534 results match your criteria: "Centre for Healthcare Transformation[Affiliation]"

Background: International travel can increase the risk of exposure to infectious diseases including sexually transmissible infections (STI). Pre-travel medical consultation provides an opportunity for travel-related health risk assessments and advice. This study explored how travel medicine clinicians integrate sexual and reproductive health (SRH) services into clinical practice.

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Redefining hypnosis: A narrative review of theories to move towards an integrative model.

Complement Ther Clin Pract

February 2024

Child Health Research Centre, Centre for Children's Burns and Trauma Research, The University of Queensland, Brisbane, Australia; Australian Centre for Health Service Innovation and Centre for Healthcare Transformation, School of Public Health and Social Work, Queensland University of Technology, Brisbane, Australia.

Hypnosis is an ancient mind-body intervention that has regained interest with the surge of research in the last decade documenting its clinical validity. Yet, theoretical controversies and misconceptions prevail among theorists, clinicians, and the general public, impeding the understanding, acceptance, replication, and use of hypnosis. Providing adequate information, which dispels misconceptions and promotes more balanced views, is warranted to facilitate the implementation and adoption of hypnosis in clinical and research settings.

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Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice.

Sci Rep

January 2024

Center of Brain Behavior and Metabolism, Institute of Neurobiology, University of Lübeck, Marie Curie Street, 23562, Lübeck, Germany.

Article Synopsis
  • Thyroid hormones (THs) play a crucial role in regulating energy metabolism, particularly in the liver, where they influence lipid and cholesterol levels as well as overall energy availability.
  • A study using a mouse model of hypothyroidism found that low TH levels reduced activity, food intake, and body temperature primarily during the active phase, with minimal effects on liver gene expression compared to high TH levels.
  • Circadian analysis revealed changes in gene expression patterns related to cholesterol metabolism in low-TH mice, identifying 516 genes as potential markers for assessing liver TH state throughout the day.
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Aims: The aim of this study was to perform the first population-based description of the epidemiological and health economic burden of fracture-related infection (FRI).

Methods: This is a retrospective cohort study of operatively managed orthopaedic trauma patients from 1 January 2007 to 31 December 2016, performed in Queensland, Australia. Record linkage was used to develop a person-centric, population-based dataset incorporating routinely collected administrative, clinical, and health economic information.

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Implementing paediatric appropriate use criteria for endotracheal suction to reduce complications in mechanically ventilated children with respiratory infections.

Aust Crit Care

January 2024

Metro North Health, Herston Infectious Disease Institute, Queensland, Australia; School of Public Health, Faculty of Medicine, University of Queensland, St Lucia, Queensland, Australia.

Background: Endotracheal suction is used to maintain endotracheal tube patency. There is limited guidance to inform clinical practice for children with respiratory infections.

Objective: The objective of this study was to determine whether implementation of a paediatric endotracheal suction appropriate use guideline Paediatric AirWay Suction (PAWS) is associated with an increased use of appropriate and decreased use of inappropriate suction interventions.

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Associations of exposure to ambient fine particulate matter constituents from different pollution sources with semen quality: Evidence from a prospective cohort.

Environ Pollut

February 2024

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, China; The Key Laboratory of Major Autoimmune Diseases, 81 Meishan Road, Anhui Medical University, Hefei, Anhui, China. Electronic address:

The association between ambient fine particulate matter (PM) exposure and semen quality remains inconclusive, possibly due to variations in pollution sources and PM compositions. Studies investigating the constituents of PM have been hindered by small sample sizes, and research exploring the relationships between PM pollution sources and semen quality is lacking. To address this gap, we conducted a comprehensive study based on the Anhui prospective assisted reproduction cohort to evaluate the associations between semen quality and the constituents and pollution sources of PM.

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Exploring the Association between Hemochromatosis and Lower-Limb Venous Disease.

