544 results match your criteria: "Centre for Evidence-based Health Care[Affiliation]"

Aims: Digital counselling has gained paramount importance for coronary artery disease (CAD) patients' treatment in recent years. It has been shown to provide a multitude of benefits, including improved risk factors and enhanced lifestyles. No previous reviews have emphasized the interactiveness of digital counselling.

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Behavioural and social drivers of human papillomavirus vaccination in eThekwini District of KwaZulu-Natal Province, South Africa.

PLoS One

December 2024

Faculty of Health Sciences, Department of Medicine & CIDRI-Africa, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.

Background: Cervical cancer is the second most common cancer in women in South Africa. Infection with high-risk types of human papillomavirus (HPV) is the cause of cervical cancer, which can be prevented by HPV vaccination. However, there is wide variation in HPV vaccination coverage among the urban districts of South Africa; with the lowest coverage being 40% in eThekwini, KwaZulu-Natal.

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Aim: To critically appraise and synthesise qualitative evidence about patients' experiences of healthcare professionals' competence in digital counselling in healthcare settings.

Design: A qualitative systematic review.

Methods: The review followed the Joanna Briggs Institute methodology for systematic reviews of qualitative evidence.

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Home visits for preterm/low birthweight infants in South Africa: Qualitative evidence synthesis.

Afr J Prim Health Care Fam Med

November 2024

Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.

Background: Prematurity and low birth weight (LBW) are the main causes of neonatal mortality in South Africa (SA). Home visits by lay health workers (LHWs) may be effective in addressing this.

Aim: To inform a national guideline on LHW home visits as part of the Global Evidence, Local Adaptation (GELA) project, we conducted a rapid qualitative evidence synthesis exploring the acceptability, feasibility and equitability of this intervention for preterm and LBW babies.

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Article Synopsis
  • Academic-government partnerships are crucial for providing timely evidence to inform decision-making during emergencies, like the COVID-19 pandemic in South Africa, utilizing integrated knowledge translation (KT) approaches.
  • The study employed Cochrane's KT Framework to analyze activities, such as producing rapid reviews and engaging stakeholders, that facilitated evidence-informed decision-making.
  • Key findings emphasize the significance of authentic partnerships, systematic stakeholder engagement, tailored KT strategies, and the need for ongoing evaluation to improve future emergency response efforts.
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Aim: To identify and integrate the best evidence on nurses' perceptions of organisational attractiveness and related factors in health care.

Design: A mixed methods systematic review.

Methods: The review followed the Joanna Briggs Institute Mixed Methods Systematic Review methodology and a convergent segregated approach which involved separate qualitative and quantitative syntheses followed by integration in a narrative form.

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Rationale: Postpartum haemorrhage (PPH) is common and potentially life-threatening. The antifibrinolytic drug tranexamic acid (TXA) is recommended for treating PPH; it reduces the risk of death from haemorrhage by one-third when given soon after bleeding onset, but not overall risk of death. Interest in whether TXA may be effective in preventing PPH is growing.

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Background And Objectives: Despite the robustness of evidence-based practice in increasing efficiency in nursing care and improving patient safety, using evidence in practice is still rare in mental health nursing. This correlational descriptive research aimed to explore the factors and examine the relationship between attitudes, knowledge/skills, organizational culture, mentorship, and demographic factors to evidence-based practices among mental health nurses working in psychiatric hospitals in Thailand.

Methods: The sample consisted of 255 nurses working in psychiatric hospitals under the Thai Department of Mental Health, located in service units across the country's four regions.

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Introduction: Ambulatory care settings are at high risk for errors when identifying patients and matching them to their intended care.

Objective: The objective of this project was to improve correct and consistent patient identification and matching to their intended care by nurses in ambulatory care settings.

Methods: The seven-phase JBI Evidence Implementation Framework was used to guide this project.

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Building sustainable capacity to adopt, adapt or develop child health guidelines, Malawi, Nigeria and South Africa.

Bull World Health Organ

October 2024

Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa.

