25 results match your criteria: "Centre for Evidence-Based Orthopedics.[Affiliation]"
Lancet
December 2024
Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital Rigshospitalet, Tagensvej 22, DK-2200 Copenhagen, Denmark; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.
Osteoarthritis Cartilage
February 2025
Clinical Epidemiology Unit, Orthopedics, Faculty of Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:
Objective: To assess the 5-year effects of arthroscopic partial meniscectomy (APM) vs. placebo surgery on the development of the structural changes of the knee by magnetic resonance imaging (MRI).
Design: This multicentre, randomized, participant- and outcome-assessor-blinded, placebo-surgery-controlled trial was carried out in Finland.
Lancet
June 2024
Department of Orthopaedics and Traumatology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland; Finnish Centre for Evidence-Based Orthopedics, University of Helsinki, Helsinki, Finland.
Background: Chronic subdural haematoma is a common surgically treated intracranial emergency. Burr-hole drainage surgery, to evacuate chronic subdural haematoma, involves three elements: creation of a burr hole for access, irrigation of the subdural space, and insertion of a subdural drain. Although the subdural drain has been established as beneficial, the therapeutic effect of subdural irrigation has not been addressed.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2024
Centre for Evidence-Based Orthopedics, Department of Orthopedic Surgery, Zealand University Hospital, Køge, Denmark.
Background: Network meta-analyses can be valuable for decision-makers in guiding clinical practice. However, for network meta-analysis results to be reliable, the assumptions of both transitivity and coherence must be met, and the methodology should adhere to current best practices. We aimed to assess whether network meta-analyses of randomized controlled trials (RCTs) comparing interventions for proximal humerus fractures provide reliable estimates of intervention effects.
View Article and Find Full Text PDFActa Orthop
November 2023
Department of Medical Imaging, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, the Netherlands.
Background And Purpose: Concerns exist regarding the generalizability of results from randomized controlled trials (RCTs) evaluating arthroscopic partial meniscectomy (APM) to treat degenerative meniscus tears. It has been suggested that study populations are not representative of subjects selected for surgery in daily clinical practice. Therefore, we aimed to compare patients included in trials and prospective cohort studies that received APM for a degenerative meniscus tear.
View Article and Find Full Text PDFActa Orthop
October 2023
Department of Orthopedic Surgery and Traumatology, Lillebaelt Hospital, University Hospital of Southern Denmark; Department of Orthopedic Surgery and Traumatology, Odense University Hospital and Department of Clinical Research, University of Southern Denmark, Denmark.
Background And Purpose: Humeral shaft fractures (HSF) can be treated surgically or non-surgically. National trends and distributions are sparsely reported. We present the temporal trends in epidemiology of adult HSF in Denmark, with the primary aim of reporting HSF incidences, and the secondary aim of reporting on the primary treatment management.
View Article and Find Full Text PDFJ Med Internet Res
July 2023
The Research Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospital, Slagelse, Denmark.
Background: Digital health interventions for managing chronic conditions have great potential. However, the benefits and harms are still unclear.
Objective: This systematic review and meta-analysis aimed to investigate the benefits and harms of digital health interventions in promoting physical activity in people with chronic conditions.
J Clin Epidemiol
April 2023
Centre for Evidence-Based Orthopedics, Department of Orthopedic Surgery, Zealand University Hospital, Køge, Denmark.
Objectives: To assess how much protocols reduce methodological flexibility and variation of results in meta-analyses comparing operative with nonoperative treatments for proximal humerus fractures.
Study Design And Setting: A meta-epidemiological study. We searched four bibliographic databases for eligible meta-analyses.
Clin Orthop Relat Res
April 2022
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University and Monash Department of Clinical Epidemiology, Cabrini Institute, Melbourne, Australia.
Background: Tennis elbow is a common painful enthesopathy of the lateral elbow that limits upper limb function and frequently results in lost time at work. Surgeons often recommend surgery if symptoms persist despite nonsurgical management, but operations for tennis elbow are inconsistent in their efficacy, and what we know about those operations often derives from observational studies that assume the condition does not continue to improve over time. This assumption is largely untested, and it may not be true; meta-analyzing results from the control arms of tennis elbow studies can help us to evaluate this premise, but to our knowledge, this has not been done.