Adv Skin Wound Care

January 2024

In the School of Nursing, Queensland University of Technology, Queensland, Australia, Christina N. Parker, PhD, is Associate Professor; and Kathleen J. Finlayson, PhD, is Lecturer, Centre for Healthcare Transformation. Emma J. Hall, RN, is Clinical Nurse-Research Coordinator, Gold Coast Hospital and Health Service, Queensland, and Research Project Officer, Queensland University of Technology. Natasha Pitman, RN, is Registered Nurse, Infectious Diseases Unit, Princess Alexandra Hospital, Woolloongabba, Queensland. Wing Kei Chu, BMedLabSc, is Hematology and Blood Bank Scientist, QML Pathology, Murarrie, Queensland. Daniel F. Wallace, PhD, is Associate Professor, Queensland University of Technology. Acknowledgments: The authors acknowledge the valuable contribution of Tony Moorhead and Dianne Prince from Haemochromatosis Australia. The authors have disclosed no financial relationships related to this article. Submitted December 2, 2022; accepted in revised form February 3, 2023.

Objective: Chronic venous disease is a circulatory system dysfunction that has the potential to lead to venous leg ulceration. Although research on the influence of specific gene variants on chronic venous disease has been limited, a few studies have reported an association between hemochromatosis and chronic venous disease. However, no studies have looked at the prevalence of lower-limb venous disease and leg ulcers in people with hemochromatosis.

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Non-pharmacological interventions for chemotherapy-induced diarrhoea and constipation management: A scoping review.

Eur J Oncol Nurs

February 2024

School of Nursing, Faculty of Health, N block, Queensland University of Technology, Kelvin Grove, 4059, Australia; Cancer and Palliative Care Outcomes Centre, Centre for Healthcare Transformation, Queensland University of Technology, X block, 66 Musk Avenue, Kelvin Grove, 4059, Australia; Cancer Nurses Society of Australia, 165 Sovereign Hill Drive, Gabbadah, Western Australia, 6041, Australia; Centre for Children's Health Research, Children's Health Queensland Hospital and Health Services, South Brisbane, 4101, Australia.

Purpose: Chemotherapy-induced diarrhoea (CID) and constipation (CIC) are among the most common and severe gastrointestinal symptoms related to chemotherapy. This review aimed to identify and describe the evidence for non-pharmacological interventions for the management of CID and CIC.

Methods: The scoping review was based on the Joanna Briggs Institute methodology and reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist.

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A systematic review of the cost-effectiveness of maternity models of care.

BMC Pregnancy Childbirth

December 2023

School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, Qld, Australia.

Objectives: In this systematic review, we aimed to identify the full extent of cost-effectiveness evidence available for evaluating alternative Maternity Models of Care (MMC) and to summarize findings narratively.

Methods: Articles that included a decision tree or state-based (Markov) model to explore the cost-effectiveness of an MMC, and at least one comparator MMC, were identified from a systematic literature review. The MEDLINE, Embase, Web of Science, CINAHL and Google Scholar databases were searched for papers published in English, Arabic, and French.

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Clinical decision support systems for chronic obstructive pulmonary disease (COPD) in hospitals: A systematic review.

Digit Health

December 2023

Biomedical Informatics and Digital Health, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.

Objectives: To synthesise the literature on clinical decision support (CDS) systems for chronic obstructive pulmonary disease (COPD). We aimed to (1) describe existing COPD CDS systems that have been designed, developed or are being used in practice, (2) describe the impact of COPD CDS systems on outcomes and (3) identify barriers and facilitators to implementation of COPD CDS systems.

Methods: Five databases were searched to identify relevant studies.