Article Synopsis
  • Many child health guidelines in Malawi, Nigeria, and South Africa are old and don’t involve enough people in making decisions.
  • The GELA project helped create better guidelines by getting groups together to discuss and prioritize the most important child health topics, using current evidence to adapt existing recommendations.
  • National teams in these countries created five new recommendations for child health, but they needed more evidence and training to make good decisions.
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Aim: To map the characteristics of nursing educators' competency standards for practice from the existing literature, examine the evidence and identify commonalities and differences.

Background: Many countries or regions have produced nursing educator standards, however, there is no common set of standards or competencies used globally. Mapping these nursing educator standards should identify a common set of standards that can be applied across any nursing educator practice setting.

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Lag screw versus locking plate fixation for traumatic displaced medial malleolar fractures: a systematic review and meta-analysis.

Orthop Traumatol Surg Res

September 2024

Centre for Evidence-Based Health Care, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Cochrane Taiwan, Taipei Medical University, Taipei, Taiwan; Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Division of General Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Background: Lag screw fixation (LSF) or locking plate fixation (LPF) are both recommended for the treatment of medial malleolar fractures (MMFs). However, no standard has been established for attaining optimal surgical treatment or functional recovery. We hypothesized that LPF for MMFs would result in superior outcomes compared to LSF.

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Background: Some dietary recommendations continue to recommend carbohydrate restriction as a cornerstone of dietary advice for people with diabetes.

Purpose: We compared the cardiometabolic effects of diets higher in both fiber and carbohydrate with lower carbohydrate lower fiber diets in type 1 or type 2 diabetes.

Data Sources: MEDLINE, Embase, and the Cochrane Database of Systematic Reviews up to June 24, 2024, with additional hand searching.

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Article Synopsis
  • The study conducted a systematic review of research on malaria rapid diagnostic tests (mRDTs) and their impact on patient outcomes in sub-Saharan Africa.
  • A total of 4717 studies were initially identified, leading to the inclusion of 24 primary quantitative studies that primarily measured the therapeutic effects of mRDTs.
  • Findings indicated that while most studies were of good methodological quality, there were significant challenges in implementing mRDTs, particularly related to health system constraints and test acceptability among patients.
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Objective: The aim of this systematic review will be to explore the experiences of empathy in informal caregivers providing care for persons with dementia.

Introduction: Positive caregiving experiences of informal caregivers providing care for persons with dementia have many beneficial outcomes, such as improved well-being of both caregivers and care receivers and a higher quality of care for the persons with dementia. Empathy is a factor associated with positive caregiving experiences and is strongly correlated with reduced depression and reduced anxiety in informal caregivers of persons with dementia.

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Article Synopsis
  • The CEBHA+ program offered a course on evidence-based public health in five sub-Saharan African countries to build skills and capacity among individuals and institutions.
  • The study used the RE-AIM and PRISM frameworks to assess and learn from the course's implementation, involving reflections and discussions among country teams.
  • Results showed that 130 participants improved their EBPH knowledge, faced challenges with hybrid learning formats, and noted the importance of contextualizing content for local public health needs, emphasizing that ongoing funding is crucial for institutionalizing these initiatives.
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Defining and identifying the critical elements of operational readiness for public health emergency events: a rapid scoping review.

BMJ Glob Health

August 2024

Country Readiness and Strengthening Department, World Health Emergencies Programme, World Health Organization, Geneva, Switzerland.

Introduction: COVID-19 showed that countries must strengthen their operational readiness (OPR) capabilities to respond to an imminent pandemic threat rapidly and proactively. We conducted a rapid scoping evidence review to understand the definition and critical elements of OPR against five core sub-systems of a new framework to strengthen the global architecture for Health Emergency Preparedness Response and Resilience (HEPR).

Methods: We searched MEDLINE, Embase, and Web of Science, targeted repositories, websites, and grey literature databases for publications between 1 January 2010 and 29 September 2021 in English, German, French or Afrikaans.

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GRADE guidance 39: using GRADE-ADOLOPMENT to adopt, adapt or create contextualized recommendations from source guidelines and evidence syntheses.