View Article and Find Full Text PDFJ Clin Epidemiol
February 2022
Centre for Evidence-Based Orthopedics, Department of Orthopedic Surgery, Zealand University Hospital, Køge, Denmark.
Objective: To investigate the association between methodological quality and reported conclusions of meta-analyses comparing operative with non-operative treatments for proximal humerus fractures.
Study Design And Setting: Cross-sectional meta-epidemiological study. We searched EMBASE, PubMed, The Cochrane Library, and Web of Science for systematic reviews with meta-analyses comparing non-operative with operative treatments for proximal humerus fractures.
Bone Joint J
May 2021
Division of Orthopedic Surgery, McMaster University, Hamilton, Canada.
Aims: This study reviews the past 30 years of research from the Canadian Orthopedic Trauma Society (COTS), to identify predictive factors that delay or accelerate the course of randomized controlled trials in orthopaedic trauma.
Methods: We conducted a methodological review of all papers published through the Canadian Orthopaedic Trauma Society or its affiliates. Data abstracted included: year of publication; journal of publication; study type; number of study sites; sample size; and achievement of sample size goals.
Br J Sports Med
November 2020
Finnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki, Helsinki, Finland
Objectives: To assess the long-term effects of arthroscopic partial meniscectomy (APM) on the development of radiographic knee osteoarthritis, and on knee symptoms and function, at 5 years follow-up.
Design: Multicentre, randomised, participant- and outcome assessor-blinded, placebo-surgery controlled trial.
Setting: Orthopaedic departments in five public hospitals in Finland.
Cureus
May 2020
Orthopaedic Surgery, McMaster University, Hamilton, CAN.
Objectives Nonunions of tibial shaft fractures have profound implications on patient quality of life and are associated with physical and mental suffering. Radiographic Union Score for Tibia Fractures (RUST) may serve as an important prognostic tool for identifying patients at a high risk of nonunion. Design We used data from the Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) and Fluid Lavage of Open Wounds (FLOW) trials to explore the association of three-month RUST scores with nonunion in patients with tibial shaft fractures treated with intramedullary nailing.
View Article and Find Full Text PDFBMJ Open
June 2020
Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Uusimaa, Finland.
Introduction: Chronic subdural haematomas (CSDHs) are one of the most common neurosurgical conditions. The goal of surgery is to alleviate symptoms and minimise the risk of symptomatic recurrences. In the past, reoperation rates as high as 20%-30% were described for CSDH recurrences.
View Article and Find Full Text PDFJ Occup Environ Med
May 2020
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada (Dr Rehman, Mr Jones, Dr Madden, Ms Heels-Ansdell, Dr Busse); Canadian Academy of Osteopathy, Hamilton, Ontario, Canada (Dr Rehman); The Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada (Dr Rehman, Dr Busse); Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, Ontario, Canada (Dr Madden); Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada (Dr Busse) and The Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University, Hamilton, Ontario, Canada (Dr Busse).
Objectives: We explored the association of compensation status with return to work (RTW) after tibial fracture.
Methods: Eligible patients were adults with tibial shaft fractures enrolled in the Trial to Re-evaluate Ultrasound in the Treatment of Tibial Fractures. We explored the association between disability benefits and/or litigation and RTW using multivariable discrete interval hazard analysis, adjusting for sex, age, country of residence, smoking status, body mass index, polytrauma, fracture severity, fracture gap, pain severity, and physical functioning.
BMJ Open
November 2019
Finnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Introduction: Although a great majority of patients with cervical radiculopathy syndrome can successfully be treated non-operatively, a considerable proportion experience persistent symptoms, severe enough to require neurosurgical intervention. During the past decade, cervical spine procedures have increasingly been performed on an outpatient basis and retrospective database analyses have shown this to be feasible and safe. However, there are no randomised controlled studies comparing outpatient care with inpatient care, particularly with emphasis on the patients' perception of symptom relief and their ability to return to normal daily activities and work.
