293 results match your criteria: "Centre for Nanobiotechnology[Affiliation]"

Investigating the potential use of an oleaginous bacterium, Rhodococcus opacus PD630, for nano-TiO remediation.

Environ Sci Pollut Res Int

August 2020

Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences building, Indian Institute of Technology Madras, Chennai, 600036, India.

The occurrence of titanium dioxide nanoparticles (nTiO), in the effluents released from wastewater treatment plants, has raised concerns. The fate of nTiO and their potential impact on organisms from different ecosystems are widely investigated. For the first time, in this work, we report the responses of an oleaginous bacteria Rhodococcus opacus PD630, belonging to an ecologically important genus Rhodococcus to environmentally relevant concentrations of nTiO under dark and UV light conditions.

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In this paper, we report the use of bimetallic hollow nanostructures (BHNS), consisting of gold and silver metals, for colorimetric detection of mercury. The sodium dodecyl sulphate (SDS)-capped BHNS were prepared by galvanic etching of silver nanoparticles (AgNPs) using gold chloride resulting in a partially hollow AgNPs with the gold layer at its surface. These BHNS were interacted with an aqueous solution of mercury ions (Hg) in the concentration range of 10 pM-10 mM.

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The growing usage of nanoscale zerovalent iron particles (nZVI) in the remediation of soil, ground/surface water has elicited large-scale environmental release triggering human exposure. The size of nanomaterials is a key regulator of toxicity. However, the effect of a variable size of nZVI on genotoxicity is unexplored in human cells.

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Advances in oral cancer detection.

Adv Clin Chem

August 2019

Centre for Nanobiotechnology, Vellore Institute of Technology, Vellore, India. Electronic address:

High incidence of oral carcinoma and its late-stage presentation are the major global healthcare issues. The World Health Organization (WHO) has set early diagnosis and prevention of oral cancer as their primary objective. It is important to consider the time of oral screening, as it plays a pivotal role in understanding the disease prognosis.

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Recently, the concerns about micro- and nano-plastics (NPs) toxicity have been increasing constantly, however the investigations are quiet meager. The present study provides evidences on the toxicological prospectives of virgin-, coronated- and isolated-NPs on human blood cells and Allium cepa root tip, respectively. Several plasma proteins displayed strong affinity towards NPs and produced multi-layered corona of 13 nm to 600 nm size.

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Titanium dioxide nanoparticles (TiO NPs) find applications in our day-to-day life because of unique physicochemical properties. Their release into the aquatic environment poses a possible risk to the organisms. However, the continuing exposure of NPs might reduce their bioavailability to marine organisms owing to aggregation and sedimentation in the aqueous systems thus significantly reducing their toxic impact.

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The use of P25 TiO NPs in consumer products, their release, and environmental accumulation will have harmful effects on the coastal ecosystems. The sensitivity to TiO NPs may vary depending on the structural property and physiological mechanism of algal species. Therefore, the present study investigates the differences in sensitivity of two marine algae, Dunaliella salina and Chlorella sp.

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The rising threat of vector-borne diseases and environmental pollution has instigated the investigation of nanotechnology-based applications. The current study deals with a nanotechnological application involving the usage of nanometric pesticides such as permethrin nanoemulsion. The mean droplet diameter and zeta potential of the prepared permethrin nanoemulsion were found to be 12.

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Histamine is known to be a principal causative agent associated with marine food poisoning outbreaks worldwide, which is typically formed in the contaminated food by decarboxylation of histidine by bacterial histidine decarboxylase. Upon quantification of histamine in different food products, one can comment on the quality of the food and use it as an indicator of the good manufacturing practices and the state of preservation. The United States Food and Drug Administration (FDA) has established 50 ppm (50 mg/kg) of histamine as the chemical index for fish spoilage.

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In the current study, the effect of different types of titanium dioxide (TiO) nanoparticles (NPs) (rutile, anatase, and mixture) was analyzed on Ceriodaphnia dubia in the presence of algae under distinct irradiation conditions such as visible and UV-A. The toxicity experiments were performed in sterile freshwater to mimic the chemical composition of the freshwater system. In addition, the oxidative stress biomarkers such as MDA, catalase, and GSH were analyzed to elucidate the stress induced by the NPs on daphnids.

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The occurrence of various antibiotics in natural waters poses an emerging environmental concern. Tetracycline (TC) is a frequently used antibiotic in human therapy, veterinary industry, and agricultural sectors. In the current study, TC removal from aqueous solutions was studied using binary Nickel/nano zero valent iron particles (NiFe nano particles) and in-situ NiFe nanoparticles coated sand (IS-NiFe).

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Article Synopsis
  • * The study investigates how different types of functionalized microplastics affect the toxicity of TiO NPs on marine algae (Chlorella sp.), finding that TiO NPs are significantly toxic while microplastics have minimal toxicity at higher concentrations.
  • * Results indicate that certain microplastics, like plain and aminated polystyrene, enhance the toxicity of TiO NPs through oxidative stress, while carboxylated polystyrene microplastics may reduce toxicity due to aggregation in the marine environment. *
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Sea weeds are valuable natural assets in aquaculture due to the presence of various bioactive active metabolites in them. Successful fish production and maintenance of disease free culturing systems in aquaculture with environment friendly practices is often affected by various environmental factors. Disease causing pathogens is one of the major factors.