J Clin Epidemiol

October 2024

Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, L8S 4L8, Ontario, Canada; Clinical Epidemiology and Research Center (CERC), Humanitas University & Humanitas Research Hospital, Via Rita Levi Montalcini 4 - 20090 Pieve Emanuele, Milano, Italy; Nottingham Ningbo GRADE Centre, School of Economics, The University of Nottingham Ningbo China, Ningbo, China; China European Research Executive Agency, European Commission, Brussels, Belgium. Electronic address:

Background And Objective: The Grading of Recommendations, Assessment, Development and Evaluations (GRADE)-ADOLOPMENT methodology has been widely used to adopt, adapt, or de novo develop recommendations from existing or new guideline and evidence synthesis efforts. The objective of this guidance is to refine the operationalization for applying GRADE-ADOLOPMENT.

Methods: Through iterative discussions, online meetings, and email communications, the GRADE-ADOLOPMENT project group drafted the updated guidance.

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Article Synopsis
  • The study focuses on identifying COVID-19 patients at risk of deterioration to inform treatment intensity decisions, utilizing routine blood tests for assessment.
  • Researchers aimed to evaluate how effectively these laboratory tests can predict patient mortality and the progression of COVID-19 severity.
  • A thorough search of multiple medical databases was conducted to include various study designs, and data was analyzed for prognostic accuracy of the tests in question.
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Shared decision-making in healthcare: development and assessment of the translated Finnish version of the SDM-Q-9.

Scand J Public Health

August 2024

Faculty of Social Sciences and Business Studies, Department of Health and Social Management, University of Eastern Finland, Kuopio, Finland.

Aims: The aim of this study was to assess the cultural validity and reliability of a Finnish version of the nine-item Shared Decision-Making Questionnaire (SDM-Q-9) in a sample of patients with different sociodemographic characteristics.

Method: The original SDM-Q-9 was translated into Finnish with the agreement of the developers of the original scale. The standardised translation procedure was followed by a pilot test of the questionnaire.

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Objective: The objective of this review was to examine the role of adverse drug events (ADEs) caused by pharmacological interventions in cost-effectiveness models for diabetes mellitus, diabetic retinopathy, and diabetic macular edema.

Introduction: Guidelines for economic evaluation recognize the importance of including ADEs in the analysis, but in practice, consideration of ADEs in cost-effectiveness models seem to be vague. Inadequate inclusion of these harmful outcomes affects the reliability of the results, and the information provided by economic evaluation could be misleading.

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As healthcare depends on health information technology, there is a growing need for Health Informatics competencies in daily practice. This review aimed to explore how the teaching of education in HI has been arranged. 28 publications, published in English between 2016 and 2020 and obtained from selected bibliographic databases, were reviewed.

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Aim: The aim of the study was to review the 2010 Australian nurse teacher professional practice standards ('the Standards') to see if they were still relevant to current nursing educator practice in any practice setting, such as academia or clinical settings.

Background: It has been over 10 years since 'the Standards have been reviewed. Nurse education practice has met many challenges in the past decade, so it is timely to evaluate whether the Standards are still relevant to nursing educators today.

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Drug-Resistant Tuberculosis Case-Finding Strategies: Scoping Review.

JMIR Public Health Surveill

June 2024

Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Background: Finding individuals with drug-resistant tuberculosis (DR-TB) is important to control the pandemic and improve patient clinical outcomes. To our knowledge, systematic reviews assessing the effectiveness, cost-effectiveness, acceptability, and feasibility of different DR-TB case-finding strategies to inform research, policy, and practice, have not been conducted and the scope of primary research is unknown.

Objective: We therefore assessed the available literature on DR-TB case-finding strategies.

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Objectives: The objectives of this study are to assess reporting of evidence-based healthcare (EBHC) e-learning interventions using the Guideline for Reporting Evidence-based practice Educational interventions and Teaching (GREET) checklist and explore factors associated with compliant reporting.

Design: Methodological cross-sectional study.

Methods: Based on the criteria used in an earlier systematic review, we included studies comparing EBHC e-learning and any other form of EBHC training or no EBHC training.

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