treatment. We aimed to systematically evaluate the literature regarding the clinical outcomes, recurrence of symptoms and revision rates of surgical intervention.
JBJS Case Connect
April 2022
The Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, United Kingdom.
Case: "Baastrup's disease" is a relatively common anatomical condition, controversially recognized as a possible cause of back pain but frequently missed by clinicians of different specialties. We present a rare case of Baastrup's disease causing compression to the cauda equina nerves due to the formation of a large pseudotumoral epidural mass. The patient underwent a successful surgical decompression with remarkable improvement in her neurological presentation.
View Article and Find Full Text PDFBMJ Open
June 2022
Health Care of the Older People, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Introduction: Vertebral fragility fractures (VFFs) are the most common type of osteoporotic fracture found in older people, resulting in increasing morbidity and excess mortality. These fractures can cause significant pain, requiring admission to hospital. Vertebroplasty (VP) is effective in reducing pain and allowing early mobilisation in hospitalised patients.
View Article and Find Full Text PDFOsteoporos Int
August 2022
Depart HCOP, Nottingham University Hospitals NHS Trust, Nottingham, UK.
BMJ Open
May 2022
Department of Healthcare for Older People, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Objective: To determine the feasibility of designing and conducting a definitive trial to evaluate the effectiveness of sacral fracture fixation compared with non-surgical management among older people admitted with a lateral compression pelvic fragility fracture (PFF).
Design: Single-site, parallel, two-arm randomised controlled feasibility trial.
Setting: A UK tertiary centre hospital.
Rev Esp Cir Ortop Traumatol
March 2022
Orthopaedic and Traumatology Department, Institute of Orthopedics "Carlos E. Ottolenghi," Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. Electronic address:
Introduction And Objectives: Spinal metastases (SM) account for 5-30% of patients with cancer, causing pain, deformity and/or neurological deficit. Postoperative complications are a concerning subject and wound-related complications (WRC) may delay adjuvant treatment. The objective of this study was to analyze the incidence of WRC in patients with SM that underwent surgical treatment as well as possible risk factors related to the occurrence of complications.
View Article and Find Full Text PDFBMC Musculoskelet Disord
November 2021
Clinic of Orthopaedic Surgery, Ruhr University Bochum, Bad Oeynhausen, Germany.
Background: High primary stability is the key prerequisite for safe osseointegration of cementless intervertebral disc prostheses. The aim of our study was to determine the primary stability of intervertebral disc prostheses with two different anchoring concepts - keel and spike anchoring.
Methods: Ten ActivL intervertebral disc prostheses (5 x keel anchoring, 5 x spike anchoring) implanted in human cadaver lumbar spine specimens were tested in a spine movement simulator.
Spine Deform
March 2022
Instituto de Ortopedia y Traumatología "Carlos E. Ottolenghi", Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Purpose: The management of scoliosis and kyphoscoliosis in patients with Type 1 Neurofibromatosis (NF-1) among spinal surgeons is still challenging due to the severity of the deformity especially in dystrophic deformity types. This rapid and progressive condition is likely to be associated with dislocated rib heads into the spinal canal, hence representing a real dilemma on the decision making between its resection versus not resection during the corrective surgery, especially in patients with normal neurological status. The objective of this publication is to discuss the management options in this patient population through a literature review.
View Article and Find Full Text PDFJ Clin Med
August 2021
Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.
Objectives: To assess the reporting of study design and characteristics in multi-level degenerative cervical myelopathy (DCM) treated by posterior surgical approaches, and perform a comparison of clinical and radiographic outcomes between different approaches.
Methods: A literature search was performed in Embase and MEDLINE between 1995-2019 using a sensitive search string combination. Studies were selected by predefined selection criteria: Full text articles in English, with >10 patients (prospective) or >50 patients (retrospective), reporting outcomes of multi-level DCM treated by posterior surgical approach.
Geriatr Orthop Surg Rehabil
July 2021
The Centre for Spinal Studies and Surgery, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Background: Pubic rami fragility fractures are common in older people and result in significant morbidity and increased mortality. Co-existing fractures of the sacrum are common, but routinely missed. The aim of the study was to explore the perceptions in the assessment and treatment of pubic rami and sacral fragility fractures amongst healthcare professionals.
View Article and Find Full Text PDFInjury
October 2021
Faculty of Medicine, University of Malaya, Malaysia; Department for Healthcare of Older People, Nottingham University Hospital NHS Trust, United Kingdom; The Centre for Spinal Studies and Surgery, Nottingham University Hospitals NHS Trust, UK; National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre (BRC), United Kingdom.
Introduction: Patients that require hospital admission for vertebral fragility fractures were older, multimorbid, frail, have cognitive impairment and were in severe pain. This study aimed to describe the hospital treatment received in one UK university hospital with the purpose of proposing what hospital services should look like.
Method: This was an observational study of adults aged 50 years and over admitted to hospital over 12 months with an acute vertebral fragility fracture.
BMJ Case Rep
March 2021
The Centre for Spinal Studies and Surgery, Queen's Medical Centre Nottingham, University Hospital NHS Trust, Nottingham, UK.
is part of the commensal flora of the oral cavity, frequently associated with periodontal infections. We describe the case of a 49-year-old woman, on immunsuppressive therapy for multiple sclerosis, who presented with a 3-month history of debilitating back pain. She had a recent episode of periodontitis, and was under regular dental review.
