293 results match your criteria: "Centre for Nanobiotechnology[Affiliation]"

Globally, aquaculture has faced serious economic problems due to bacterial, viral, and various other infectious diseases of different origins. Even though such diseases are being detected and simultaneously treated with several therapeutic and prophylactic methods, the broad-spectrum activity of vaccines plays a vital role as a preventive measure in aquaculture. However, treatments like use of antibiotics and probiotics seem to be less effective when new mutant strains develop and disease causing pathogens become resistant to commonly used antibiotics.

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With the prodigious use of plastics in the industrial sector and daily life, plastic has become one of the fastest-growing sources of pollution in the aquatic environment. Therefore, ingestion of micro/nanoplastics (MP/NPs) by aquatic organisms is inevitable. But the knowledge on the definite effect, ontogenetic transfer, and translocation of NPs remains incipient.

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Myeloid cell leukemia-1 (MCL1), an anti-apoptotic BCL-2 family protein plays a major role in the control of apoptosis as the regulator of mitochondrial permeability which is deregulated in various solid and hematological malignancies. Interaction of the executioner proteins Bak/Bax with anti-apoptotic MCL1 and its cellular composition determines the apoptotic or survival pathway. Mutations act at various levels in the apoptotic process and can contribute to disease.

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Article Synopsis
  • Silicon dioxide nanoparticles (nSiO) are widely used and released into the environment, affecting their behavior and potential ecological impacts.
  • The study examines how factors like pH, ionic strength, and humic acid influence the stability and aggregation of nSiO in water.
  • Findings indicate that these parameters significantly affect nSiO sedimentation and transport, emphasizing the role of shear forces and various water systems on their distribution in the environment.
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The increased usage of titanium dioxide nanoparticles (nTiO) in consumer products has led to their prevalence in freshwater systems. Nanoplastics, a secondary pollutant, can significantly influence the toxic effects of nTiO in freshwater organisms. The present study investigates the role of fluorescent nanoplastics (FNPs) in modifying the harmful effects of P25 nTiO in freshwater algae Scenedesmus obliquus.

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Nanoparticles in Clinical Translation for Cancer Therapy.

Int J Mol Sci

February 2022

Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China.

The advent of cancer therapeutics brought a paradigm shift from conventional therapy to precision medicine. The new therapeutic modalities accomplished through the properties of nanomaterials have extended their scope in cancer therapy beyond conventional drug delivery. Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner.

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In the recent era, carbon dots (C-dots) have been extensively considered as a potential tool in drug delivery analysis. However, there have been fewer reports in the literature on their application in the sensing of amino acids. As part of our ongoing research on coconut-husk-derived C-dots, we synthesized C-dots under different temperature conditions and utilized them in the field of amino acid sensing and found them to be highly selective and sensitive towards tyrosine.

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Increasing usage of both nanomaterials and pharmaceuticals and their unabated release to the marine ecosystem pose a serious concern nowadays. The toxicity of the mixture of TiO NPs and tetracycline (TC) in the marine species are not very well covered in prior literature. The current study explores the joint toxic effects of TiO NPs and TC in a simulated marine food chain: Chlorella sp.

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Potential health risk caused by heavy metal associated with seafood consumption around coastal area.

Environ Pollut

February 2022

Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, TN, India. Electronic address:

The current study investigated seasonal fluctuations in diversity of fish and heavy metal concentrations in coastal areas, as well as the possible human health risks associated by the heavy metals (Mercury, Lead, Chromium, Cadmium, Copper and Zinc). From five different locations across the coastal area, 44 finfish species from 11 orders and 33 families were collected. Four finfish species such as Mugil cephalus, Lates calcarifer, Etroplus suratensis, and Chanos chanos were used to estimate and assess the heavy metal concentrations based on abundance and distribution across coastal area.

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In the present study, ZnO-FeO nanoparticles were synthesized using the leaves of Camellia sinensis and immobilized in crosslinked alginate-chitosan polymer beads and tested for their photocatalytic applications. The prepared nanocomposite was used for the simultaneous adsorption and photocatalytic degradation of acid violet 7 (AV7) dye. The optimization of reaction conditions ensured higher dye removal efficacy up to 94.

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Emerging trends in point-of-care sensors for illicit drugs analysis.

Talanta

February 2022

Ricovr Healthcare Inc, 252 Nassau St., Princeton, NJ, 08542, USA. Electronic address:

Consumption of illicit narcotic drugs and fatal or criminal activities under their influence has become an utmost concern worldwide. These drugs influence an individual's feelings, perceptions, and emotions by altering the state of consciousness and thus can result in serious safety breaches at critical workplaces. Point-of-care drug-testing devices have become the need-of-the-hour for many sections such as the law enforcement agencies, the workplaces, etc.

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Widespread usage of nano-TiO in various commercial products and their consequent release into the seawater pose a severe threat to marine biota. Nanoplastics, a secondary pollutant in the marine environment, could influence adverse effects of nano-TiO. The main goal of the present study was to investigate the influence of the differently functionalized polystyrene nanoplastics (COOH-PSNPs, NH2-PSNPs, and Plain-PSNPs) on the acute toxic effects of P25 nano-TiO in marine algae Chlorella sp.

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FeO-urea nanocomposites as a novel nitrogen fertilizer for improving nutrient utilization efficiency and reducing environmental pollution.