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The increasing load of nanoplastic pollution in the environment has become a major concern toward human and environmental safety. The current investigation mainly focused on assessing the toxic behavior of nanoplastics (polystyrene nano-spheres (PNS)) toward blood cells and marine crustacean. The study also investigated the temporal stability of PNS under different water matrices and its size-dependent sedimentation behavior in the sea water dispersion.

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Long-term application and extensive use of synthetic insecticides have resulted in accumulating their residues in food, milk, water, and soil and cause adverse health effects to human and ecosystems. Therefore, application of natural insecticides in agriculture and public health sectors has been increased as alternative to synthetic insecticides. The question here is, are all natural insecticides safe.

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Pseudomonas aeruginosa is a pathogenic biofilm forming bacteria which exist in wide range of environments such as water, soil and human body. In an earlier study, we used a system biology approach based analysis of biofilm forming genes of P. aeruginosa and their possible role in TiO nanoparticle binding.

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Ala-geninthiocin, a new broad spectrum thiopeptide antibiotic, produced by a marine Streptomyces sp. ICN19.

J Antibiot (Tokyo)

February 2019

International Centre for Nanobiotechnology (ICN), Centre for Marine Science and Technology (CMST), Manonmaniam Sundaranar University, Rajakkamangalam-629502, Kanyakumari District, Tamil Nadu, India.

Bioassay-guided screening of antibacterial compounds from the cultured marine Streptomyces sp. ICN19 provided Ala-geninthiocin (1), along with its known analogs geninthiocin (2) and Val-geninthiocin (3) and the indolocarbazole staurosporine (4). The structure of 1 was determined on the basis of 1D and 2D NMR spectra and ESI-HRMS.

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Nanopriming with zero valent iron (nZVI) enhances germination and growth in aromatic rice cultivar (Oryza sativa cv. Gobindabhog L.).

Plant Physiol Biochem

June 2018

Department of Botany, Centre of Advanced Studies, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700 019, India. Electronic address:

Engineered nanoparticles are utilized in agriculture for various purposes. They can be used as fertilizer, carrier for macro/micro nutrients or priming agents. Various nanoparticles are reported to have toxicity at very high doses, but at optimum concentration, they can be beneficial for plant growth and development.

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There has recently been an increase in the usage of TiO nanoparticles (NPs). P25 TiO NPs, a mixture of anatase and rutile phase in 3:1 ratio, are generally used for photocatalytic applications because both phases exhibit a synergistic effect on the photocatalytic activity of the TiO NPs. In the present study, increased toxicity of UVA-pre-irradiated P25 TiO NPs on freshwater algae Scenedesmus obliquus was assessed under visible light and dark exposure conditions at actual low concentrations (0.

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Article Synopsis
  • The study investigates the environmental impact of increasing use of ZnO particles, focusing on their transfer from algae (Scenedesmus obliquus) to daphnia (Ceriodaphnia dubia).
  • It finds that the toxicity and absorption of ZnO particles depend on their size and concentration, with smaller particles (50 nm) causing greater harm.
  • Daphnia that fed on ZnO-exposed algae showed significant decreases in survival (15-20%) and accumulated Zn, indicating potential biomagnification in the food chain.
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Owing to the increase in the usage of titanium dioxide nanoparticles (TiO NPs), their release into the aquatic environment is inevitable. In the aquatic ecosystem, TiO NPs can bio-magnify at various trophic levels in the food chain through dietary exposure. In the current study, the trophic transfer potential of two crystalline phases of TiO anatase and rutile nanoparticles (individual as well as a binary mixture) has been evaluated in the lake water matrix using algae-daphnia system.

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Bionanocomposites fabricated using metal nanoparticles serve a wide range of biomedical applications viz., site targeted drug delivery, imaging etc. Theranostics emerge as an important field of science, which focuses on the use of single entity for both disease diagnosis and treatment.

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A systems biology approach was used to study all the biofilm related genes of P. aeruginosa PAO1, and the interaction of titanium dioxide (TiO) anatase with biofilm related proteins. Among the 71 genes, the interactions of all the nodal pairs were extracted by STRING 10.

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Polysaccharide from red seaweed Gracilaria folifera has an interesting functional property of antioxidant activity and prebiotic effect. A feeding trial experiment was directed to examine the effect of probiotic bacteria Bacillus vireti 01 microencapsulated with G. folifera polysaccharide against freshwater prawn M.

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The increasing risk of vector-borne diseases and the environmental pollution in the day-to-day life due to the usage of the conventional pesticides makes the role of nanotechnology to come into the action. The current study deals with one of the applications of nanotechnology through the formulation of neem urea nanoemulsion (NUNE). NUNE was formulated using neem oil, Tween 20, and urea using the microfluidization method.

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