View Article and Find Full Text PDFOsteoarthritis Cartilage
October 2019
Finnish Centre for Evidence-Based Orthopedics (FICEBO), Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
OTA Int
September 2019
Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics.
Objectives: To describe the regional distribution of fractures sustained by women and health care system characteristics across 17 low- and middle-income countries (LMICs).
Methods: The INternational ORthopaedic MUlticentre Study in fracture care (INORMUS) is an observational study collecting data on patients in LMICs who sustained a fracture or musculoskeletal injury. As a planned analysis for the INORMUS study, we explored differences in fracture locations and demographics reported among 9878 female patients who sustained a fracture within 17 LMICs in 5 regions (China, Africa, India, Other Asia, and Latin America).
Br J Sports Med
June 2020
Division of Physiotherapy, Linköping University, Linköping, Sweden.
Objective: To determine the benefits and harms of subacromial decompression surgery in adult patients with subacromial pain syndrome lasting for more than 3 months.
Design: Systematic review with meta-analysis.
Main Outcome Measures: Pain, physical function and health-related quality of life.
BMJ
July 2018
Department of Orthopedics and Traumatology, Helsinki University Hospital, Töölö hospital, Helsinki, Finland.
Objective: To assess the efficacy of arthroscopic subacromial decompression (ASD) by comparing it with diagnostic arthroscopy, a placebo surgical intervention, and with a non-operative alternative, exercise therapy, in a more pragmatic setting.
Design: Multicentre, three group, randomised, double blind, sham controlled trial.
Setting: Orthopaedic departments at three public hospitals in Finland.
BMJ Open
September 2016
Department of Orthopaedic Surgery, Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, The Netherlands.
Objective: The objective of this systematic review of the literature was to identify the predictors of functional outcome after total hip arthroplasty (THA).
Method: A systematic literature search in Web of Science, CINAHL, EMBASE and PubMed was conducted on 23 June 2015. The articles were selected based on their quality, relevance and measurement of the predictive factor.
Orthop Rev (Pavia)
June 2016
Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, ON, Canada.
Knee osteoarthritis is a leading cause of disability around the world. Knee bracing provides a conservative management option for symptom relief. A variety of different bracing types, manufacturers and products are currently available on the market.
View Article and Find Full Text PDFOrthop Rev (Pavia)
December 2015
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, Department of Surgery, McMaster University, Hamilton, ON, Canada.
The number of outpatient orthopedic surgeries performed within North America continues to increase. The impact of this change in services on patient outcomes is largely unknown. The objective of this review is to compare patient outcomes and associated costs for outpatient orthopedic surgeries traditionally performed in hospital to inpatient surgeries, as well as to summarize the eligibility and preoperative education requirements for outpatient orthopedic surgery in North America.
View Article and Find Full Text PDFClin Med Insights Arthritis Musculoskelet Disord
August 2015
Global Research Solutions, Inc., Burlington, Ontario, Canada. ; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
The treatment gap between conservative management and total knee arthroplasty may leave patients with moderate cases of knee osteoarthritis (OA) without an ideal treatment option. The KineSpring(®) Knee Implant System may be a viable treatment option to fill the treatment gap for patients with knee OA who are not willing or inappropriate candidates for total knee arthroplasty, yet do not demonstrate relief with conservative treatments. This current paper reports a series of patients who received the KineSpring System and were followed for five years.
View Article and Find Full Text PDFClin Med Insights Arthritis Musculoskelet Disord
March 2015
Global Research Solutions, Inc., Burlington, Ontario, Canada. ; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, Ontario, Canada.
Carbon-fiber-reinforced polyetheretherketone (CFR-PEEK) has been successfully used in orthopedic implants. The aim of this systematic review is to investigate the properties, technical data, and safety of CFR-PEEK biomaterial and to evaluate its potential for new innovation in the design of articulating medical devices. A comprehensive search in PubMed and EMBASE was conducted to identify articles relevant to the outcomes of CFR-PEEK orthopedic implants.
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