1,045 results match your criteria: "Centre for Menstrual Cycle and Ovulation Research; University of British Columbia[Affiliation]"

Background: A normal luteal function is an essential factor for maintaining pregnancy; luteal phase deficiency decreases embryo implantation and pregnancy rate and increases the early miscarriage rate. In stimulated in vitro fertilization-embryo transfer (IVF-ET) patients, luteal phase support (LPS) is achieved by the exogenous supplementation with progesterone to increase endometrial receptivity and pregnancy. While several protocols exist, no commonly accepted protocol has been established for optimal luteal support after IVF-ET to date, the purpose of this study was to investigate the effect of two different luteal phase support protocols in patients undergoing assisted reproductive technologies.

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Menstrual Health Literacy, Equity and Research Priorities.

J Obstet Gynaecol Can

December 2024

Women's Health Research Institute, Vancouver, BC; Centre for Menstrual Cycle and Ovulation Research, University of British Columbia, Vancouver, BC; Division of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC; School of Population and Public Health, University of British Columbia, Vancouver, BC.

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Connaissances, équité et priorités de recherche en santé menstruelle.

J Obstet Gynaecol Can

December 2024

Women's Health Research Institute, Vancouver, BC; Centre for Menstrual Cycle and Ovulation Research, University of British Columbia, Vancouver, BC; Division of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC; School of Population and Public Health, University of British Columbia, Vancouver, BC.

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Test-retest reliability of strength, power, agility, and sprint performance in female team handball players.

J Sci Med Sport

November 2024

School of Sport Sciences, UiT The Arctic University of Norway, Norway; Department of Health Sciences, Swedish Winter Sports Research Centre, Mid Sweden University, Sweden.

Objectives: This study assessed the test-retest reliability of athletic performance tests in a cohort of trained Norwegian female handball players, as well as a sub-analysis of the test-retest reliability for naturally menstruating players.

Design: Eighteen handball players (naturally menstruating: n = 8) completed performance test batteries on three separate occasions.

Methods: The performance test battery included: a 1-repetition Smith machine back squat, maximal handgrip strength tests, counter-movement jumps, squat jumps, a modified agility T-test, and 15-m linear sprints.

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Retraction Note: A one-year observational cohort study of menstrual cramps and ovulation in healthy, normally ovulating women.

Sci Rep

November 2024

Endocrinology and Metabolism, Centre for Menstrual Cycle and Ovulation Research (CeMCOR), University of British Columbia, 2775 Laurel Street, 4th Floor, Vancouver, BC, V5Z 1M9, Canada.

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Unveiling the Neurotransmitter Symphony: Dynamic Shifts in Neurotransmitter Levels during Menstruation.

Reprod Sci

November 2024

Societe Francophone de Nutritherapie et de Nutrigenetique Appliquee, Villeurbanne, France.

The menstrual cycle is an intricate biological process governed by hormonal changes that affect different facets of a woman's reproductive system. This review provides an overview of neurotransmitter alterations during different menstrual cycle phases and their effects on physiology and psychology. During the follicular phase, rising estrogen levels increase serotonin synthesis, enhancing mood, cognition, and pain tolerance.

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Article Synopsis
  • Alpacas exhibit unique reproductive traits, including induced ovulation and differences in uterine horn gestation rates, but challenges like low fertility and high embryonic mortality persist, prompting further study of the uterine wall changes during the luteal phase.
  • The research aimed to investigate histological changes in the uterine wall of alpacas, analyzing samples from both left and right uterine horns after inducing ovulation via GnRH or natural mating.
  • Results indicated that copulation (G2) led to thicker uterine layers and larger gland areas in the left horn, suggesting better developmental conditions during the luteal phase, and highlighting new insights into alpaca reproductive physiology.
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Chronic inflammation is a key characteristic of polycystic ovary syndrome (PCOS) and is associated with follicular dysplasia in PCOS. PCOS patients treated with 1000 mg resveratrol (RES) daily for 3 months showed significant improvement in menstrual cycle regularity compared to the placebo group. This investigation explores potential impact of RES on a rat model of PCOS.

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Purpose: The purpose of this study was to describe the implementation of menstrual-cycle (MC) and hormonal-contraceptive (HC) tracking among Gaelic Football players, including the characterization of MC status and symptomatology, and to examine the effect of MC and oral-contraceptive-pill phases on daily wellness.

Methods: Fourteen highly trained players (age 24.2 [3.

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Background: Anti-Müllerian hormone (AMH) is a widely used marker for estimating ovarian reserve, and it may predict response to ovarian stimulation. While AMH is considered a stable, cycle-independent marker, studies have shown it can exhibit significant fluctuations based on factors like age, reproductive stage, and menstrual cycle phase. The fluctuations in AMH levels can make it challenging to predict individual responses accurately, particularly when the AMH is not measured in the COS cycle.

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Purpose: This study aimed to evaluate the comparative reproductive outcomes of ovarian stimulation combined with intrauterine insemination using partner's sperm (OS-IUI) in eumenorrheic and normogonadotropic oligomenorrheic women.

Method: A retrospective cohort study was conducted, including 3833 couples who underwent 5920 cycles of OS-IUI between June 2013 and March 2019. Participants were stratified into two cohorts based on menstrual regularity: eumenorrheic and normogonadotropic oligomenorrheic.