View Article and Find Full Text PDFSpine Deform
July 2021
Centre for Spinal Studies and Surgery, D Floor, West Block, Queens Medical Centre, Derby Road, Nottingham, NG7 2UH, UK.
Study Design: A systematic review reporting on the efficacy of an ERAS protocol in patients undergoing spinal fusion for AIS.
Objective: To systematically evaluate the relevant literature pertaining to the efficacy of ERAS protocols with respect to the length of stay, complication, and readmission rates in patients undergoing posterior spinal corrective surgery for AIS. ERAS is a multidisciplinary approach aimed at improving outcomes of surgery by a specific evidence-based protocol.
JBJS Case Connect
October 2020
The Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals, Nottingham, United Kingdom.
Case: A 33-year-old woman underwent C5-6 anterior cervical discectomy and fusion for progressive cervical myelopathy using an intergrated cage screw construct. Five weeks postoperatively, she presented with neck pain, worsening gait, and weakness after a slight jerk, with imaging showing peri-implant transverse fracture in the C6 vertebral body across the site of Caspar distractor pins and tips of the integrated cage screws. She was treated conservatively with hard collar with close observation, and at 6 months, she was asymptomatic with complete fracture union on imaging.
View Article and Find Full Text PDFOsteoporos Int
April 2021
The Centre for Spinal Studies and Surgery, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Osteoporos Int
February 2021
Department for Healthcare of Older People, Queens Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, UK.
Spine (Phila Pa 1976)
April 2021
Department of Neurosurgery and Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA.
Study Design: International, multicenter, prospective, longitudinal observational cohort.
Objective: To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery.
Summary Of Background Data: Adult spinal deformity surgery is associated with high morbidity, including risk of new postoperative motor deficit.
Spine (Phila Pa 1976)
May 2021
Spine Unit, Neurosurgery Department, Hospital Español de Mendoza, Mendoza, Argentina.
Study Design: Case-report and literature review.
Objective: To depict main features of a potentially deleterious postoperative spinal fixation complication.
Summary Of Background Data: Tisular deposit of metal particles from prosthetic systems-metallosis-is an uncommon complication of spinal fixation surgery.
Eur Spine J
October 2021
Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Objective: The goal of this study was to review the incidence of complications and unplanned re-operations after surgery for metastatic spinal tumors.
Background: The spinal column is the most common osseous site for metastatic spread. The goals of the treatment of spinal metastases are largely palliative.
Bone Joint J
November 2020
The Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospital NHS Trust, Nottingham, UK.
Aims: To report the mid-term results of a modified self-growing rod (SGR) technique for the treatment of idiopathic and neuromuscular early-onset scoliosis (EOS).
Methods: We carried out a retrospective analysis of 16 consecutive patients with EOS treated with an SGR construct at a single hospital between September 2008 and December 2014. General demographics and deformity variables (i.
Asian Spine J
October 2020
The Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
As a respiratory pathogen, the novel coronavirus is commonly associated with aerosol-generating procedures. However, it is currently unclear whether spinal surgical procedures pose an additional risk of viral transmission to the surgical team. We reviewed the available evidence to ascertain the presence of coronavirus disease 2019 (COVID-19) blood viremia and the virus' blood transmissibility, as well as evidence of blood-aerosol generation and operating room contamination from spinal surgical procedures.
View Article and Find Full Text PDFEur Spine J
December 2020
Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Introduction: Surgical approaches to pathologies of the L5 vertebra constitute a significant challenge. Our aim was to review the efficacy and safety of the surgical approaches to L5 corpectomy and reconstruction across the range of presenting pathology.
Materials And Methods: This systematic review was conducted according to PRISMA guidelines, and databases were searched from 1970 to January 2020.
World Neurosurg
August 2020
Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Division of Neurosurgery, Krembil Neuroscience Centre, University Health Network, Toronto, Ontario, Canada. Electronic address:
Surgery should be considered for patients with metastatic epidural spinal cord compression (MESCC) with a life expectancy of ≥3 months. Given the heterogeneity of the clinical presentation and outcomes, clinical prognostic models (CPMs) can assist in tailoring a personalized medicine approach to optimize surgical decision-making. We aimed to develop and internally validate the first CPM of health-related quality of life (HRQoL) and a novel CPM to predict the survival of patients with MESCC treated surgically.
View Article and Find Full Text PDFEur Spine J
December 2020
Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, NG7 2UH, UK.
Study Design: A systematic review and meta-analysis.
Objective: The purpose of this study was to evaluate the clinical outcome and safety of sacroplasty for patients with secondary metastatic lesions to the sacrum.
Methods: Several databases, including the Cochrane library, PubMed and EMBASE, were systematically searched to identify potentially eligible articles in English language.
Asian Spine J
April 2021
The Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospitals, Nottingham, UK.
Study Design: Prospective study.
Purpose: Yellow flags are psychosocial associated with a greater likelihood of progression to persistent pain and disability. These are referred to as obstacles to recovery.