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Article Synopsis
  • Enhancing healthcare access for ethnic minorities is crucial, yet there's limited understanding of how to effectively incorporate race and ethnicity data into large-scale global studies, particularly regarding COVID-19.
  • The COVID-19 Critical Care Consortium study analyzed data from 7,394 adults across 32 countries, focusing on race and ethnicity in relation to treatment and in-hospital mortality among patients admitted to intensive care from January 2020 to February 2022.
  • Results revealed significant disparities, with Indigenous ethnic groups in the US and Australia facing higher disease severity and mortality rates, highlighting the persistent healthcare inequalities affecting these populations.
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Article Synopsis
  • - This review focuses on three main objectives: understanding factors affecting oxygen levels in patients on ECMO, examining how hyperoxia impacts patient outcomes, and offering practical guidance on adjusting oxygen levels during treatment.
  • - Research included observational and interventional studies as well as guidelines from the Extracorporeal Life Support Organization to gather evidence about hyperoxia and clinical results.
  • - Findings indicate that both the ECMO machine and a patient’s natural heart and lung function influence systemic oxygenation, with high risks of hyperoxia emerging during treatment, which can increase the chances of in-hospital mortality.
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From pilot to a multi-site trial: refining the Early Detection of Deterioration in Elderly Residents (EDDIE +) intervention.

BMC Geriatr

December 2023

Australian Centre for Health Services Innovation and Centre for Healthcare Transformation, School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, Australia.

Background: Early Detection of Deterioration in Elderly Residents (EDDIE +) is a multi-modal intervention focused on empowering nursing and personal care workers to identify and proactively manage deterioration of residents living in residential aged care (RAC) homes. Building on successful pilot trials conducted between 2014 and 2017, the intervention was refined for implementation in a stepped-wedge cluster randomised trial in 12 RAC homes from March 2021 to May 2022. We report the process used to transition from a small-scale pilot intervention to a multi-site intervention, detailing the intervention to enable future replication.

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Stakeholders' preferences for the design and delivery of virtual care services: A systematic review of discrete choice experiments.

Soc Sci Med

January 2024

Australian Centre for Health Services Innovation, Centre for Healthcare Transformation, School of Social Work and Public Health, Queensland University of Technology, 60 Musk Avenue, Kelvin Grove, QLD, 4059, Australia. Electronic address:

This systematic review aimed to synthesise evidence from discrete choice experiments (DCEs) eliciting preferences for virtual models of care, as well as to assess the quality of those DCEs and compare the relative preferences for different stakeholder groups. Articles were included if published between January 2010 and December 2022. Data were synthesised narratively, and attributes were assessed for frequency, significance, and relative importance using a semi-quantitative approach.

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Most interventions in paediatric critical care lack high grade evidence. We aimed to identify the key research priorities and key clinical outcome measures pertinent to research in paediatric intensive care patients. Modified three-stage Delphi study combining staged online surveys, followed by a face-to-face discussion and final voting.

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Post-traumatic stress and health-related quality of life after admission to paediatric intensive care: Longitudinal associations in mother-child dyads.

Aust Crit Care

January 2024

School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, Australia; School of Psychology, The University of Queensland, Brisbane, Australia.

Article Synopsis
  • The study investigates the relationship between post-traumatic stress symptoms (PTSS) and health-related quality of life (HRQoL) in children and their mothers after pediatric intensive care unit (PICU) admissions.
  • Using data from 282 mother-child pairs, researchers found that higher maternal PTSS was linked to worsening child PTSS and lower maternal mental HRQoL, indicating a unidirectional influence from mothers to children.
  • The findings suggest that mothers' PTSS significantly impacts their children's psychological outcomes following critical pediatric illnesses, highlighting the need for supportive interventions for both mothers and children.
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Background: Despite a focus of opioid-related research internationally, there is limited understanding of long-term opioid use in adults following injury. We analysed data from the 'Community Opioid Dispensing after Injury' data linkage study.

Aims: This paper aims to describe the baseline characteristics of the injured cohort and report opioid dispensing patterns following injury-related hospitalisations.

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Objectives: To develop a consensus on evidence-based principles and recommendations for perioperative hypothermia prevention in the Australian context.