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Article Synopsis
  • The study investigates the length variance of the luteal phase compared to the follicular phase in healthy, premenopausal women with normal menstrual cycles.
  • Results showed that while there were some ovulatory disturbances, the variability in follicular phase lengths was significantly greater than in luteal phase lengths.
  • The research involved 53 women over a year, tracking their menstrual cycles and related data to analyze the differences in phase lengths within the participants' cycles.
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Article Synopsis
  • * Factors such as older age, White ethnicity, substance use history, and food insecurity were found to be independently associated with amenorrhea among women with HIV.
  • * The study highlights the importance of addressing modifiable risk factors and encourages healthcare providers to regularly assess menstrual health and support socio-structural changes to improve outcomes for women with HIV.
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Article Synopsis
  • The study evaluated the effect of adding 4 mg estradiol valerate to progesterone for luteal support in IVF cycles where patients had low estrogen levels after hormone trigger.
  • Conducted at a reproductive center with 241 participants, the trial showed no significant difference in ongoing pregnancy rates between the estradiol group and the control group.
  • However, the estradiol group had no biochemical miscarriages and a higher clinical pregnancy rate in blastocyst transfers, suggesting potential benefits in these specific cases.
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Introduction: In the realm of natural frozen-thawed embryo transfer (FET) cycles, the application of luteal phase support (LPS) is a prevalent practice, primarily due to its beneficial impact on reproductive outcomes. Among the various LPS medications, human chorionic gonadotropin (hCG) is one that exerts its function on both the corpus luteum and the endometrium.

Objective: To evaluate the effect of hCG administration as LPS on reproductive outcomes in natural FET cycles.

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Mature oocyte found during ovarian tissue cryopreservation in an early adolescent female.

Zhejiang Da Xue Xue Bao Yi Xue Ban

August 2024

Reproductive Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.

A 15-year-old female with Hodgkin's lymphoma underwent ovarian tissue cryopreservation for preserving fertility in Reproductive Department of Sir Run Run Shaw Hospital, Zhejiang University School of Medical after receiving one course of chemotherapy. During the ovarian tissue cryopreservation, one MⅡmature oocyte and three germinal vesicle oocytes were found. The three immature oocytes underwent maturation but failed.

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Associations of luteal phase changes in vagally mediated heart rate variability with premenstrual emotional changes.

BMC Womens Health

August 2024

Institute of Medical Psychology, Center for Psychosocial Medicine (ZPM), Heidelberg University Hospital, Ruprecht Karl University of Heidelberg, Bergheimer Str. 20, Heidelberg, 69115, Germany.

Article Synopsis
  • * It involved 31 participants who reported daily negative emotions and attended lab visits during different menstrual phases to assess vmHRV and hormone levels.
  • * Findings indicate that most women experienced typical vmHRV decreases during the luteal phase, but only those with unusual increases in vmHRV experienced significant worsening of negative emotions before their period.
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Article Synopsis
  • Most menstrual cycle studies have focused on small, lab-based samples of young women, limiting understanding of broader impacts across different ages and real-life conditions.
  • This study involved 116 healthy females, comprising young and midlife groups, using wearable tech to monitor finger temperature, heart rate, physical activity, and self-reported symptoms throughout the menstrual cycle.
  • Findings revealed that temperature fluctuated with the menstrual cycle phases, HR was lowest during menses for both groups, but sleep metrics remained stable regardless of cycle changes.
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Objective: Less than half of servicewomen report loss of menses during initial military training. However, self-reported menstrual status may not accurately reflect hypothalamic-pituitary-ovarian (HPO) axis suppression and may underestimate reproductive health consequences of military training. Our aim was to characterise HPO axis function during US Army Basic Combat Training (BCT) in non-hormonal contraceptive-using women and explore potential contributors to HPO axis suppression.

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Unlabelled: Recent methodological recommendations suggest the use of the "3-step method," consisting of calendar-based counting, urinary ovulation testing, and serum blood sampling, for the identification of subtle menstrual disturbances (SMDs). However, the use of the 3-step method is not always feasible, so a less demanding combination of calendar-based counting and urinary ovulation testing, that is, the 2-step method, may be a viable alternative.

Purpose: To investigate the agreement between the 2- and 3-step methods for the detection of SMDs.

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Common marmosets are small New World monkeys. Since many of their biological mechanisms are similar to those of humans, marmosets are potentially useful for medical and human biology research across a range of fields, such as neuroscience, regenerative medicine, and development. However, there is a lack of literature describing methods for many basic experiments and procedures.

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Study Question: Does luteal estradiol (E2) pretreatment give a similar number of retrieved oocytes compared to no-pretreatment in advanced-aged women stimulated with corifollitropin alfa in an antagonist protocol?

Summary Answer: Programming antagonist cycles with luteal E2 gave similar number of retrieved oocytes compared to no-pretreatment in women aged 38-42 years.

What Is Known Already: Programming antagonist cycles with luteal E2 pretreatment is a valuable tool to organize the IVF procedure better and is safe without any known impact on cycle outcome. However, variable effects were observed on the number of retrieved oocytes depending on the treated population.

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Purpose: It is asserted that primary dysmenorrhea/menstrual cramps only occur in ovulatory menstrual cycles. Our first objective was to present detailed menstrual cramps information in normally ovulatory versus anovulatory cycles from a single-cycle cohort study during the SARS-CoV-2 Pandemic. Secondly, we reviewed the literature for cohort studies documenting both menstrual cramps and ovulation.

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[Comparative Study of the Embryo Development and Clinical Outcomes of 3 Ovarian Stimulation Protocols in Different Age Groups].

Sichuan Da Xue Xue Bao Yi Xue Ban

May 2024

( 230032) Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China.

Objective: The main purpose of this study is to compare the embryo development and clinical outcomes of women in different age groups undergoing fertilization (IVF) processes using gonadotrophin-releasing hormone (GnRH) antagonist protocol, GnRH agonist long protocol, and early follicular phase protocol. We aim to provide reliable reference for future clinical treatments.

Methods: We conducted a detailed analysis of patients who underwent treatment between January 2021 and February 2023.

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