Environ Pollut

January 2022

Centre of Advanced Study, Department of Botany, Calcutta University, 35, Ballygange Circular Road, Kolkata-19, India. Electronic address:

Almost 81% of nitrogen fertilizers are applied in form of urea but most of it is lost due to volatilization and leaching leading to environmental pollution. In this regard, slow-release nano fertilizers can be an effective solution. Here, we have synthesized different FeO-urea nanocomposites with FeO NPs: urea ratio (1:1, 1:2, 1:3) ie.

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Background: Today, cosmetic products are very popular with both men and women to improve their appearance and increase their social acceptability.

Results: In this study, nano-sized (30-300 nm) plastic particles were isolated from the commercial face-scrubs and treated on the human keratinocytes. The observed adherence of polyethylene nano-plastics (PENPs), polystyrene NPs (PSNPs), and face-scrubs isolated nano-plastics (NPs) on the keratin layer reveals a significant attachment of NPs from the cosmetics that are applied on the skin for a short duration.

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Micro and nanoplastics are one of the major emerging environmental contaminants. Their impact on human health is less explored. There are several in vitro studies on their cellular uptake and accumulation, where micro and nanoplastics were mostly reported to be non-cytotoxic.

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The rising use of contaminants such as nanoparticles and microplastics has taken a heavy toll on the marine environment. However, their combined toxic effects on the species across various trophic levels remain quite unexplored. The aim of this study was to explore the effects of three surface-functionalized (carboxylated, plain, and aminated) polystyrene microplastics on nano-TiO toxicity across two trophic levels containing Chlorella sp.

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Nanozymes to fight the COVID-19 and future pandemics.

Environ Chem Lett

May 2021

Amity Centre for Nanobiotechnology and Nanomedicine (ACNN), Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, 303002 Rajasthan India.

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The objective of this study was to develop bimetallic core-shell Pd/Fe nanoparticles on the surface of aerobic microbial granules (Bio-Pd/Fe) and to evaluate their dye removal potential using a representative dye, methyl orange (MO). The aerobic microbial granules (1.5 ± 0.

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Elucidating ROS signaling networks and physiological changes involved in nanoscale zero valent iron primed rice seed germination sensu stricto.

Free Radic Biol Med

August 2021

Centre of Advanced Study, Department of Botany, Calcutta University, 35, Ballygange Circular Road, Kolkata-19, India. Electronic address:

Reactive oxygen species (ROS) play pivotal roles during seed dormancy and germination. Metabolically active cells of seeds generate ROS and successful germination is governed by internal ROS contents, maintained within an optimum "oxidative window" by several ROS scavengers. Although ROS was previously considered hazardous, optimum ROS generation in seeds can mediate early seed germination by acting as messengers for cell signaling involved in endosperm weakening, stored food mobilization, etc.

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Nanopriming is a combination of nanoparticle treatment and a seed dressing technique that can increase seed quality, seedling vigour, yield and also imparts tolerance against biotic and abiotic stress. Here, nano-scale zero-valent iron (G-nZVI) was synthesized using fruit peel waste of Punica granatum L and their formation was validated from XRD and optical spectroscopic techniques. Later, the seeds were primed with G-nZVI at six different concentrations (0, 10, 20, 40, 80, and 160 mg L ) to determine the dose which is optimum for increasing germination percentage and seedling vigour of rice (Oryza sativa L.

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Cadmium selenide (CdSe) quantum dots cause genotoxicity and oxidative stress in Allium cepa plants.

Mutat Res Genet Toxicol Environ Mutagen

May 2021

Cell Biology and Genetic Toxicology Laboratory, Center of Advance Study, Department of Botany, 35, Ballygunge Circular Road, Kolkata, 700 019, India. Electronic address:

Quantum Dots (QDs), are considered as promising tools for biomedical applications. They have potential applications in agricultural industries, novel pesticide formulations, use in bio-labels and devices to aid genetic manipulation and post-harvest management. Since interactions with higher plants are of important environmental and ecological concern we investigated the cytotoxicity and genotoxicity of CdSe QDs in a model plant (Allium cepa) and established relationships between QDs genotoxic activity and oxidative stress.

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Covid 19 caused by novel strain SARS- CoV-2 has become a pandemic due to its contagious nature of infection. It enters by binding with ACE2 receptor present on the outer surface of a cell by cleaving S1/S2 with proteolytic protein Furin. Further viral replication or transcription then takes place with the help of main protease 3CLpro and polymerase RdRp.

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Nanoemulsions (NEs) of essential oil (EO) have significant potential to target microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and vaccines. Narrowing of drug discovery pipeline and the emergence of new viral diseases, especially, coronavirus disease, have created a niche to use NEs for augmenting currently available therapeutic options.

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Nano-Scale Zero Valent Iron (nZVI) Priming Enhances Yield, Alters Mineral Distribution and Grain Nutrient Content of L. cv. Gobindobhog: A Field Study.

J Plant Growth Regul

February 2021

Centre of Advanced Study, Department of Botany, Calcutta University, 35, Ballygange Circular Road, Kolkata, 700019 India.

Unlabelled: In recent decades, nano-scale zero valent iron is reported to have plant growth enhancement capacity under laboratory conditions, but till date, there is no report to highlight its effect on the growth and yield of field-grown plants. In this study, we have evaluated the potential of nZVI priming on rice yield. A two-year field study has been conducted with different concentrations (10, 20, 40, and 80 mg l) of nZVI for seed priming.

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