Design: This study was informed by CAN-IMPLEMENT using the ADAPTE process: (1) formation of a multidisciplinary development team; (2) systematic search process identifying existing guidance for perioperative hypothermia prevention; (3) appraisal using the AGREE II Rigor of Development domain; (4) extraction of recommendations from guidelines meeting a quality threshold using the AGREE-REX tool; (5) review of draft principles and recommendations by multidisciplinary clinicians nationally and (6) subsequent round of discussion, drafting, reflection and revision by the original panel member team.

Setting: Australian perioperative departments.

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Does Legislation Impede Data Sharing in Australia Across Institutions and Jurisdictions? A Scoping Review.

J Med Syst

November 2023

Associate Professor of Ethics and Professionalism, Medical School, Academy for Medical Education, University of Queensland, Brisbane, Australia.

In Australia, regulations governing data, including formal legislation and policies promulgated by private and public agencies, are often seen as a barrier to data sharing. This sharing can include between institutions, as well as across jurisdictional borders in a federated jurisdiction such as Australia. In some cases, these regulations place a barrier to sharing data across borders or between institutions without a prerequisite requirement.

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Background: Treatment decisions for men diagnosed with prostate cancer depend on a range of clinical and patient characteristics such as disease stage, age, general health, risk of side effects and access. Associations between treatment patterns and area-level factors such as remoteness and socioeconomic disadvantage have been observed in many countries.

Objective: To model spatial differences in interventional treatment rates for prostate cancer at high spatial resolution to inform policy and decision-making.

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Quality of life and family functioning soon after paediatric brain tumour diagnosis: A cross-sectional observational study.

Eur J Oncol Nurs

December 2023

Cancer and Palliative Care Outcomes Centre, Centre for Healthcare Transformation, School of Nursing, Faculty of Health, Queensland University of Technology, 515 Ring Rd, Kelvin Grove, QLD, 4059, Australia; Children's Brain Cancer Centre at the Centre for Children's Health Research, Children's Health Queensland Hospital and Health Service, Queensland Government, 62 Graham St, South Brisbane, QLD, 4101, Australia.

Purpose: There is scant scholarly exploration of quality of life in families with a child who has a brain tumour early after diagnosis, despite this being a pivotal point in their illness trajectory. We aimed to describe quality of life in children and their parents, and family functioning, within six months of diagnosis; and to examine if this differed for various subpopulations.

Method: This is a cross-sectional analysis of baseline data of an ongoing longitudinal survey.

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Introduction: Physical inactivity is a risk factor for repeat cardiac events and all-cause mortality in coronary heart disease (CHD). Cardiac rehabilitation, a secondary prevention programme, aims to increase physical activity levels in this population from a reported low baseline. This trial will investigate the effectiveness and implementation of a very brief physical activity intervention, comparing different frequencies of physical activity measurement by cardiac rehabilitation clinicians.

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How digital health translational research is prioritised: a qualitative stakeholder-driven approach to decision support evaluation.

BMJ Open

November 2023

Biomedical Informatics and Digital Health, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales, Australia.

Objectives: Digital health is now routinely being applied in clinical care, and with a variety of clinician-facing systems available, healthcare organisations are increasingly required to make decisions about technology implementation and evaluation. However, few studies have examined how digital health research is prioritised, particularly research focused on clinician-facing decision support systems. This study aimed to identify criteria for prioritising digital health research, examine how these differ from criteria for prioritising traditional health research and determine priority decision support use cases for a collaborative implementation research programme.

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Anticipatory anxiety and participation in cancer screening. A systematic review.

Psychooncology

December 2023

Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.

Objectives: To synthesize current evidence on the association between anticipatory anxiety, defined as apprehension-specific negative affect that may be experienced when exposed to potential threat or uncertainty, and cancer screening to better inform strategies to maximize participation rates.

Methods: Searches related to cancer screening and anxiety were conducted in seven electronic databases (APA PsycINFO, Scopus, Web of Science, Embase, Cochrane Library, PubMed, CINAHL), with potentially eligible papers screened in Covidence. Data extraction was conducted independently by multiple authors.

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