Photoactive Herbal Compounds: A Green Approach to Photodynamic Therapy.

Photodynamic therapy (PDT) is a minimally invasive, alternative, and promising treatment for various diseases, including cancer, actinic keratosis, Bowen's disease, macular degeneration, and atherosclerotic plaques. PDT involves three different components, photosensitizers (PS), molecular oxygen, and light. The photoactivation of administered PSs using a specific wavelength of light in the presence of molecular oxygen leads to the generation of reactive oxygen species that leads to tumour cell death.

Purification of Bhallathaka (Semecarpus anacardium L.f.) enhanced anti-cancer activity.

Semecarpus anacardium L. F. commonly known as Bhallathaka, is an important Ayurvedic medicinal plant of the family Anacardiaceae.

Chemical profiling of selected Ayurveda formulations recommended for COVID-19.

Background: The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the global health concern since December 2019. It has become a big challenge for the researchers to find a solution for this newly evolved pandemic. In Ayurveda point of view, COVID-19 is a (epidemic disease), a situation where the environment-air, water, land, and seasons-is vitiated, causing a simultaneous manifestation of a disease among large populations.

Metabolite profiling of (L.) H. Rob. and its herbal formulation by tandem mass spectroscopic analysis.

is a medicinal plant commonly known as little ironweed is used in various traditional systems of medicines. In , it is known as and is used as remedy for many ailments. It has been reported to possess numerous biological properties including diaphoretic, anthelmintic, diuretic, lithontriptic, anti-inflammatory and anticancer activities.

LC/MS characterization of phenolic antioxidants of Brindle berry (Garcinia gummi-gutta (L.) Robson).

Characterisation of antioxidant fraction of the fruit of Garcinia gummi-gutta was done using liquid chromatography mass spectroscopic (LC/MS) analyses. Total poly phenolics and radical scavenging activity of various extracts such as acetone, methanol and hydroalcohol were estimated spectrophotometrically. The active extract was analysed by LC/MS in order to identify the molecular mass and tentative structures of major compounds.

Protocols for In Vitro Propagation, Conservation, Synthetic Seed Production, Embryo Rescue, Microrhizome Production, Molecular Profiling, and Genetic Transformation in Ginger (Zingiber officinale Roscoe.).

Ginger is a rhizomatous plant that belongs to the family Zingiberaceae. It is a herbaceous perennial but cultivated as annual, with crop duration of 7-10 months. Ginger is native to India and Tropical South Asia.

Protocols for In Vitro Propagation, Conservation, Synthetic Seed Production, Microrhizome Production, and Molecular Profiling in Turmeric (Curcuma longa L.).

Turmeric is a rhizomatous herbaceous perennial but cultivated as annual, belonging to the family Zingiberaceae. It is a native of India and South East Asia. The tuberous rhizomes or underground stems of turmeric are used from antiquity as condiments, a dye and as an aromatic stimulant in several medicines.

Gamma amino butyric acid accumulation in medicinal plants without stress.

Introduction: Gamma amino butyric acid (GABA) is an important ubiquitous four carbon nonprotein amino acid with an amino group attached to gamma carbon instead of beta carbon. It exists in different organisms including bacteria, plants, and animals and plays a crucial role in humans by regulating neuronal excitability throughout the nervous system. It is directly responsible for the regulation of muscle tone and also effective in lowering stress, blood pressure, and hypertension.

Bioassay directed isolation and biological evaluation of compounds isolated from Rubus fairholmianus Gard.

The in vitro and in silico analysis of Rubus fairholmianus acetone extract for antioxidant, antiproliferative, and anti-inflammatory activity led to the isolation of six compounds. Amongst all the six isolated compounds tested, 1-(2-hydroxyphenyl)-4-methylpentan-1-one (compound 1) and 2-[(3-methylbutoxy) carbonyl] benzoic acid (compound 2) were found to be more active in inhibiting BRCA and COX target proteins, which also showed the better results for DPPH and ABTS radical scavenging assays. The promising results of this investigation emphasize the importance of using R.

Quality parameters, fatty acid profiling and estimation of umbelliferone in grahaṇimihira tailam: An ayurvedic oil preparation.

Background: Grahaṇimihira tailam is an unexplored ayurvedic oil preparation which consists of 34 ingredients. The efficacy of this traditional ayurvedic medicine is undisputable. Proper clinical standardization of this formulation will go a long way in securing greater recognition for it.

Identification of phenolic antioxidants in Ipomoea mauritiana jacq. using spectrophotometric and mass spectroscopic studies.

Objective: Ipomoea mauritiana is used in both Ayurveda and folk medicine systems. The tuberous roots are known to be diuretic, depurative, carminative, and anthelmintic. The objective of the current study was to identify phenolic antioxidants from I .

Phenolic characterisation of selected Salacia species using LC-ESI-MS/MS analysis.

Phenolic characterisation was carried out on the leaf of three Salacia species such as Salacia chinensis, Salacia fruticosa and Salacia oblonga using liquid chromatography coupled with quadrupole time of flight mass spectrometry equipped with electrospray ionisation interface. The estimation of total phenolics was carried out spectrophotometrically using Folin-Ciocalteu method. HPLC diode-array detection has been used for the preliminary identification of phenolic compounds, and liquid chromatography and mass spectrometry analyses were employed for their characterisation.

Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug 'Patha', and its other source plants by ISSR markers.

Cissampelos pareira L. var. hirsuta (Buch.

Significance of gingers (Zingiberaceae) in Indian System of Medicine - Ayurveda: An overview.

Background: Family Zingiberaceae consists of the large number of medicinal plants and is well-known for its use in ethnomedicine and play a major role in Indian System of Medicine, Ayurveda.

Objective: The aim of this study is the documentation of Zingiberaceous plants used in Ayurveda, adding information to the systematics, vernacular names and chemistry with experimental data.

Materials And Methods: The live plants were collected from wild and successfully conserved at Herbal Garden of Arya Vaidya Sala, Kottakkal.

Total phenolics and total flavonoids in selected Indian medicinal plants.

Plant phenolics and flavonoids have a powerful biological activity, which outlines the necessity of their determination. The phenolics and flavonoids content of 20 medicinal plants were determined in the present investigation. The phenolic content was determined by using Folin-Ciocalteu assay.

In vitro propagation of two tuberous medicinal plants: Holostemma ada-kodien and Ipomoea mauritiana.

Medicinal plants are sources of important therapeutic aid for healing human diseases. The depletion of the wild resources has prompted conservation, propagation, and enhancement of resources for medicinal plants. Micropropagation offers an alternate method to propagate and improve medicinal plants through selection of high-yield lines and their efficient cloning.

A Reverse Phase HPLC-UV and HPTLC Methods for Determination of Plumbagin in Plumbago indica and Plumbago zeylanica.

A reverse phase HPLC method with UV detection has been developed and validated in order to quantify plumbagin, the bioactive marker of the roots of P. indica and P. zeylanica.

HPLC Estimation of berberine in Tinospora cordifolia and Tinospora sinensis.

A high-performance liquid chromatographic method for the estimation of berberine in the stem of Tinospora cordifolia (Willd.) Miers. ex Hook.